7 completed, 7 unknown, 3 recruiting, 2 terminated. 7 Phase 2, 6 Phase 1, 4 Not applicable, 3 Phase 4, 2 Phase 3.
Follow Peripheral Nerve Injury: new trials by email Literature Review of Peripheral Nerve Injury trials Research Report on Peripheral Nerve Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction Avance Nerve Graft, Sural nerve autograft - Peripheral Nerve Injury, Peripheral Nerve Discontinuity | Phase 4 | Recruiting | Axogen Corporation | 178 | 2026-06-11 | 2026-11-12 |
| 4-AP Peripheral Nerve Crossover Trial 4-Aminopyridine, Placebo - Peripheral Nerve Injury, Crush Injury | Phase 2 | Recruiting | University of Arizona | 68 | 2025-04-21 | 2025-08-05 |
| Mirror Therapy Combined With Contralaterally Controlled Functional Electrical Stimulation for Peripheral Nerve Injury mirror therapy, contralaterally controlled functional electrical stimulation, conventional physiotherapy - Peripheral Nerve Injury | Not applicable | Completed | National Taiwan University Hospital | 7 | 2024-03-29 | 2026-01-14 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI) Autologous Human Schwann Cell - Peripheral Nerve Injury | Phase 1 | Recruiting | W. Dalton Dietrich | 30 | 2023-05-04 | 2026-09-29 |
| Polyethylene Glycol to Improve Sensation Following Digital Nerve Laceration Polyethylene Glycol 3350, Normal Saline - Peripheral Nerve Injury, Nerve Injury | Phase 1 / Phase 2 | Withdrawn | Nova Scotia Health Authority | 2020-06-26 | 2024-01-05 | |
| Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function Polyethylene glycol (PEG) - Peripheral Nerve Injury | Phase 1 | Completed | Vanderbilt University Medical Center | 45 | 2019-09-19 | 2026-06-15 |
| Extracorporal Shock Wave Treatment to Improve Nerve Regeneration MTS Medical UG Orthogold 100, Sham - Peripheral Nerve Injury | Not applicable | Unknown | Ludwig Boltzmann Gesellschaft | 60 | 2017-04-18 | 2021-09-05 |
| Cortical Effects of Peripheral Nerve Injury At Birth Peripheral Nerve Injury | Unknown | Gazi University | 15 | 2016-10-01 | 2016-08-12 | |
| The Influence of Sensory Phenotype on the Risk of Developing Neuropathic Pain QST, Questionnaires - Neuropathic Pain, Polyneuropathy | Unknown | University of Kiel | 1500 | 2016-04-01 | 2016-01-28 | |
| Safety and Efficacy Study of Neovasculgen (Pl-VEGF165) Gene Therapy in Patients With Peripheral Nerve Injury Neovasculgen - Peripheral Nerve Injury | Phase 1 / Phase 2 | Unknown | Artgen Biotech | 45 | 2015-04-01 | 2015-02-02 |
| Micro-Electrodes Implanted in a Human Nerve Utah Slanted Electrode Array - Amputations, Peripheral Nerve Injury | Not applicable | Terminated | University of Utah | 11 | 2013-04-01 | 2022-07-07 |
| Needle Nerve Contact in Ultrasound Guided Femoral Block Needle placement - Peripheral Nerve Injury | Not applicable | Unknown | Hospital Clinic of Barcelona | 44 | 2011-11-01 | 2012-03-15 |
| Study of Possible Changes in QST After Application of Capsaicin on Patients With Peripheral Neuropathic Pain quantitative sensory testing (QST) - Peripheral Nerve Injury, Postherpetic Neuralgia | Completed | Ruhr University of Bochum | 20 | 2011-04-01 | 2012-12-20 | |
| Efficacy of Etoricoxib on Peripheral Hyperalgesia Etoricoxib, placebo - Causalgia, Polyneuropathy | Phase 2 | Terminated | Ruhr University of Bochum | 9 | 2011-02-01 | 2012-08-24 |
| Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain Oxcarbazepine - Polyneuropathy, Peripheral Nerve Injury | Phase 4 | Completed | Søren H. Sindrup | 117 | 2011-02-01 | 2014-05-05 |
| Enhancement of Functional Recovery After Peripheral Nerve Injury With Tacrolimus Tacrolimus - Peripheral Nerve Injury | Phase 1 / Phase 2 | Withdrawn | Washington University School of Medicine | 2010-08-01 | 2018-02-13 | |
| Study of Nerve Reconstruction Using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer Processed Human Nerve Tissue Scaffold - Peripheral Nerve Injury, Prostate Cancer | Phase 4 | Completed | Axogen Corporation | 12 | 2009-08-01 | 2024-08-12 |
| Study of Capsaicin Patch for the Management of Peripheral Neuropathic Pain CAPNP, 50 ug/cm2 capsaicin patch, CAPNP, 100 ug/cm2 capsaicin patch, 0.075% capsaicin cream - Peripheral Nerve Injury, Postherpetic Neuralgia | Phase 1 / Phase 2 | Completed | Samyang Biopharmaceuticals Corporation | 60 | 2009-02-01 | 2017-05-01 |
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Peripheral Nerve Injuries (21) · Neuralgia (5) · Neuralgia, Postherpetic (4) · Polyneuropathies (3) · Agnosia (2) · Chronic Pain (2) · Marijuana Abuse (2) · Pain (2) · Pain, Postoperative (2) · Peripheral Nervous System Diseases (2) · Somatoform Disorders (2) · Causalgia (1) · Crush Injuries (1) · Prostatic Neoplasms (1) · Radiculopathy (1)
Nervous System Diseases (21) · Neuromuscular Diseases (21) · Wounds and Injuries (21) · Trauma, Nervous System (20) · Peripheral Nervous System Diseases (19) · Neurologic Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Pain (5) · Chemically-Induced Disorders (2) · Mental Disorders (2) · Neuralgia (2) · Neurobehavioral Manifestations (2) · Pathologic Processes (2) · Perceptual Disorders (2)
4-Aminopyridine (1) · Etoricoxib (1) · Mirror Movement Therapy (1) · Oxcarbazepine (1) · Polyethylene Glycols (1) · Saline Solution (1) · Surveys and Questionnaires (1) · Tacrolimus (1) · polyethylene glycol 3350 (1)
Apurano Pharmaceuticals GmbH (2) · Axogen Corporation (2) · Ruhr University of Bochum (2) · Artgen Biotech (1) · Gazi University (1) · Hospital Clinic of Barcelona (1) · Isfahan University of Medical Sciences (1) · Ludwig Boltzmann Gesellschaft (1) · National Taiwan University Hospital (1) · Nova Scotia Health Authority (1) · Samyang Biopharmaceuticals Corporation (1) · Søren H. Sindrup (1) · University of Arizona (1) · University of Kiel (1) · University of Utah (1)
United States (7) · Germany (4) · Austria (1) · Denmark (1) · Iran (1) · South Korea (1) · Spain (1) · Taiwan (1)
Admir Hadzic, Prof Dr (1) · Ana Ruiz, MD (1) · Christoph Maier, Dr.med (1) · Christoph Maier, Prof.Dr.med (1) · Douglas Hutchinson (1) · John Elfar, MD (1) · Joseph J Smith, MD (1) · Julia Martinez-Ocon, MD (1) · Maria J Carretero, MD (1) · R. Glenn Gaston, MD (1) · Thomas H Tung, MD (1) · W. Dalton Dietrich, MD (1) · Wesley Thayer, MD (1)
2009 (1), R01NS111293 (1)