23 completed, 5 unknown, 3 terminated, 2 withdrawn. 11 Phase 2, 11 Phase 4, 7 Phase 1, 4 Not applicable, 3 Phase 3.
Follow Pamidronate: new trials by email Literature Review of Pamidronate trials Research Report on Pamidronate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer Bone modifying agent - Breast Cancer, Castration-resistant Prostate Cancer | Phase 4 | Active not recruiting | Ottawa Hospital Research Institute | 240 | 2020-10-09 | 2026-07-21 |
| CHronic Nonbacterial Osteomyelitis International Registry Methotrexate, Sulfasalazine, Leflunomide - Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis | Recruiting | Seattle Children's Hospital | 2000 | 2018-08-01 | 2024-07-30 | |
| 4-weekly Versus 12-weekly Administration of Bone-targeted Agents in Patients With Bone Metastases Pamidronate, Denosumab, Zoledronate - Breast Cancer, Prostate Cancer | Phase 4 | Completed | Ottawa Hospital Research Institute | 263 | 2016-08-01 | 2020-12-02 |
| Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome pamidronate disodium - SAPHO Syndrome | Phase 1 | Completed | Peking Union Medical College Hospital | 30 | 2015-10-01 | 2016-10-13 |
| Chronic Non-bacterial Osteomyelitis Treated With Pamidronate Pamidronatdinatrium, Natrium chloride 9mg/ml - Immune System Disease, Musculoskeletal Disease | Phase 2 | Unknown | University of Aarhus | 32 | 2015-10-01 | 2016-11-16 |
| Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation Pamidronate, Calcium and vitamin D - Osteopenia, Osteoporosis | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 63 | 2015-02-01 | 2024-02-20 |
| Combined Treatment With TNF Inhibitor and Pamidronate in AS Patients: Effect on the Radiographic Progression Pamidronate, Placebo (NaCl 0.9%) - Ankylosing Spondylitis | Phase 4 | Unknown | Bnai Zion Medical Center | 30 | 2014-12-01 | 2014-12-10 |
| Evaluate Time Associated With the Preparation & Administration of Denosumab/Pamidronate in Patients With Solid Tumors and Metastatic Bone Disease denosumab, pamidronate - Solid Tumor, Metastatic Bone Disease | Phase 4 | Withdrawn | Amgen | 2014-11-01 | 2015-02-18 | |
| Bisphosphonate Therapy in MONA Spectrum Disorder Pamidronate or Zoledronate - Bone Density, Pain | Completed | Medical University Innsbruck | 3 | 2013-02-01 | 2016-07-06 | |
| Efficiency and Safety Study of Pamidronate in Inflammatory Back Pain Due to Degenerative Disk Disease Pamidronate, Placebo - Intervertebral Disc Degeneration, Modic I Discopathy | Phase 2 | Unknown | University Hospital, Clermont-Ferrand | 48 | 2013-01-01 | 2013-02-27 |
| Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy: a 48-week Trial golimumab, Pamidronate - Spondyloarthropathy | Phase 4 | Completed | Tuen Mun Hospital | 30 | 2012-08-01 | 2015-05-12 |
| The ODYSSEY TRIAL Phase IV Trial Evaluating the Palliative Benefit of Pamidronate or Zoledronic Acid in Breast Cancer Pamidronate, Zoledronic acid, placebo - Breast Cancer | Phase 4 | Completed | Ottawa Hospital Research Institute | 74 | 2012-08-01 | 2017-07-07 |
| Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer Cyclophosphamide, Capecitabine, Methotrexate, Celecoxib, Pamidronate (or Zoledronate) - Chemotherapy, Breast Cancer, Metastatic | Phase 2 | Terminated | HaEmek Medical Center, Israel | 22 | 2010-03-01 | 2015-07-08 |
