3 completed, 2 not yet recruiting, 1 active not recruiting, 1 enrolling by invitation. 10 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 3, Not yet recruiting 2, Active not recruiting 1, Enrolling by invitation 1, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
Follow Osteo Arthritis Knee: new trials by email Literature Review of Osteo Arthritis Knee trials Research Report on Osteo Arthritis Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of GNSC-001 Intra-articular Injection for Knee Osteoarthritis Gene Therapy GNSC-001, Placebo - Knee Arthritis Osteoarthritis, Knee Arthritis, Osteoarthritis | Phase 2 / Phase 3 | Not yet recruiting | Genascence Corporation | 240 | 2027-07-01 | 2026-09-21 |
| Extended Oral Tranexamic Acid After Total Knee Arthroplasty Tranexamic acid, Placebo - Osteo Arthritis Knee, Pain, Postoperative | Phase 3 | Enrolling by invitation | Campbell Clinic | 120 | 2024-09-17 | 2026-08-13 |
| Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis Microfragmented Adipose Tissue derived using the Lipogems® System, Saline Injection - Knee Osteoarthritis, Osteo Arthritis Knee | Phase 3 | Active not recruiting | Lipogems International spa | 173 | 2024-03-15 | 2025-06-12 |
| Comparison Between Intra-articular Infiltrations of PRP, MFAT, and PRP-MFAT in the Treatment of Symptomatic Knee Osteoarthritis. Intra-articular injection of autologous microfat, Intra-articular injection of autologous platelet-rich plasma, Intra-articular injection of autologous microfat and platelet-rich plasma - Osteo Arthritis Knee | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 180 | 2024-02-02 | 2023-10-27 |
| Metformin Safety and Efficacy in Osteoarthritis. Celecoxib 200mg, Metformin - Osteo Arthritis Knee | Phase 3 | Recruiting | Mostafa Bahaa | 70 | 2024-01-30 | 2026-03-13 |
| A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee Retatrutide, Placebo - Obesity, Overweight | Phase 3 | Completed | Eli Lilly and Company | 445 | 2023-08-01 | 2026-01-21 |
| Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis Microfragmented Adipose Tissue, Corticosteroid - Knee Osteoarthritis, Osteo Arthritis Knee | Phase 3 | Completed | Lipogems International spa | 173 | 2022-12-30 | 2025-04-22 |
| Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed Resiniferatoxin, Placebo - Osteoarthritis, Knee, Osteo Arthritis Knee | Phase 3 | Withdrawn | Sorrento Therapeutics, Inc. | 2021-04-01 | 2021-11-09 | |
| Intraarticular Leukocyte-rich and Leukocyte-poor PRP for Osteoarthritis of the Knee Leukocyte-rich platelet-rich plasma, Leukocyte-poor platelet-rich plasma, Corticosteroid - Osteo Arthritis Knee | Phase 2 / Phase 3 | Completed | Queen Savang Vadhana Memorial Hospital, Thailand | 93 | 2020-08-03 | 2023-02-21 |
| Bone Marrow Versus Adipose Autologous Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis bone marrow mesenchymal stem cells, Adipose Mesenchymal stem cells, bone marrow & adipose mesenchymal stem cells injection - Osteo Arthritis Knee | Phase 3 | Unknown | Universidad Catolica Santiago de Guayaquil | 54 | 2020-06-07 | 2020-04-17 |
Osteoarthritis, Knee (4) · Osteoarthritis (2) · Obesity (1) · Overweight (1) · Pain (1) · Pain, Postoperative (1)
Arthritis (5) · Joint Diseases (5) · Musculoskeletal Diseases (5) · Rheumatic Diseases (5) · Osteoarthritis (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Neurologic Manifestations (2) · Body Weight (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1) · Overnutrition (1) · Pain (1) · Pathologic Processes (1) · Postoperative Complications (1)
Adrenal Cortex Hormones (2) · Celecoxib (1) · Metformin (1) · Sodium Chloride (1) · Steroids (1) · Tranexamic Acid (1) · microcrystalline cellulose (1) · resiniferatoxin (1) · retatrutide (1)
Lipogems International spa (2) · Assistance Publique Hopitaux De Marseille (1) · Campbell Clinic (1) · Eli Lilly and Company (1) · Genascence Corporation (1) · Mostafa Bahaa (1) · Queen Savang Vadhana Memorial Hospital, Thailand (1) · Sorrento Therapeutics, Inc. (1) · Universidad Catolica Santiago de Guayaquil (1)
United States (4) · Australia (1) · Canada (1) · Ecuador (1) · Egypt (1) · Mexico (1) · Spain (1) · Thailand (1) · United Kingdom (1)
Carlos A Chiriboga, MD (1) · Christopher Holland, MD, MS (1) · Monica Luchi, MD (1) · Surapol Athiprayul, MD (1)
PMID 11869080, PMID 12081113, PMID 16263424, PMID 1991946, PMID 20603892, PMID 23831631, PMID 24449146, PMID 25035839, PMID 25161985, PMID 25925602, PMID 25944079, PMID 26432430, PMID 27229856, PMID 28012636, PMID 28386761, PMID 30623236, PMID 30632533, PMID 34826301, PMID 35103547
2023 (1)