194 completed, 70 unknown, 52 terminated, 48 recruiting. 202 Phase 2, 84 Phase 1, 43 Phase 3, 27 Not applicable, 4 Early Phase 1.
Follow Adenocarcinoma of Lung: new trials by email Literature Review of Adenocarcinoma of Lung trials Research Report on Adenocarcinoma of Lung
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Firmonertinib Plus Chemotherapy for Unresectable EGFR PACC-Mutant Stage III Lung Cancer: A Phase II Study Firmonertinib, Platinum-based chemotherapy - Lung Adenocarcinoma, Stage III Lung Cancer | Phase 2 | Not yet recruiting | Hunan Province Tumor Hospital | 27 | 2026-11-01 | 2026-10-16 |
| Phase 1 Study of NW-301V TCR-T Cells in Advanced Solid Tumors With KRAS G12V Mutation Fludarabine, Cyclophosphamide, NW-301V - Advanced Solid Cancer, Pancreatic Ductal Adenocarcinoma (PDAC) | Phase 1 | Not yet recruiting | Neowise Biotechnology | 66 | 2026-10-01 | 2026-10-15 |
| SL-28 for Advanced Solid Tumours SL-28 - Head & Neck Cancer, Pancreas Carcinoma | Phase 1 / Phase 2 | Recruiting | Second Life Therapeutics | 60 | 2026-08-14 | 2026-09-15 |
| Inhaled Cromolyn Sodium in Patients With Locally Advanced Lung Cancer Cromolyn Sodium - Locally Advanced Non-Small Cell Lung Cancer, Lung Adenocarcinoma | Phase 1 | Not yet recruiting | Carcinex Inc | 10 | 2026-08-01 | 2026-07-01 |
| DBC-664 in Adult Patients With Solid Tumors DBC-664 - Malignant Germ Cell Tumor, Lung Adenocarcinoma | Phase 1 | Recruiting | Duboce Biopharmaceuticals, Inc. | 210 | 2026-07-17 | 2026-09-29 |
| Furmonertinib Plus Radiotherapy for EGFR+ NSCLC With Pleural Effusion Furmonertinib, Thoracic Radiotherapy (TRT) - Lung Cancer (NSCLC), Malignant Pleural Effusions (Mpe)- Pleurodesis | Phase 2 | Not yet recruiting | Jiangmen Central Hospital | 63 | 2026-07-01 | 2026-07-17 |
| Aumolertinib Combined With Phased Chemotherapy for EGFR L858R Lung Adenocarcinoma Aumolertinib combined with phased chemotherapy (pemetrexed and carboplatin) - Lung Adenocarcinoma Metastatic | Phase 2 | Recruiting | Taipei Medical University Hospital | 50 | 2026-06-09 | 2026-06-18 |
| CLINICAL STUDY TO IDENTIFY BIOMARKERS FOR TUMOR SPREAD THROUGH AIR SPACES STATUS Lung Adenocarcinoma | Not yet recruiting | Universidade Nova de Lisboa | 140 | 2026-06-01 | 2026-06-05 | |
| Deep Learning Time-Series Prediction of Long-Term Growth Patterns of Pulmonary Ground-Glass Nodules Using Serial CT Serial Thin-Slice Chest CT - Pulmonary Nodules, Lung Neoplasms | Not yet recruiting | Peking University People's Hospital | 4750 | 2026-06-01 | 2026-06-15 | |
| Peripheral Blood ETASTs for Predicting Efficacy of Chemoimmunotherapy in NSCLC Circulating Tumor-Specific T Cell Nanodetection Technology (CTT-NanoDT) - Non-Small Cell Lung Cancer, Lung Adenocarcinoma | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 80 | 2026-04-01 | 2026-02-06 | |
| Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases FSRT, HA-WBRT-SIB, Bevacizumab - Lung Adenocarcinoma, Brain Metastases | Phase 3 | Recruiting | Sun Yat-sen University | 220 | 2026-03-20 | 2026-04-06 |
| Vortioxetine for Cognitive Function in ALK-positive NSCLC Treated With Lorlatinib Advanced ALK/ROS1-positive NSCLC, Carcinoma, Non-Small-Cell Lung (NSCLC) | Recruiting | Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo | 24 | 2026-03-10 | 2026-06-08 | |
| Engagement of Veterans With Lung Cancer Lay Health Worker (LHW) Planning, Usual Care Group - Lung Cancer (NSCLC), Lung Adenocarcinoma | Not applicable | Recruiting | Palo Alto Veterans Institute for Research | 194 | 2026-02-27 | 2026-03-03 |
| Partial Tumor Irradiation and Immunotherapy for Unresectable Lung Cancer Partial Tumor Irradiation - Lung Adenocarcinoma, Bulky Tumors | Not applicable | Recruiting | Karl Landsteiner University of Health Sciences | 10 | 2026-02-02 | 2026-02-20 |
| PHOENIX: QL1706 Plus Chemotherapy and Bevacizumab in AGA-Resistant, PD-L1 ≥50% Non-Squamous NSCLC QL1706 (bispecific antibody targeting PD-1 and CLTA-4) - Lung Adenocarcinoma | Phase 2 | Not yet recruiting | Guangdong Association of Clinical Trials | 61 | 2026-01-31 | 2026-02-17 |
| ADH1B and ALDH Gene Variants and Lung Cancer Risk Condition/Disease, Lung Cancer (Diagnosis) | Not yet recruiting | Kaohsiung Medical University | 100000 | 2026-01-01 | 2025-12-09 | |
