8 completed, 1 recruiting. 9 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 8, Recruiting 1 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow OSA: new trials by email Literature Review of OSA trials Research Report on OSA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study That Tests AD109 in Patients Taking GLP-1 Drugs AD109 - OSA | Phase 2 | Completed | Apnimed | 40 | 2024-05-20 | 2025-02-19 |
| Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA Acetazolamide, Placebo - OSA | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 36 | 2024-01-31 | 2024-03-04 |
| Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea Atomoxetine 80 mg plus Oxybutynin 5 mg, Atomoxetine 80 MG, Placebo - OSA | Phase 1 / Phase 2 | Completed | Brigham and Women's Hospital | 27 | 2023-12-01 | 2025-12-17 |
| AD816 Crossover Study Period A, Period B, Period C - OSA, Obstructive Sleep Apnea | Phase 2 | Completed | Apnimed | 25 | 2023-04-28 | 2023-11-15 |
| Effects of Lemborexant as a Treatment for Moderate-to-severe OSA Patients With Low Arousal Threshold Lemborexant 5 MG Oral Tablet [Dayvigo] Day 1, Lemborexant 5 MG Oral Tablet [Dayvigo] Day 2, Placebo Day 1 - OSA | Phase 1 / Phase 2 | Completed | Chulalongkorn University | 10 | 2023-02-01 | 2025-09-17 |
| Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea Acetazolamide, Eszopiclone, Placebo - OSA, Obstructive Sleep Apnea | Phase 2 | Completed | University of California, San Diego | 20 | 2020-12-01 | 2024-05-29 |
| Dimethyl Fumarate for Obstructive Sleep Apnea Dimethyl fumarate, Placebo - Obstructive Sleep Apnea, OSA | Phase 2 | Completed | University of Michigan | 65 | 2015-05-01 | 2017-05-31 |
| PSG Versus Oxim-capnography to Setup Home NIV Full polysomnography, Oximetry-capnography - COPD, OSA | Phase 2 | Completed | Guy's and St Thomas' NHS Foundation Trust | 14 | 2015-01-01 | 2016-07-12 |
| Validation of the AVAPS AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD) Patients AVAPS-AE, Usual care - COPD, OSA | Phase 2 / Phase 3 | Completed | Patrick Murphy | 10 | 2012-05-01 | 2016-08-18 |
Sleep Apnea, Obstructive (5) · Pulmonary Disease, Chronic Obstructive (2) · Sleep Apnea Syndromes (2) · Apnea (1) · Respiratory Insufficiency (1) · Snoring (1)
Respiration Disorders (7) · Respiratory Tract Diseases (7) · Dyssomnias (6) · Nervous System Diseases (6) · Sleep Disorders, Intrinsic (6) · Sleep Wake Disorders (6) · Apnea (5) · Pathological Conditions, Signs and Symptoms (4) · Sleep Apnea Syndromes (4) · Chronic Disease (2) · Disease Attributes (2) · Lung Diseases (2) · Lung Diseases, Obstructive (2) · Pathologic Processes (2) · Signs and Symptoms (2)
Acetazolamide (2) · Atomoxetine Hydrochloride (1) · Dimethyl Fumarate (1) · Eszopiclone (1) · Tablets (1) · Venlafaxine Hydrochloride (1) · lemborexant (1) · oxybutynin (1)
Apnimed (2) · Brigham and Women's Hospital (2) · Chulalongkorn University (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Patrick Murphy (1) · University of California, San Diego (1) · University of Michigan (1)
United States (6) · Thailand (1) · United Kingdom (1)
Dillon Gilbertson (2) · Christopher Schmickl, MD, PhD (1) · Nicholas Hart (1) · Ronald Farkas, MD (1) · Sarocha Vivatvakin, MD (1) · Scott A Sands, PhD (1) · Scott Sands, PhD (1) · Tiffany J. Braley, MD, MS (1)