17 completed, 5 terminated, 3 unknown, 2 withdrawn. 11 Phase 2, 9 Phase 1, 5 Phase 3, 3 Not applicable, 1 Early Phase 1.
Follow Dihematoporphyrin Ether: new trials by email Literature Review of Dihematoporphyrin Ether trials Research Report on Dihematoporphyrin Ether
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease Porfimer Sodium, Video-Assisted Thoracic Surgery, Photodynamic Therapy - Lung Non-Small Cell Carcinoma, Pleural Disorder | Phase 1 | Terminated | Roswell Park Cancer Institute | 5 | 2022-03-10 | 2026-02-04 |
| Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery Light Dosimetry for Intranoperative Therapy, Photodynamic Therapy, Porfimer Sodium - Malignant Mesothelioma, Non-Small Cell Lung Carcinoma | Phase 1 | Completed | Roswell Park Cancer Institute | 9 | 2021-09-17 | 2026-03-27 |
| Novel Light Delivery Methods for Lung Cancer Photodynamic Therapy - A Pilot Study Porfimer sodium, Ethiodized oil, Novel light delivery methods of photodynamic therapy - Non-small Cell Lung Cancer (NSCLC), Lung Metastasis | Early Phase 1 | Unknown | Taoyuan General Hospital | 3 | 2021-03-01 | 2021-02-15 |
| Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer Porfimer Sodium, Ultrasound-Guided Transbronchial Needle-Delivered Interstitial Photodynamic Therapy - Locally Advanced Lung Carcinoma, Non-Small Cell Lung Carcinoma | Phase 1 / Phase 2 | Completed | Roswell Park Cancer Institute | 19 | 2020-02-12 | 2026-05-14 |
| Porfimer Sodium Interstitial Photodynamic Therapy With or Without Standard of Care Chemotherapy in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer Nivolumab, Porfimer Sodium, Interstitial Illumination Photodynamic Therapy - Recurrent Head and Neck Carcinoma, Locally Advanced Head and Neck Carcinoma | Phase 1 | Terminated | Roswell Park Cancer Institute | 5 | 2019-07-10 | 2025-03-11 |
| Safety of PDT-Photofrin® Prior to Lung Surgery Porfimer Sodium, Fiber optic - Lung Cancer, Lung Cancer Metastatic | Phase 1 | Completed | Concordia Laboratories Inc. | 10 | 2017-08-14 | 2020-01-13 |
| Feasibility Study of Using Navigational Bronchoscopy to Perform PDT-Photofrin® in Unresectable Peripheral Lung Cancer Porfimer sodium, Fiber optic - Non-small Cell Lung Cancer (NSCLC), Lung Metastasis | Phase 1 | Completed | Concordia Laboratories Inc. | 5 | 2017-01-26 | 2020-03-04 |
| Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer photosensitizer(photofrin), 630 nm laser irradiation (DIOMED) - Stage I Esophageal Adenocarcinoma, Stage II Esophageal Adenocarcinoma | Phase 3 | Unknown | The First Affiliated Hospital of Henan University of Science and Technology | 40 | 2015-10-01 | 2015-12-11 |
| Photodynamic Therapy During Surgery in Treating Patients With Pleural Malignancy porfimer sodium, therapeutic conventional surgery, photodynamic therapy - Stage III Malignant Mesothelioma, Stage IIIB Non-small Cell Lung Cancer | Not applicable | Withdrawn | Ohio State University Comprehensive Cancer Center | 2014-09-04 | 2019-03-21 | |
| Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma Photodynamic Therapy, Radical Pleurectomy, Chemotherapy - Epitheliod Malignant Pleural Mesothelioma | Phase 2 | Active not recruiting | Abramson Cancer Center at Penn Medicine | 52 | 2014-06-02 | 2025-12-26 |
| Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer Laboratory Biomarker Analysis, Photodynamic Therapy, Porfimer Sodium - Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Laryngeal Verrucous Carcinoma | Phase 2 | Terminated | Roswell Park Cancer Institute | 3 | 2014-04-01 | 2017-10-11 |
| Ultrasound-Guided Photodynamic Therapy With Photofrin & Gemcitabine for Patients With Locally Advanced Pancreatic Cancer porfimer sodium, endoscopic ultrasonography, photodynamic therapy - Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas | Phase 1 | Completed | John DeWitt | 12 | 2013-04-19 | 2018-12-13 |
| Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors Photofrin (porfimer sodium) & photodynamic therapy. - Brain Tumor, Recurrent | Phase 1 | Completed | Harry T Whelan, MD | 5 | 2013-03-01 | 2019-02-25 |
| Safety and Efficacy of Photodynamic Therapy for Bile Duct Invasion of Hepatocellular Carcinoma Photofrin - Hepatocellular Carcinoma, Obstructive Jaundice | Not applicable | Completed | Samsung Medical Center | 11 | 2009-09-01 | 2015-11-20 |
| Photodynamic Therapy Using Porfimer Sodium in Treating Patients With Non-Small Cell Lung Cancer And Bronchial Disease porfimer sodium, bronchoscopy - Lung Cancer | Completed | Ohio State University Comprehensive Cancer Center | 35 | 2008-12-01 | 2018-07-05 | |
| Biliary Stenting With or Without Photodynamic Therapy in Treating Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors That Cannot Be Removed by Surgery porfimer sodium, biliary stenting - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 3 | Completed | University College, London | 92 | 2007-07-01 | 2013-02-20 |
| Endoscopic Therapy of Early Cancer in Barretts Esophagus Endoscopic Mucosal Resection, Photodynamic Therapy - Early Stage Esophageal Adenocarcinoma, Barrett Esophagus | Phase 2 | Completed | Mayo Clinic | 73 | 2005-09-01 | 2015-12-24 |
| High Light and Low Light Dose PDT in Glioma porfimer sodium, adjuvant therapy, conventional surgery - Brain and Central Nervous System Tumors | Phase 3 | Completed | Case Comprehensive Cancer Center | 1 | 2005-03-01 | 2010-06-11 |
| Sequential Whole Bladder Photodynamic Therapy (WBPDT) in the Management of Superficial Bladder Cancer Whole bladder laser light treatment as an alternative to radical cystectomy, Photofrin - Superficial Bladder Cancer | Phase 1 / Phase 2 | Completed | North Florida/South Georgia Veterans Health System | 22 | 2005-02-01 | 2012-10-26 |
| Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura chemotherapy, porfimer sodium, immunohistochemistry staining method - Lung Cancer, Metastatic Cancer | Phase 2 | Terminated | Abramson Cancer Center at Penn Medicine | 9 | 2004-11-01 | 2020-11-24 |
Showing 20 of 28. Sign in to see all of them.
Carcinoma, Non-Small-Cell Lung (8) · Lung Neoplasms (5) · Astrocytoma (3) · Bile Duct Neoplasms (3) · Brain Neoplasms (3) · Gallbladder Neoplasms (3) · Glioblastoma (3) · Head and Neck Neoplasms (3) · Mesothelioma, Malignant (3) · Squamous Cell Carcinoma of Head and Neck (3) · Central Nervous System Neoplasms (2) · Glioma (2) · Gliosarcoma (2) · Laryngeal Neoplasms (2) · Mouth Neoplasms (2)
Roswell Park Cancer Institute (9) · Abramson Cancer Center at Penn Medicine (2) · Concordia Laboratories Inc. (2) · Ohio State University Comprehensive Cancer Center (2) · Case Comprehensive Cancer Center (1) · Colorado Health Foundation (1) · Harry T Whelan, MD (1) · John DeWitt (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · North Florida/South Georgia Veterans Health System (1) · Samsung Medical Center (1) · Taoyuan General Hospital (1) · The First Affiliated Hospital of Henan University of Science and Technology (1)
United States (23) · Canada (3) · China (1) · South Korea (1) · United Kingdom (1)
Keith Cengel, MD, PhD (2) · Caihong Dong, Master (1) · Erin O'Neil (1) · Francisco Civantos, Jr., MD (1) · Fred W. Hetzel, PhD, JD (1) · Gailin Wang, Bachelor (1) · Hans Gerdes, MD (1) · Harry T Whelan, MD (1) · Hassan Arshad (1) · Hector R. Nava, MD, FACS (1) · James Farrell, MD (1) · Jeff Knipstein, MD (1) · John M DeWitt, MD (1) · Kenneth K. Wang, M.D. (1) · Kimberly Wooten, MD (1)
PMID 14688713, PMID 19687399, PMID 23055220, PMID 29732193, PMID 30222972, PMID 32802440, PMID 39838651
P01CA055791 (1), P30CA008748 (1), P30CA016056 (1), P30CA043703 (1), R01CA111603 (1), R01CA193610 (1), R44CA265656 (1)