| Evaluation of Different Sizes of Left-Sided Double-Lumen Tubes for Thoracic Surgery in a Tertiary Level Teaching Hospital Intubation of patients undergoing thoracic surgery with left sided double lumen tube - Lung Adenocarcinoma, Lung Abscess | Not applicable | Not yet recruiting | Tribhuvan University, Nepal | 60 | 2026-01-01 | 2026-01-28 |
| Prediction of Targeted Therapy Efficacy in EGFR-mutant Lung Cancer Patients Using AI-based Multimodal Data Comprehensive analysis through laboratory tests, imaging techniques, and clinical data - Lung Cancer (NSCLC), EGFR Activating Mutation | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 1000 | 2025-12-25 | 2025-12-17 | |
| Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma Biospecimen Collection, Computed Tomography Assisted Biopsy, Dapagliflozin Propanediol - Lung Adenocarcinoma, Stage IA1 Lung Cancer American Joint Committee on Cancer (AJCC) v8 | Early Phase 1 | Recruiting | Jonsson Comprehensive Cancer Center | 48 | 2025-12-02 | 2026-02-19 |
| Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors Biopsy, Biospecimen Collection, Computed Tomography - Metastatic Malignant Solid Neoplasm, Metastatic Melanoma | Phase 1 | Recruiting | Anusha Kalbasi | 18 | 2025-10-07 | 2026-03-17 |
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Carcinoma, Non-Small-Cell Lung (248) · Lung Neoplasms (229) · Adenocarcinoma, Bronchiolo-Alveolar (103) · Neoplasm Metastasis (17) · Neoplasms (16) · Pancreatic Neoplasms (16) · Ovarian Neoplasms (14) · Colorectal Neoplasms (12) · Small Cell Lung Carcinoma (12) · Adenocarcinoma (11) · Breast Neoplasms (10) · Melanoma (9) · Endometrial Neoplasms (8) · Triple Negative Breast Neoplasms (8)
Neoplasms by Site (422) · Neoplasms, Glandular and Epithelial (422) · Respiratory Tract Neoplasms (422) · Thoracic Neoplasms (422) · Neoplasms by Histologic Type (421) · Carcinoma (418) · Adenocarcinoma (411) · Neoplasms (406) · Respiratory Tract Diseases (292) · Lung Diseases (284) · Bronchial Neoplasms (248) · Carcinoma, Bronchogenic (248) · Lung Neoplasms (193) · Pathological Conditions, Signs and Symptoms (33) · Endocrine Gland Neoplasms (29)
Carboplatin (73) · Paclitaxel (51) · Radiotherapy (44) · Pemetrexed (43) · Cisplatin (42) · Bevacizumab (39) · Docetaxel (27) · Gemcitabine (27) · Erlotinib Hydrochloride (26) · Gefitinib (20) · pembrolizumab (15) · Taxes (13) · Cetuximab (11) · Vinorelbine (10) · Magnetic Resonance Spectroscopy (9)
Alliance for Clinical Trials in Oncology (28) · National Cancer Institute (NCI) (28) · SWOG Cancer Research Network (17) · Novartis Pharmaceuticals (15) · Fudan University (12) · Shanghai Pulmonary Hospital, Shanghai, China (10) · Radiation Therapy Oncology Group (9) · Memorial Sloan Kettering Cancer Center (8) · Wake Forest University Health Sciences (8) · Roswell Park Cancer Institute (7) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (6) · ECOG-ACRIN Cancer Research Group (5) · Eastern Cooperative Oncology Group (5) · Mayo Clinic (5) · Swiss Cancer Institute (5)
United States (218) · China (78) · South Korea (25) · France (24) · Canada (21) · Italy (20) · Spain (19) · Australia (18) · Taiwan (17) · Belgium (14) · Japan (14) · United Kingdom (14) · Israel (13) · Germany (11) · Singapore (10)
Antonius A. Miller, MD (4) · Arthur William Blackstock, MD (4) · Haiquan Chen, M.D. (4) · Martin J. Edelman, MD (4) · Daniel C. Betticher, MD (3) · Derick H. Lau, MD (3) · Howard L. West, MD (3) · Robert D. Timmerman, MD (3) · Afshin Dowlati, MD (2) · Antoinette J. Wozniak, MD (2) · Arkadiusz Dudek, MD (2) · Azam Ghafoor, M.D. (2)
PMID 27130468, PMID 11241082, PMID 12377323, PMID 12721251, PMID 14688710, PMID 14731343, PMID 14736927, PMID 14998842, PMID 15251940, PMID 15254048, PMID 15254054, PMID 15297403, PMID 15301880, PMID 15625373, PMID 15667949, PMID 15821648, PMID 15837967, PMID 15893009, PMID 16019107, PMID 16055865, PMID 16361616, PMID 16488712, PMID 16622435, PMID 16757720, PMID 16785054, PMID 16856022, PMID 16957145, PMID 17167137, PMID 17235046, PMID 17264337, PMID 17374834, PMID 17404369, PMID 17406356, PMID 17409914, PMID 17509725, PMID 17602078, PMID 17869017, PMID 18096059, PMID 18096565, PMID 18201795, PMID 18281656, PMID 18355490, PMID 18487565, PMID 18612151, PMID 18757331, PMID 18779603, PMID 18827613, PMID 19013107, PMID 19231158, PMID 19251095
U10CA032102 (19), U10CA031946 (15), U10CA180888 (7), 2016 (5), U10CA021115 (5), N01CM62201 (3), N01CM62209 (3), P30CA043703 (3), U10CA180821 (3), P30CA006973 (2), P30CA022453 (2), P30CA068485 (2), P50CA090949 (2), 2014 (1), 2023 (1)