16 completed, 2 terminated, 1 active not recruiting, 1 recruiting. 5 Phase 3, 4 Phase 4, 3 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 5 |
| Phase 4 | 4 | Completed 4 |
| Not applicable | 3 | Completed 2, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Osteitis Deformans: new trials by email Literature Review of Osteitis Deformans trials Research Report on Osteitis Deformans
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genetic Analysis to Predict the Development of Paget's Disease Paget Disease, Paget Disease of Bone | Active not recruiting | University of Edinburgh | 135 | 2022-01-01 | 2026-07-01 | |
| Study for Women and Men With Hormone-receptor Positive Locally Advanced or Metastatic Breast Cancer ribociclib, letrozole, goserelin - Advanced Metastatic Breast Cancer | Phase 3 | Completed | Novartis Pharmaceuticals | 502 | 2016-10-24 | 2021-10-11 |
| Pathophysiology of Paget's Disease of Bone Paget's Disease of Bone | Completed | Johns Hopkins University | 11 | 2016-04-01 | 2024-11-20 | |
| Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma DCE-MRI, DW-MRI, MT-MRI, and CEST-MRI - Osteosarcoma, Paget's Disease | Not applicable | Terminated | Vanderbilt-Ingram Cancer Center | 6 | 2013-03-01 | 2017-05-08 |
| Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer Videoscopic procedure, Open, traditional approach - Melanoma, Merkel Cell Carcinoma | Not applicable | Completed | Emory University | 29 | 2009-06-01 | 2015-05-06 |
| Efficacy and Safety of Single Dose of 5 mg Zoledronic Acid in Chinese Patients With Paget's Disease of Bone (PDB) Zoledronic acid - Paget's Disease of Bone | Phase 4 | Completed | Novartis Pharmaceuticals | 9 | 2008-10-30 | 2017-02-23 |
| Re-treatment of Participants With Paget's Disease Using Zoledronic Acid Zoledronic Acid - Paget's Disease of the Bone | Phase 4 | Completed | Novartis Pharmaceuticals | 6 | 2008-10-21 | 2021-05-26 |
| Sodium Risedronate Tablets - Special Drug Use Surveillance in Patients With Osseous Paget's Disease (All-case Surveillance) -48-week Surveillance - Sodium risedronate - Osseous Paget's Disease | Completed | Takeda | 315 | 2008-08-01 | 2019-06-03 | |
| Impact on Reducing the Incidence of Low Serum Calcium by Providing Educational Materials on the Need to Take Daily Supplemental Calcium and Vitamin D to Patients With Paget's Disease Treated With Reclast® Reclast (ZOL446, zoledronic acid), Calcium, Vitamin D - Paget's Disease of the Bone, Hypocalcemia | Phase 4 | Completed | Novartis Pharmaceuticals | 81 | 2008-05-01 | 2015-03-06 |
| Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study Lapatinib, Trastuzumab, Paclitaxel - Neoplasms, Breast | Phase 3 | Completed | Novartis Pharmaceuticals | 455 | 2008-01-05 | 2021-09-21 |
| Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD) Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia, Paget Disease of Bone | Recruiting | University of California, Irvine | 50 | 2007-11-15 | 2025-06-18 | |
| Genetic Study of Families Affected by Paget's Disease of Bone Paget's Disease of Bone | Completed | Assistance Publique - Hôpitaux de Paris | 83 | 2007-09-01 | 2010-07-13 | |
| Lapatinib and Bevacizumab for Metastatic Breast Cancer lapatinib, bevacizumab - Neoplasms, Breast | Phase 2 | Completed | Novartis Pharmaceuticals | 52 | 2007-02-27 | 2021-10-25 |
| Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18: Osteosarcoma, Paget's Disease | Terminated | State University of New York - Upstate Medical University | 8 | 2002-04-01 | 2013-05-30 | |
| Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period zoledronic acid, placebo to zoledronic acid, Risedronate - Paget's Disease of Bone | Phase 3 | Completed | Novartis Pharmaceuticals | 185 | 2002-04-01 | 2012-06-04 |
| 18F-Fluoride Positron Emission Tomography (PET) in Paget's Disease of Bone Bisphosphonate treatment - Paget's Disease of Bone | Not applicable | Completed | Université Catholique de Louvain | 20 | 2002-02-01 | 2006-03-22 |
| A Research Study to Test the Effectiveness of MK0217 in Patients With Paget's Bone Disease (0217-206)(COMPLETED) alendronate - Paget's Disease of Bone | Phase 3 | Completed | Organon and Co | 60 | 2001-10-01 | 2024-08-14 |
| Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period Zoledronic Acid, Risedronate, Placebo to Risedronate - Paget's Disease of Bone | Phase 3 | Completed | Novartis Pharmaceuticals | 172 | 2001-01-01 | 2012-05-15 |
| Bisphosphonate Therapy for Osteogenesis Imperfecta Alendronate, Pamidronate - Osteogenesis Imperfecta, Osteoporosis | Phase 4 | Completed | Indiana University | 18 | 1999-08-01 | 2017-06-14 |
| Optical Biopsy of Human Skin in Conjunction With Laser Treatment Optical Biopsy imaging - Malignant Melanoma, Merkel Cell Carcinoma | Completed | University of California, Irvine | 113 | 1999-06-01 | 2022-10-20 |
Showing 20 of 21. Sign in to see all of them.
