25 completed, 3 recruiting, 3 unknown, 1 active not recruiting. 22 Not applicable, 3 Early Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 22 | Completed 18, Recruiting 2, Enrolling by invitation 1, Unknown 1 |
| Early Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
Follow Pain Threshold: new trials by email Literature Review of Pain Threshold trials Research Report on Pain Threshold
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Remifentanil on the Objectively Measured Pressure Pain Threshold Pressure pain theshold measured under remifentanil (ultiva®) infusion, Postoperative PCA IV morphine (Sterop®) consumption and adverse events history - Pain Threshold, Surgery | Not applicable | Enrolling by invitation | Université Libre de Bruxelles | 40 | 2026-01-26 | 2026-05-05 |
| Acute Effects of LLLT on Pain Threshold and Pain Tolerance Low-Level Laser Therapy (LLLT), Sham LLLT - Pain Threshold, Pain Tolerance | Not applicable | Completed | European University of Lefke | 62 | 2025-12-15 | 2026-07-02 |
| A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder AFA-281 - Alcohol Abuse, Alcohol Abuse/addiction | Phase 2 | Not yet recruiting | Afasci Inc | 36 | 2025-10-01 | 2024-11-29 |
| Pharmacodynamic Study of 100mg Suzegtrigine vs Placebo in Healthy Male Adults suzetrigine 100mg, Placebo - Pain Detection, Pain Threshold | Early Phase 1 | Completed | Latigo Biotherapeutics | 20 | 2025-06-04 | 2025-07-03 |
| Correlation Between Pain Threshold and Analgesic Consumption in Transvaginal Oocyte Aspiration Patients Pain Threshold, Conscious Sedation | Active not recruiting | Burcu ayvazoğlu | 30 | 2025-04-28 | 2025-12-03 | |
| Does Boredom Affect Mechanical Pain Thresholds Emotional intervention - Pain Threshold, Healthy | Not applicable | Completed | Linnaeus University | 120 | 2025-03-25 | 2025-04-29 |
| Replication Study: Reducing Pain With Focused Music Listening Music Listening, Silence Control, Active Sensorimotor Synchronization - Pain, Pain Management | Not applicable | Completed | University of Bergen | 61 | 2025-03-01 | 2025-05-07 |
| The Pain Perception Threshold in Attention Deficit Disorder With Hyperactivity Pain perception threshold - Pain Threshold, Attention Deficit Disorder With Hyperactivity (ADHD) | Completed | Sultan 1. Murat State Hospital | 84 | 2025-02-16 | 2025-12-30 | |
| Perception of Pain During Gender Affirming Hormone Therapy Quantitative Sensory Testing, Patient Health Questionnaire 9, Hormone concentrations - Transgender Persons, Pain Threshold | Recruiting | Medical University of Vienna | 40 | 2024-12-01 | 2025-08-29 | |
| Pharmacodynamic Study of 300mg Pregabalin vs Placebo in Healthy Male Adults pregabalin 300 mg, Placebo - Pain Detection, Pain Threshold | Early Phase 1 | Completed | Latigo Biotherapeutics | 20 | 2024-10-07 | 2025-05-04 |
| Comparative Effects of Myofascial Induction Therapy Versus Gastrocnemius Pressure Release Treatment on Trigger Point Pressure Pain Threshold in Proximal Muscles and Ankle Range of Motion. Myofascial induction in gastrocnemius, Preassure release - Pain Threshold, Myofascial Trigger Point | Not applicable | Completed | Mayuben Private Clinic | 13 | 2024-07-22 | 2024-08-06 |
| Effects of Myofascial Induction Pressure Pain Threshold in Trigger Points of the Proximal Muscles of Gastrocnemius Myofascial induction in gastrocnemius muscle - Myofascial Trigger Point, Gastrocnemius Muscle | Not applicable | Completed | Mayuben Private Clinic | 13 | 2024-07-22 | 2024-07-30 |
| Session-Order Sensitivity of TS and OA in a Capsaicin Crossover Model Topical 0.075% capsaicin cream (Zostrix), Topical vehicle lotion (Lubriderm) - Hyperalgesia, Pain Perception | Not applicable | Completed | University of Guelph | 16 | 2024-05-01 | 2026-06-04 |
| ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery Acupuncture group - Acupuncture Analgesia, Acupuncture | Not applicable | Recruiting | Fondazione IRCCS Policlinico San Matteo di Pavia | 80 | 2024-04-10 | 2025-08-14 |
