3 completed, 1 recruiting. 4 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
Follow OSA: new trials by email Literature Review of OSA trials Research Report on OSA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA Acetazolamide, Placebo - OSA | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 36 | 2024-01-31 | 2024-03-04 |
| Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea Atomoxetine 80 mg plus Oxybutynin 5 mg, Atomoxetine 80 MG, Placebo - OSA | Phase 1 / Phase 2 | Completed | Brigham and Women's Hospital | 27 | 2023-12-01 | 2025-12-17 |
| Effects of Lemborexant as a Treatment for Moderate-to-severe OSA Patients With Low Arousal Threshold Lemborexant 5 MG Oral Tablet [Dayvigo] Day 1, Lemborexant 5 MG Oral Tablet [Dayvigo] Day 2, Placebo Day 1 - OSA | Phase 1 / Phase 2 | Completed | Chulalongkorn University | 10 | 2023-02-01 | 2025-09-17 |
| Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease? Supplemental Oxygen, Continuous Positive Airway Pressure Machine, Room Air - OSA, Sleep Apnea | Phase 1 | Completed | University of California, San Diego | 182 | 2021-10-08 | 2026-05-11 |
Sleep Apnea, Obstructive (2) · Alzheimer Disease (1) · Apnea (1) · Sleep Apnea Syndromes (1) · Sleep Wake Disorders (1)
Dyssomnias (2) · Nervous System Diseases (2) · Pathological Conditions, Signs and Symptoms (2) · Respiration Disorders (2) · Respiratory Tract Diseases (2) · Signs and Symptoms (2) · Sleep Disorders, Intrinsic (2) · Apnea (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Dementia (1) · Mental Disorders (1) · Neurocognitive Disorders (1) · Neurodegenerative Diseases (1) · Neurologic Manifestations (1)
Acetazolamide (1) · Atomoxetine Hydrochloride (1) · Oxygen (1) · Tablets (1) · lemborexant (1) · oxybutynin (1)
Brigham and Women's Hospital (2) · Chulalongkorn University (1) · University of California, San Diego (1)
United States (3) · Thailand (1)
Dillon Gilbertson (2) · Sarocha Vivatvakin, MD (1) · Scott A Sands, PhD (1) · Scott Sands, PhD (1)