| The Use of Bisphosphonates in the Treatment of Avascular Necrosis of the Femoral Head Pamidronate Disodium - Femoral Head Avascular Necrosis | Not applicable | Terminated | The Hospital for Sick Children | 20 | 2009-07-01 | 2017-10-13 |
| Effect of Local Pamidronate in Preventing Bone Loss After Total Hip Arthroplasty pamidronate - Arthroplasty, Mineral Density | Phase 1 | Unknown | General and Teaching Hospital Celje | 40 | 2007-11-01 | 2024-04-15 |
| Prevention of Post Operative Bone Loss in Children pamidronate, saline - Osteoporosis, Cerebral Palsy | Not applicable | Completed | University of New Mexico | 24 | 2007-09-01 | 2023-08-22 |
| Study of Pamidronate for the Prevention of Heterotopic Ossification Pamidronate (AREDIA) - Heterotopic Ossification | Not applicable | Withdrawn | University Hospital, Basel, Switzerland | 2005-06-01 | 2015-03-10 | |
| Arsenic Trioxide and Pamidronate in Treating Patients With Advanced Solid Tumors or Multiple Myeloma pamidronate disodium, arsenic trioxide, laboratory biomarker analysis - Refractory Multiple Myeloma, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | National Cancer Institute (NCI) | 24 | 2005-04-01 | 2013-01-07 |
| Samarium Sm 153 Lexidronam Pentasodium Combined With Zoledronic Acid or Pamidronate in Treating Patients With Relapsed or Refractory Multiple Myeloma and Bone Pain Pamidronate, Zoledronic acid, Sm 153 lexidronam - Multiple Myeloma and Plasma Cell Neoplasm, Pain | Phase 1 / Phase 2 | Completed | Mayo Clinic | 39 | 2005-03-21 | 2018-08-14 |
| A Pilot Trial of IV Pamidronate for Low Back Pain Pamidronate - Chronic Low Back Pain | Phase 1 / Phase 2 | Completed | Pappagallo, Marco, M.D. | 44 | 2004-04-01 | 2010-10-13 |
Showing 20 of 35. Sign in to see all of them.
Multiple Myeloma (7) · Breast Neoplasms (6) · Bone Diseases, Metabolic (5) · Neoplasms, Plasma Cell (5) · Osteoporosis (4) · Fractures, Bone (3) · Neoplasm Metastasis (3) · Osteogenesis Imperfecta (3) · Pain (3) · Acquired Hyperostosis Syndrome (2) · Back Pain (2) · Chronic recurrent multifocal osteomyelitis (2) · Low Back Pain (2) · Spondylitis, Ankylosing (2) · Bone Diseases (1)
Ottawa Hospital Research Institute (3) · National Cancer Institute (NCI) (2) · University of Arkansas (2) · Amgen (1) · Bnai Zion Medical Center (1) · City of Hope Medical Center (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · General and Teaching Hospital Celje (1) · HaEmek Medical Center, Israel (1) · Hackensack Meridian Health (1) · Hospital Clinic of Barcelona (1) · Icahn School of Medicine at Mount Sinai (1) · Indiana University (1) · Masonic Cancer Center, University of Minnesota (1) · Mayo Clinic (1)
United States (16) · Canada (4) · Denmark (2) · Israel (2) · Spain (2) · France (1) · Hong Kong (1) · Norway (1) · Puerto Rico (1) · Slovenia (1) · South Africa (1) · Sweden (1) · United Kingdom (1)
Marco Pappagallo, MD (2) · Andrew L. Pecora, MD, FACP (1) · Angela Dispenzieri, M.D. (1) · Athanasios Fassas, M.D. (1) · Bart Barlogie, MD, PhD (1) · Caroline Marie Andreasen, MD (1) · Chen Li, Master (1) · Christian Meier, MD (1) · Elizabeth A Szalay, MD (1) · George Somlo, MD (1) · James Wright, MD (1) · Joan C Marini, M.D. (1) · John Cunningham, MD (1) · Katherine R. Tuttle, MD,FASN,FACP (1) · Kyriakie Sarafoglou, MD (1)
PMID 16224404, PMID 16365178, PMID 17911175, PMID 18669874, PMID 19393473, PMID 20863761, PMID 24716739, PMID 32484386, PMID 34068083
P30CA015083 (1), P30CA033572 (1), U01CA062505 (1), U10CA021115 (1)