98 completed, 7 terminated, 5 unknown, 5 withdrawn. 121 Phase 3, 12 Phase 2.
Follow Myelitis: new trials by email Literature Review of Myelitis trials Research Report on Myelitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria | Phase 3 | Not yet recruiting | Tanabe Pharma Corporation | 344 | 2026-10-01 | 2026-08-28 |
| A Study to Evaluate the Mucosal Intestinal Immunity to Poliovirus Type-2 of nOPV2 at Birth Dose in Healthy IPV Vaccinated Infants nOPV2 - Poliomyelitis | Phase 3 | Recruiting | Fidec Corporation | 740 | 2026-04-30 | 2026-09-09 |
| Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX) High-dose corticosteroids (HDCS), High-dose corticosteroids (HDCS) and PLEX - Optic Neuritis, Myelitis | Phase 3 | Recruiting | Mayo Clinic | 382 | 2025-07-11 | 2026-09-24 |
| A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series LBVD, Pentavalent vaccine and Inactivated Polio vaccine - Diphtheria, Tetanus | Phase 2 / Phase 3 | Active not recruiting | LG Chem | 1186 | 2025-05-30 | 2026-09-03 |
| Azathioprine in MOGAD Azathioprine, Placebo - Central Nervous System Inflammation, MOG-IgG Associated Disease | Phase 3 | Recruiting | Hospices Civils de Lyon | 126 | 2023-12-12 | 2025-02-04 |
| A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase â…˘ Clinical Trial of sIPV Vaccine Sabin Strain Inactivated Poliovirus Vaccine - Poliomyelitis, Polio | Phase 3 | Completed | Sinovac Biotech Co., Ltd | 1442 | 2023-05-22 | 2025-12-18 |
| A Study to Evaluate Safety and Immunogenicity of Sequential Vaccination of Sabin Inactivated Poliomyelitis Vaccine (Vero Cell) and Live Attenuated Poliomyelitis Vaccine in Healthy 2-month-old Infants sIPV+bOPV, wIPV+bOPV - Poliomyelitis | Phase 3 | Completed | Beijing Minhai Biotechnology Co., Ltd | 300 | 2023-03-08 | 2024-12-30 |
| Study to Evaluate Eupolio(IPV)'s Safety, Long-term Protective Effect and Boosting Effect of One Booster Dose in the Three Primary Vaccination Plus Boosting Schedule, and Protective Effect in the Schedule With Bivalent OPV in Infants Eupolio - Poliomyelitis, Vaccine Reaction | Phase 3 | Completed | LG Chem | 2001 | 2023-01-10 | 2025-04-06 |
| Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC Vibegron - Neurogenic Detrusor Overactivity | Phase 2 / Phase 3 | Recruiting | Urovant Sciences GmbH | 71 | 2022-10-12 | 2026-06-15 |
| Evaluation of Safety and Immunogenicity of Inactivated Adjuvanted Polio Vaccine in Comparison With Licensed Inactivated Poliovirus Vaccine SII Inactivated Salk Polio Vaccine (Adsorbed) - Lot A, SII Inactivated Salk Polio Vaccine (Adsorbed) - Lot B, SII Inactivated Salk Polio Vaccine (Adsorbed) - Lot C - Poliomyelitis | Phase 3 | Completed | Serum Institute of India Pvt. Ltd. | 1072 | 2022-01-09 | 2023-10-23 |
| Study to Evaluate Safety and Immunogenicity of nOPV2 at Different Intervals in Infants nOPV2 - Poliomyelitis | Phase 3 | Completed | Fidec Corporation | 905 | 2021-12-16 | 2024-08-23 |
| Evaluation of the Immunogenicity and Safety of Concomitant Administration of Novel Oral Polio Type 2 Vaccine and Bivalent Oral Polio Vaccine bOPV and nOPV2 - Poliomyelitis | Phase 3 | Withdrawn | Fidec Corporation | 2020-12-01 | 2022-01-14 | |
| Safety of Sabin Inactivated Poliovirus Vaccine in Adults, Children and Infants and Lot Consistency Immunogenicity, and Safety of the msIPV in 2 Months Old Infants Experimental vaccine, IPV control vaccine, single-person sIPV control vaccine - Poliomyelitis | Phase 3 | Completed | Sinovac Biotech Co., Ltd | 1572 | 2020-11-05 | 2024-04-15 |
| Lot-consistency Clinical Trial of Sabin Strain Inactivated Polio Vaccine Three doses of experimental sIPV of lot 1 at the schedule of 2,3,4 months of age, Three doses of experimental sIPV of lot 2 at the schedule of 2,3,4 months of age, Three doses of experimental sIPV of lot 3 at the schedule of 2,3,4 months of age - Poliomyelitis | Phase 3 | Completed | Sinovac Biotech Co., Ltd | 1300 | 2020-05-11 | 2021-08-18 |
| A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder Eculizumab - Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder | Phase 2 / Phase 3 | Terminated | Alexion Pharmaceuticals, Inc. | 5 | 2020-01-14 | 2024-09-25 |
| To Evaluate the Immunogenicity and Safety of DTaP-IPV Vaccine Administered as a Boosting Dose to Healthy Children of 4-6 Years DTaP-IPV combination vaccine - Diphtheria, Tetanus | Phase 3 | Unknown | Boryung Biopharma Co., Ltd. | 249 | 2019-12-26 | 2020-11-06 |
| An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD Ravulizumab - Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder | Phase 3 | Completed | Alexion Pharmaceuticals, Inc. | 58 | 2019-12-09 | 2025-10-14 |
| Confirmatory Study of BK1310 in Healthy Infants DPT-IPV-Hib, Hib vaccine, DPT-IPV - Tetanus, Diphtheria | Phase 3 | Completed | Tanabe Pharma Corporation | 267 | 2019-04-01 | 2026-01-06 |
| Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series LBVD (Hexavalent vaccine), Pentavalent vaccine and Inactivated Polio vaccine (Sabin strains) - Diphtheria, Tetanus | Phase 2 / Phase 3 | Completed | LG Chem | 60 | 2018-07-18 | 2026-09-03 |
| A Clinical Trial to Evaluate the Immunogenicity and Safety of sIPV in a "2+1"Sequential Schedule With bOPV in Infants sIPV-sIPV-bOPV vaccination schedule, wIPV-wIPV-bOPV vaccination schedule - Poliomyelitis | Phase 3 | Completed | Sinovac Biotech Co., Ltd | 240 | 2018-06-12 | 2019-01-31 |
Showing 20 of 121. Sign in to see all of them.
