9 completed, 5 recruiting, 4 unknown, 3 terminated. 11 Not applicable, 3 Phase 2, 2 Phase 4, 1 Phase 1.
Follow Parkinson Disease Dementia: new trials by email Literature Review of Parkinson Disease Dementia trials Research Report on Parkinson Disease Dementia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Visual Hallucinations in Lewy Body Diseases Behavioral Tasks, MRI/MEG Scans - Lewy Body Disease, Lewy Body Dementia | Recruiting | NYU Langone Health | 234 | 2026-09-15 | 2026-09-30 | |
| Monoamine Oxidase B PET/CT in Various MAO-B-Related Disease Diagnostic Test: 18F-FPyCO/SMBT-1 - Parkinson Disease, Parkinson Disease Dementia | Recruiting | Tianjin Medical University | 200 | 2026-06-25 | 2026-09-08 | |
| Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia Syn-One skin biopsy, Multi modal MRI, Assessment of dynamic EEG features over 48-hour periods across all study aims - Dementia With Lewy Bodies, Parkinson Disease Dementia | Phase 4 | Recruiting | Virginia Commonwealth University | 120 | 2025-12-08 | 2026-03-06 |
| Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments Tributyrin, Placebo - Parkinson Disease, Parkinson Disease Dementia | Phase 1 / Phase 2 | Recruiting | Prabesh Kanel | 45 | 2025-11-07 | 2025-11-12 |
| To Evaluate the Safety of DBS in Patients With Primary Parkinson's Disease Implant device - Parkinson Disease Dementia | Not applicable | Unknown | Jiangsu CED Medtech Co., Ltd | 3 | 2024-07-01 | 2024-07-10 |
| PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia Peer Mentor Support and Caregiver Education, Caregiver Education - Lewy Body Dementia, Parkinson Disease Dementia | Not applicable | Active not recruiting | Rush University Medical Center | 622 | 2024-05-13 | 2026-03-20 |
| SHARPEN - Parkinson's Disease Dementia Non-invasive brainstem stimulation - Parkinson Disease Dementia | Not applicable | Terminated | Scion NeuroStim | 9 | 2024-05-08 | 2025-05-09 |
| Family Caregiver Online Survey (Dementia and Swallowing Difficulties) Dementia, Dysphagia | Completed | University of Oregon | 219 | 2023-11-07 | 2025-12-18 | |
| Environmental and Reproductive Health Risk for Lewy Body Dementia Survey - Lewy Body Dementia, Parkinson Disease Dementia | Unknown | University of California, San Diego | 225 | 2023-08-01 | 2024-07-03 | |
| Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Ketones Ketone Ester (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate - Parkinson Disease, Lewy Body Dementia | Not applicable | Terminated | University of Michigan | 16 | 2023-03-09 | 2025-02-12 |
| A Study of Caregiver Connections Via Technology in Dementia Algorithm, Random Match - Caregiver Stress, Dementia | Not applicable | Completed | Mayo Clinic | 420 | 2023-02-06 | 2026-10-19 |
| Comparison Between Parkinson's Disease and Parkinson's Dementia Complex (Genetically,Clinical and Electrophysiological) Cortical excitability using transcranial magnetic stimulation - Parkinson Disease Dementia, Parkinson Disease | Unknown | Assiut University | 40 | 2022-11-01 | 2023-03-08 | |
| A Study to Evaluate Caregiver Connections Via Technology for Patients With Alzheimer's and Other Types of Dementia Algorithm, Random Match - Caregiver Stress, Dementia | Not applicable | Withdrawn | Mayo Clinic | 2022-09-01 | 2022-11-17 | |
| Community Outreach for Palliative Engagement -- Parkinson Disease Parkinson Disease Standard Care, Online Community-Supported Palliative Care - Parkinson Disease Dementia, Parkinson Disease | Not applicable | Active not recruiting | University of Rochester | 632 | 2022-04-26 | 2026-03-06 |
