3 completed, 3 unknown, 2 recruiting, 1 not yet recruiting. 9 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 9 | Completed 3, Unknown 3, Recruiting 2, Not yet recruiting 1 |
Follow Ocular Surface Disease: new trials by email Literature Review of Ocular Surface Disease trials Research Report on Ocular Surface Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Lacrifill Lacrifill, Saline - Dry Eye, Ocular Surface Disease | Phase 4 | Recruiting | Eye Research Associates, LLC | 40 | 2026-09-02 | 2026-09-25 |
| Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic Keratopathy Patients With Tear Deficiency Patients will receive topical Acoltremon 0.003% ophthalmic solution BID in both eyes over an 8 week period., Alternative would be patient exiting the trial and starting on tears or other standard of care. - Ocular Surface Disease, Neurotrophic Keratopathy Stage 1 | Phase 4 | Recruiting | University of South Florida | 50 | 2026-04-06 | 2026-08-12 |
| This is a Single Center, Open-label Prospective Study to Evaluate the Effect of Xiidra® (Lifitegrast Ophthalmic Solution 5.0%) on Tear Film Biomarkers in Dry Eye (Xiidra®) Lifitegrast Ophthalmic Solution 5.0% - Ocular Surface Disease, Dry Eye Syndrome (DES) | Phase 4 | Not yet recruiting | Pittsburgh Research Institute | 36 | 2026-03-01 | 2026-03-24 |
| A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface Dexamethasone, tobramycin, netilimicin - Ocular Surface Disease, Dry Eye Syndromes | Phase 4 | Unknown | Kasr El Aini Hospital | 60 | 2024-01-10 | 2024-05-08 |
| Cool vs Room-temperature Artificial Tears Refresh Plus Preservative-free Lubricant Eye Drops - Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis), Central Retinal Vein Occlusion With Macular Edema | Phase 4 | Completed | University of Iowa | 124 | 2022-03-01 | 2025-03-04 |
| Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy Dextenza 0.4Mg Ophthalmic Insert - Dry Eye Disease, Cataract Surgery | Phase 4 | Unknown | Prism Vision Group | 35 | 2021-01-01 | 2020-12-11 |
| Platelet Rich Plasma Eye Drops for Treatment of Ocular Surface Disease Autologous platelet rich plasma eye drops - Ocular Surface Disease, Dry Eye Syndromes | Phase 4 | Unknown | University Health Network, Toronto | 100 | 2021-01-01 | 2020-10-29 |
| Outcome of Omega 3 FA and Punctal Plugs on Ocular Surface Disease Omega 3, punctal plug - Ocular Surface Disease | Phase 4 | Completed | Benha University | 90 | 2018-07-02 | 2019-11-26 |
| 24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy tafluprost, tafluprost and dorzolamide/timolol - Glaucoma, Ocular Surface Disease | Phase 4 | Completed | Aristotle University Of Thessaloniki | 43 | 2015-03-01 | 2020-12-17 |
Dry Eye Syndromes (5) · Disease (1) · Eye Pain (1) · Glaucoma (1) · Macular Edema (1)
Eye Diseases (7) · Lacrimal Apparatus Diseases (5) · Eye Manifestations (1) · Macular Degeneration (1) · Neurologic Manifestations (1) · Ocular Hypertension (1) · Pain (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Retinal Degeneration (1) · Retinal Diseases (1) · Signs and Symptoms (1)
Calcium Dobesilate (1) · Dexamethasone (1) · Docosahexaenoic Acids (1) · Punctal Plugs (1) · Sodium Chloride (1) · Timolol (1) · Tobramycin (1) · dorzolamide (1) · dorzolamide-timolol combination (1) · lifitegrast (1) · tafluprost (1)
Aristotle University Of Thessaloniki (1) · Benha University (1) · Eye Research Associates, LLC (1) · Kasr El Aini Hospital (1) · Pittsburgh Research Institute (1) · Prism Vision Group (1) · University Health Network, Toronto (1) · University of Iowa (1) · University of South Florida (1)
United States (4) · Canada (1) · Egypt (1) · United Arab Emirates (1)
Anastasios G Konstas, MD, PhD (1) · Cynthia Matossian, MD (1) · Douglas Jin, MD (1) · Leanne T Labriola, DO, MBA (1) · Pedram Hamrah, MD (1)