Optical Biopsy of Human Skin in Conjunction With Laser Treatment

NCT00540566 — Completed, 113 participants, University of California, Irvine

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Registry	NCT00540566
Status	Completed
Study type	Observational
Enrollment	113 (Actual)
Sponsor	University of California, Irvine (Other); collaborators: Beckman Laser Institute University of California Irvine
Conditions	Malignant Melanoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma, Atypical Nevi, Congenital Nevi, Seborrheic Keratosis, Paget's Disease, Dermatofibroma, Kaposi's Sarcoma, Port Wine Stain, Hemangioma, Tattoos, Scleroderma, Burns
Interventions	Optical Biopsy imaging (Device)
Dates	start 1999-06-01, primary completion 2008-06-01, completion 2008-07-01, first posted 2007-10-08, last updated 2022-10-20
Locations	1 site in United States

-Summary

This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with the pathologist looking at the piece of tissue through a microscope makes the diagnosis.

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+Detailed description

The Optical measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development. Each measurement requires less than 5 minutes to execute. The measurements will be taken before and after skin treatment.This non-invasive, non-contact technique has great potential as a means to diagnose different skin problems without the need to obtain a piece of tissue from the skin.

+Arms and interventions

Arm	Type	Interventions	Description
Optical Biopsy		Device: Optical Biopsy imaging	Optical Biopsy imaging

Optical Biopsy imaging (Device): Optical Biopsy imaging

+Outcome measures

Primary outcomes

normal skin [12 weeks]

+Eligibility

Sex: All, ages: 18 Years to 75 Years, accepts healthy volunteers

Inclusion Criteria:

* Male or female age > 18 years

Exclusion Criteria:

* current participation in any other investigational drug evaluation
* inability to understand and carry out instructions

+Locations (1)

Facility	City	Country	Status
Beckman Laser Institute, Unversity of California Irvine	Irvine, California	United States

+Investigators

John S Nelson, M.D,Ph.D, Principal investigator, Beckman Laser Institue, University of California Irvine