Poliomyelitis (101) · Diphtheria (64) · Tetanus (62) · Whooping Cough (48) · Haemophilus Infections (40) · Hepatitis B (37) · Myelitis, Transverse (8) · Neuromyelitis Optica (7) · Optic Neuritis (6) · Paraparesis, Tropical Spastic (6) · Postpoliomyelitis Syndrome (6) · Bacterial Infections (4) · Demyelinating Diseases (4) · Recurrence (4) · Virus Diseases (4)
Central Nervous System Diseases (121) · Central Nervous System Infections (121) · Infections (121) · Nervous System Diseases (121) · Neuroinflammatory Diseases (121) · Spinal Cord Diseases (121) · RNA Virus Infections (112) · Virus Diseases (108) · Enterovirus Infections (106) · Neuromuscular Diseases (106) · Picornaviridae Infections (106) · Bacterial Infections and Mycoses (66) · Gram-Positive Bacterial Infections (66) · Actinomycetales Infections (64)
diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (16) · DTaP-IPV-HB-PRP-T vaccine (9) · Poliovirus Vaccine, Inactivated (9) · Diphtheria-Tetanus-acellular Pertussis Vaccines (8) · Heptavalent Pneumococcal Conjugate Vaccine (7) · Pentavac (7) · Tetanus Toxoid (7) · pentacel (6) · Haemophilus influenza type b polysaccharide vaccine-tetanus toxin conjugate (5) · 13-valent pneumococcal vaccine (4) · Hiberix (4) · Immunoglobulins, Intravenous (4) · Hepatitis B Vaccines (3) · HibTITER protein, Haemophilus influenzae (3) · RIX4414 vaccine (3)
Sanofi Pasteur, a Sanofi Company (27) · GlaxoSmithKline (20) · Sanofi (9) · Sinovac Biotech Co., Ltd (6) · Fidec Corporation (5) · Merck Sharp & Dohme LLC (5) · Alexion Pharmaceuticals, Inc. (4) · LG Chem (4) · Centers for Disease Control and Prevention (3) · Institute of Medical Biology, Chinese Academy of Medical Sciences (3) · Statens Serum Institut (3) · Beijing Minhai Biotechnology Co., Ltd (2) · Imperial College London (2) · MCM Vaccines B.V. (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2)
China (19) · United States (13) · Germany (11) · South Korea (11) · Japan (10) · France (7) · Italy (7) · Spain (7) · United Kingdom (7) · Thailand (6) · Bangladesh (5) · Canada (5) · Denmark (5) · Philippines (5) · Poland (5)
Ingrid Kromann (3) · Yuemei Hu (3) · Abhijeet Anand, MBBS, MPH (2) · Zhaojun Mo, Master (2) · Acary Souza Bulle Oliveira, MD, PhD (1) · Anne Fiquet, MD (1) · Brian G. Weinshenker (1) · Byeonguk Eun (1) · Changgui Li, PHD (1)
PMID 26873055, PMID 32273184, PMID 33676197, PMID 34498507, PMID 16984654, PMID 17090650, PMID 19117896, PMID 19952980, PMID 21219984, PMID 21289531, PMID 21334243, PMID 21441781, PMID 21807056, PMID 22001281, PMID 22157567, PMID 22273029, PMID 22349525, PMID 22475857, PMID 22531237, PMID 22691430, PMID 22720101, PMID 23966556, PMID 25765966, PMID 26009577, PMID 27288217, PMID 27510380, PMID 27846055, PMID 27846058, PMID 27879555, PMID 28274276, PMID 28639937, PMID 29576304, PMID 30958543, PMID 31050279, PMID 31703934, PMID 32307307, PMID 32676980, PMID 33284114, PMID 33310418, PMID 33351072, PMID 34803867, PMID 35044877, PMID 37745024, PMID 38109921, PMID 38356884, PMID 38430272, PMID 38582691, PMID 40505670, PMID 41144397, PMID 41782198
2019 (2), 2014 (1), 2018 (1)