| Cervical Muscle Endurance and Pressure Pain Threshold in University Students With TMD: A Case-Control Study Temporomandibular Disorder (TMD), Pain Threshold | Completed | Kırıkkale University | 60 | 2024-04-10 | 2026-02-12 | |
| Predictors of Pressure Pain Thresholds Office Worker, Myofascial Pain Syndrome (Upper Trapezius) | Completed | Dokuz Eylul University | 67 | 2023-11-04 | 2026-10-29 | |
| The Effect of Stretching Intensity on Pain Sensitivity Static stretching - Pain Threshold, Stretching | Not applicable | Completed | University College of Northern Denmark | 31 | 2023-08-20 | 2024-05-09 |
| Influence of Extracorporeal Shockwave Therapy in Patients of Mechanical Neck Pain Extracorporeal Shockwave therapy, Exercise - Neck Pain Musculoskeletal, Neck Pain | Not applicable | Completed | Benha University | 52 | 2023-07-01 | 2025-12-05 |
| Mandibular Muscle Energy Technique in Patients With Mandibular Joint Pathology and Bruxism Muscle-energy mandibular technique, Sham technique - Temporomandibular Joint Disorders, Bruxism | Not applicable | Unknown | University of Salamanca | 60 | 2022-04-25 | 2023-05-25 |
| The Effects of Instrument-Assisted Soft Tissue Mobilization in Sedentary Individuals With Hamstring Tightness Exercise - Hamstring Muscle Tightness, Muscle Strength | Not applicable | Completed | Cyprus International University | 51 | 2022-04-11 | 2025-07-29 |
Showing 20 of 34. Sign in to see all of them.
Pain (5) · Pain, Postoperative (3) · Anxiety Disorders (2) · Depression (2) · Temporomandibular Joint Disorders (2) · Acute Pain (1) · Agnosia (1) · Alcoholism (1) · Attention Deficit Disorder with Hyperactivity (1) · Back Pain (1) · Behavior, Addictive (1) · Breast Neoplasms (1) · Bruxism (1) · Diabetes, Gestational (1) · Hyperalgesia (1)
Neurologic Manifestations (14) · Pathological Conditions, Signs and Symptoms (14) · Signs and Symptoms (14) · Pain (7) · Mental Disorders (5) · Musculoskeletal Diseases (4) · Nervous System Diseases (4) · Pathologic Processes (4) · Behavior (3) · Joint Diseases (3) · Muscular Diseases (3) · Postoperative Complications (3) · Behavioral Symptoms (2) · Chemically-Induced Disorders (2) · Craniomandibular Disorders (2)
Exercise (2) · Capsaicin (1) · Dronabinol (1) · Economics (1) · Extracorporeal Shockwave Therapy (1) · Low-Level Light Therapy (1) · Manipulation, Spinal (1) · Muscle Stretching Exercises (1) · Plyometric Exercise (1) · Pregabalin (1) · RE1-silencing transcription factor (1)
University College of Northern Denmark (4) · Latigo Biotherapeutics (2) · Mayuben Private Clinic (2) · Afasci Inc (1) · Ain Shams University (1) · Benha University (1) · Burcu ayvazoğlu (1) · Columbia University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Cornell University (1) · Cyprus International University (1) · Dokuz Eylul University (1) · Dow University of Health Sciences (1) · European University of Lefke (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1)
Turkey (Türkiye) (6) · Denmark (5) · United States (4) · Spain (3) · Egypt (2) · New Zealand (2) · Austria (1) · Belgium (1) · Canada (1) · Cyprus (1) · France (1) · Italy (1) · Norway (1) · Pakistan (1) · Poland (1)
Dorte Drachman, Msc. (2) · Anna N Szumilewicz, Assoc. Prof. (1) · Anthony Davis, MBChB (1) · Binnaz Bozkurt Akpulat, MSc. (1) · Christine Brefel-Courbon, MD (1) · Dorte Drachmann, Msc. (1) · Fathy Tash, MD (1) · Henrik Kehlet, MD Ph.D DMSc (1) · Lara Ray, MD (1) · Margaret Haney, Ph.D (1)
PMID 21399855, PMID 24217134, PMID 24358863, PMID 24828475, PMID 25811029, PMID 26592226, PMID 27390432, PMID 28349028, PMID 28912629, PMID 29254664, PMID 32731757, PMID 33845880, PMID 34305648, PMID 34387949, PMID 36550564, PMID 36927595, PMID 38879168, PMID 39110708, PMID 39334218, PMID 39543304
P50DA009236 (1)