9 completed, 2 recruiting, 2 unknown, 2 withdrawn. 7 Not applicable, 3 Phase 3, 1 Early Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Not yet recruiting 1, Withdrawn 1 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Parathyroid Adenoma: new trials by email Literature Review of Parathyroid Adenoma trials Research Report on Parathyroid Adenoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-Making Near-Infrared Parathyroid Tissue Sensor Imaging (PTS), Rim-Preservation Technique, En-bloc Resection Technique - Hyperparathyroidism, Primary, Parathyroid Neoplasms | Not applicable | Not yet recruiting | Fujian Medical University | 120 | 2025-07-01 | 2025-06-29 |
| PTeye in Parathyroid Adenoma parathyroidectomy - Parathyroid Adenoma | Recruiting | Aristotle University Of Thessaloniki | 50 | 2025-03-28 | 2025-04-06 | |
| 99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT 18Fluorocholine - Parathyroid Adenoma | Phase 2 / Phase 3 | Recruiting | Andrei Iagaru | 100 | 2023-09-27 | 2026-06-24 |
| Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy Parathyroid Eye (PTeye) - Parathyroid Diseases, Parathyroid Dysfunction | Not applicable | Completed | University of California, San Francisco | 79 | 2022-01-10 | 2025-12-15 |
| Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy PTeye, Standard of Care - Parathyroid Adenoma, Parathyroid Neoplasms | Not applicable | Completed | University of Michigan | 160 | 2021-12-01 | 2025-08-27 |
| Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy NIRAF Detection Technology - Parathyroid Adenoma, Parathyroid Neoplasms | Not applicable | Completed | Vanderbilt-Ingram Cancer Center | 160 | 2020-03-13 | 2024-05-13 |
| Exparel Injection Effect on Postoperative Opioid Usage Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine, Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine - Thyroid, Parathyroid Adenoma | Early Phase 1 | Unknown | University of Missouri-Columbia | 100 | 2019-09-30 | 2024-07-29 |
| Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention MIBI scintigraphy, F18-choline PET - Parathyroid Adenoma, Hyperparathyroidism | Phase 3 | Completed | Centre Francois Baclesse | 59 | 2019-09-19 | 2023-08-01 |
| Preoperational Fine Needle Aspiration of Pathological Parathyroid Gland pre operative parathyroid hormone level measurement, pre operative parathyroid cytology, parathyroid hormone level measurement - Parathyroid Adenoma, Hypercalcemia | Not applicable | Withdrawn | HaEmek Medical Center, Israel | 2018-06-09 | 2022-04-11 | |
| Minimizing Narcotic Analgesics After Endocrine Surgery Acetaminophen 500Mg Cap, Tylenol #3 Oral Tablet, Tramadol - Thyroid Cancer, Thyroid Nodule | Phase 4 | Completed | Minerva A Romero Arenas | 126 | 2018-03-09 | 2021-05-11 |
| Treatment of Primary Hyperparathyroidism With Denosumab and Cinacalcet. Cinacalcet 30 mg Tablet, Denosumab Inj 60 mg/ml, Placebo tablets - Primary Hyperparathyroidism, Parathyroid Adenoma | Phase 3 | Completed | Peter Vestergaard | 46 | 2017-03-01 | 2021-05-25 |
| Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid Surgery Conventional (dual-phase) SPECT/CT, Multi-phase SPECT/CT, Conventional minimally-invasive radio-guided parathyroidectomy - Primary Hyperparathyroidism, Thyroid Disease | Not applicable | Completed | University Hospital Ostrava | 100 | 2016-05-01 | 2022-12-07 |
| The Feasibility of Bilateral Intermediate Cervical Plexus Block for Thyroidectomy/Parathyroidectomy Bilateral intermediate cervical plexus block - Parathyroid Adenoma, Thyroid Nodule | Completed | Mahidol University | 19 | 2016-03-10 | 2021-06-01 | |
| The Utility of 18F-fluorocholine PET/CT in the Imaging of Parathyroid Adenomas We assessed sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid tissue in patients with primary hyperparathyroidism - Hyperparathyroidism, Parathyroid Adenoma | Not applicable | Completed | Military Institute od Medicine National Research Institute | 65 | 2016-01-01 | 2020-09-30 |
| Evaluation of a New CZT System Parathyroid Adenoma, Thyroid Adenoma | Unknown | Tel-Aviv Sourasky Medical Center | 100 | 2010-03-01 | 2010-03-10 | |
| Multicenter Registry Comparing Preoperative Imaging for Primary Hyperparathyroidism Parathyroid Adenoma | Withdrawn | Duke University | 2015-09-21 |
Parathyroid Neoplasms (16) · Hyperparathyroidism, Primary (6) · Hypercalcemia (4) · Hyperparathyroidism (3) · Parathyroid Diseases (3) · Thyroid Diseases (3) · Thyroid Neoplasms (2) · Thyroid Nodule (2) · Adenoma (1) · Agnosia (1) · Endocrine Gland Neoplasms (1) · Goiter (1) · Hypocalcemia (1) · Neoplasms, Glandular and Epithelial (1) · Opioid-Related Disorders (1)
Endocrine System Diseases (16) · Head and Neck Neoplasms (16) · Neoplasms (16) · Neoplasms by Site (16) · Endocrine Gland Neoplasms (15) · Parathyroid Diseases (13) · Calcium Metabolism Disorders (5) · Hyperparathyroidism (5) · Metabolic Diseases (5) · Nutritional and Metabolic Diseases (5) · Water-Electrolyte Imbalance (5) · Thyroid Diseases (2) · Chemically-Induced Disorders (1) · Mental Disorders (1) · Narcotic-Related Disorders (1)
Acetaminophen (1) · Capsules (1) · Cinacalcet (1) · Congresses as Topic (1) · Denosumab (1) · Parathyroidectomy (1) · Sodium Chloride (1) · Standard of Care (1) · Tablets (1) · Tramadol (1) · acetaminophen, codeine drug combination (1)
Andrei Iagaru (1) · Aristotle University Of Thessaloniki (1) · Centre Francois Baclesse (1) · Duke University (1) · Fujian Medical University (1) · HaEmek Medical Center, Israel (1) · Mahidol University (1) · Military Institute od Medicine National Research Institute (1) · Minerva A Romero Arenas (1) · Peter Vestergaard (1) · Tel-Aviv Sourasky Medical Center (1) · University Hospital Ostrava (1) · University of California, San Francisco (1) · University of Michigan (1) · University of Missouri-Columbia (1)
United States (6) · Israel (2) · China (1) · Czechia (1) · Denmark (1) · France (1) · Greece (1) · Thailand (1)
Andrei Iagaru, MD (1) · Andrzej Mazurek, MD, PhD (1) · Carmen C Solorzano, MD, FACS (1) · Chrysa Papadopoulou (1) · Dror Ashkenazi, M.D (1) · Einat Even Sapir, PhD, MD (1) · Henry A Reinhart, MD (1) · Julius Simoni Leere, MD (1) · Minerva A Romero Arenas, MD, MPH (1) · Moysis Moysidis, Dr (1) · Paul Gauger (1) · Peter Vestergaard, DMSc (1) · Quan-Yang Duh, MD, FACS (1) · Samuel K Snyder, MD (1)
PMID 40668552, PMID 16125070, PMID 17131394, PMID 19017880, PMID 19216305, PMID 22089066, PMID 24227357, PMID 24639923, PMID 27532368, PMID 2774445, PMID 31919634, PMID 32333877, PMID 33413316, PMID 38900416
R01CA212147 (3), 2016 (1)