Breast Neoplasms (3) · Carcinoma, Merkel Cell (2) · Carcinoma, Squamous Cell (2) · Melanoma (2) · Osteoporosis (2) · Osteosarcoma (2) · Anus Neoplasms (1) · Bone Neoplasms (1) · Burns (1) · Carcinoma, Basal Cell (1) · Dysplastic Nevus Syndrome (1) · Fractures, Bone (1) · Frontotemporal Dementia (1) · Hemangioma (1)
Bone Diseases (21) · Musculoskeletal Diseases (21) · Neoplasms (7) · Neoplasms by Site (6) · Skin and Connective Tissue Diseases (6) · Skin Diseases (5) · Metabolic Diseases (4) · Neoplasms by Histologic Type (4) · Nutritional and Metabolic Diseases (4) · Breast Diseases (3) · Neoplasms, Connective Tissue (3) · Neoplasms, Connective and Soft Tissue (3) · Sarcoma (3) · Adenocarcinoma (2) · Bone Diseases, Metabolic (2)
Zoledronic Acid (5) · Calcium (3) · Risedronic Acid (3) · Alendronate (2) · Lapatinib (2) · Vitamin D (2) · Bevacizumab (1) · Goserelin (1) · Letrozole (1) · Magnetic Resonance Spectroscopy (1) · Paclitaxel (1) · Pamidronate (1) · Trastuzumab (1) · delta 24-sterol reductase (1) · ribociclib (1)
Novartis Pharmaceuticals (8) · University of California, Irvine (2) · Assistance Publique - Hôpitaux de Paris (1) · Emory University (1) · Indiana University (1) · Johns Hopkins University (1) · Organon and Co (1) · Sheba Medical Center (1) · State University of New York - Upstate Medical University (1) · Takeda (1) · University of Edinburgh (1) · Université Catholique de Louvain (1) · Vanderbilt-Ingram Cancer Center (1)
United States (10) · United Kingdom (5) · Belgium (4) · Canada (4) · Spain (4) · France (3) · Germany (3) · New Zealand (3) · South Africa (3) · Australia (2) · Argentina (1) · Brazil (1) · China (1) · Czechia (1) · Hong Kong (1)
Iris Vered, M.D (1) · Janet L Crane, M.D. (1) · John S Nelson, M.D,Ph.D (1) · Keith Delman, MD (1) · Laetitia Michou, MD PhD (1) · Linda A DiMeglio, MD, MPH (1) · Stuart Ralston (1)
PMID 12921793, PMID 15034582, PMID 16199218, PMID 16317258, PMID 16419137, PMID 16783167, PMID 16984901, PMID 17224685, PMID 17935506, PMID 18260132, PMID 18536953, PMID 19380227, PMID 19828315, PMID 20104022, PMID 20301649, PMID 21412659, PMID 21643886, PMID 21816654, PMID 21892620, PMID 22257673, PMID 22686199, PMID 22785351, PMID 22909335, PMID 23455423, PMID 23715207, PMID 24422139, PMID 25130998, PMID 25582679, PMID 25716352, PMID 25724235, PMID 25851628, PMID 26181252, PMID 27106764, PMID 27312024, PMID 27684533, PMID 28575052, PMID 28692196, PMID 29754758, PMID 29902299, PMID 30097247, PMID 34921525, PMID 34953442, PMID 35610260, PMID 35841038, PMID 39613746
2008 (1), 2016 (1), U01CA142565 (1)