| ATH-1017 Treatment in Subjects With Parkinson's Disease Dementia or Dementia With Lewy Bodies (SHAPE Trial) ATH-1017, Placebo - Parkinson Disease Dementia, Dementia With Lewy Bodies | Phase 2 | Terminated | LeonaBio | 28 | 2022-01-20 | 2025-03-04 |
| Sing for Your Saunter - Dementia Supplement Mentally Singing, Listening to music - Parkinson Disease, Parkinson Disease Dementia | Not applicable | Completed | Washington University School of Medicine | 17 | 2021-04-19 | 2025-01-09 |
| Dementias and Microbiota Composition: Is Possible to Revert the Dementia Symptoms Reverting the Microbiota Composition? No intervention, Probiotic supplement - Dementia Alzheimers, Dementia With Lewy Bodies | Unknown | University Rovira i Virgili | 240 | 2021-04-16 | 2023-07-13 | |
| The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment Vespa software - Neurodegenerative Diseases, Cognitive Decline | Not applicable | Completed | IRCCS Centro Neurolesi Bonino Pulejo | 60 | 2021-03-01 | 2024-03-08 |
| Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia Peer mentor support and caregiver intervention, Focus group to provide feedback on educational materials and mentoring program - Lewy Body Disease, Parkinson Disease Dementia | Not applicable | Completed | Rush University Medical Center | 87 | 2020-11-02 | 2023-01-25 |
| OLE Study for Patients With Parkinson's Disease With Dementia Enrolled in Study ANAVEX2-73-PDD-001 ANAVEX2-73 - Parkinson Disease Dementia | Phase 2 | Completed | Anavex Life Sciences Corp. | 132 | 2019-10-10 | 2022-08-01 |
Showing 20 of 24. Sign in to see all of them.
Lewy Body Disease (13) · Parkinson Disease (10) · Alzheimer Disease (6) · Dementia (5) · Cognitive Dysfunction (4) · Caregiver Burden (2) · Dementia, Vascular (2) · Frontotemporal Dementia (2) · Parkinsonian Disorders (2) · Pick Disease of the Brain (2) · Corticobasal Degeneration (1) · Deafness, Autosomal Recessive 39 (1) · Deglutition Disorders (1) · Hallucinations (1) · Ketosis (1)
Brain Diseases (20) · Central Nervous System Diseases (20) · Nervous System Diseases (20) · Basal Ganglia Diseases (19) · Movement Disorders (19) · Neurodegenerative Diseases (19) · Synucleinopathies (19) · Parkinsonian Disorders (17) · Mental Disorders (15) · Neurocognitive Disorders (15) · Dementia (9) · Tauopathies (7) · Cognition Disorders (4) · Frontotemporal Lobar Degeneration (4) · Metabolic Diseases (3)
Algorithms (2) · Amyloid beta-Protein Precursor (1) · Drug Implants (1) · Neuropsychological Tests (1) · Surveys and Questionnaires (1) · tetrahydro-N, N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (1) · tributyrin (1)
Mayo Clinic (2) · Rush University Medical Center (2) · Anavex Life Sciences Corp. (1) · Assiut University (1) · IRCCS Centro Neurolesi Bonino Pulejo (1) · Jiangsu CED Medtech Co., Ltd (1) · LeonaBio (1) · NYU Langone Health (1) · Prabesh Kanel (1) · Scion NeuroStim (1) · Tianjin Medical University (1) · University Hospital, Strasbourg, France (1) · University Rovira i Virgili (1) · University of California, San Diego (1) · University of Maryland, Baltimore (1)
United States (16) · Spain (2) · Australia (1) · China (1) · Egypt (1) · France (1) · Italy (1)
Jori E Fleisher, MD MSCE (2) · Julie Fields, PhD, LP (2) · Benzi Kluger, MD (1) · Biyu He, PhD (1) · Ece Bayram, MD, PhD (1) · Francesco Corallo, PSY (1) · Gammon Earhart (1) · Karen Fredriksen-Goldsen, PhD (1) · Kevin Kramer, PhD (1) · Margarita Torrente, Dr (1) · Matthew Barrett (1) · Nicolaas Bohnen, MD (1) · Prabesh Kanel, PhD (1) · Rainer von Coelln, Dr. med. (1)
PMID 37385161, PMID 41387197, PMID 42778090
R44AG065088 (2), P30AG028747 (1), P30AG064200 (1), R01AG055488 (1), R01AG079128 (1), R01NS142622 (1), R01NS148898 (1), R43NS132653 (1)