18 completed, 3 recruiting, 3 unknown, 2 terminated. 13 Not applicable, 6 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 10, Recruiting 2, Active not recruiting 1 |
| Phase 3 | 6 | Completed 3, Terminated 2, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
Follow Postpoliomyelitis Syndrome: new trials by email Literature Review of Postpoliomyelitis Syndrome trials Research Report on Postpoliomyelitis Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease Whole-body Electrical Muscle Stimulation Exercise - Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | University of Missouri-Columbia | 50 | 2026-03-10 | 2026-03-17 |
| Effectiveness of Transcranial Magnetic Stimulation Treatment in Patients Diagnosed With Postpolio Syndrome Repetitive transcranial magnetic stimulation (rTMS), Sham rTMS, Individualized home exercise program - Postpolio Syndrome | Not applicable | Completed | Ege University | 28 | 2024-10-01 | 2026-09-10 |
| Nomad P-KAFO Study Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH) - Cerebrovascular Accident, Post-polio Syndrome | Not applicable | Recruiting | Shirley Ryan AbilityLab | 36 | 2024-03-01 | 2026-05-11 |
| Evaluation of Fatigue Severity, Mood, and Quality of Life in Post-Polio Syndrome No intervention - Polio and Post-polio Syndrome, Fatigue | Completed | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | 40 | 2023-12-01 | 2024-02-20 | |
| Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease 232 Electrode Electrophysiology (EEG-ECG-EMG-EXG) - Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Motor Neuron Disease Progressive Spinal Muscle Atrophy | Unknown | University of Dublin, Trinity College | 240 | 2023-06-15 | 2024-03-20 | |
| Treatment of Post-poliomyelitis Syndrome by Intravenous Immunoglobulin Post-Poliomyélitis Syndrom | Completed | University Hospital, Montpellier | 17 | 2019-06-28 | 2020-03-10 | |
| A Community Wellness Program for Adults Living With Long-term Physical Disability EnhanceWellness for Disability (EW-D), Wellness Education - Physical Disability | Not applicable | Completed | University of Washington | 516 | 2019-01-31 | 2023-11-21 |
| Safety and Immunogenicity of a Sabin Inactivated Poliovirus Vaccine. Three-dose regimen of high dosage investigational sIPV, Three-dose regimen of medium dosage investigational sIPV, Three-dose regimen of low dosage investigational sIPV - Polio and Post-Polio Syndrome | Phase 2 | Completed | Jiangsu Province Centers for Disease Control and Prevention | 600 | 2017-12-28 | 2019-04-03 |
| Spinal Cord Gray Matter Imaging in Post Polio Syndrome magnetic resonance (MR) Imaging, quantitative muscle force assessment - Post-polio Syndrome | Unknown | University Hospital, Basel, Switzerland | 40 | 2017-05-22 | 2020-06-24 | |
| L-Citrulline in Patients With Post-Polio Syndrome 15g L-citrulline daily p.o., Placebo - Post-Polio Syndrome | Phase 3 | Completed | Dirk Fischer | 30 | 2016-06-14 | 2019-01-23 |
| Whole Body Vibration on Muscle Strength in Patients With Postpolio Syndrome Whole-body Vibration Device - Postpolio Syndrome | Not applicable | Completed | Koç University | 14 | 2015-10-01 | 2020-05-15 |
| Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis 128 electrode electroencephalography (EEG), Bipolar surface electromyography (sEMG), High-density electromyography (HD-EMG) - ALS (Amyotrophic Lateral Sclerosis), Postpoliomyelitis Syndrome | Recruiting | University of Dublin, Trinity College | 400 | 2015-10-01 | 2022-12-23 | |
| Clinical Trial of a Serious Game for Individuals With SCI/D SCI Hard - Spinal Cord Injury, Spinal Cord Involvement | Not applicable | Completed | University of Michigan | 184 | 2015-02-05 | 2019-02-22 |
| Study of the Efficacy and Safety of Immune Globulin Intravenous (Human) Flebogamma® 5% Dual Inactivation and Filtration (DIF) in Participants With Post-polio Syndrome Flebogamma® 5% DIF, Placebo - Post-polio Syndrome | Phase 2 / Phase 3 | Terminated | Instituto Grifols, S.A. | 191 | 2014-09-23 | 2025-12-05 |
| Enhance Wellness for Individuals With Long-Term Physical Disabilities Enhance Wellness - Multiple Sclerosis, Muscular Dystrophy | Not applicable | Completed | University of Washington | 240 | 2014-05-12 | 2018-04-03 |
| Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis C-brace, Stance control orthosis - Spinal Cord Injuries, Poliomyelitis | Not applicable | Active not recruiting | Shirley Ryan AbilityLab | 24 | 2014-02-01 | 2025-05-01 |
| Activity and Fatigue of the Respiratory Muscles and Pulmonary Characteristics in Post-Polio Patients Electronyugraphy - Post-polio Syndrome | Not applicable | Completed | Hadassah Medical Organization | 24 | 2013-01-01 | 2017-02-27 |
| Glutathione and Health With Post-Polio Syndrome Glutathione - Post-polio Syndrome, Physical Activity | Not applicable | Completed | University of Michigan | 20 | 2011-08-01 | 2017-02-17 |
| Arm Cycling to Improve Fitness in Polio Survivors Upper Limb Ergometry - Postpoliomyelitis Syndrome | Not applicable | Completed | Royal College of Surgeons, Ireland | 55 | 2010-07-01 | 2013-09-19 |
| Intravenous Immunoglobulins for Post-Polio Syndrome intravenous immunoglobulins, Saline solution - Post-polio Syndrome | Phase 3 | Completed | Azienda Ospedaliera Universitaria Integrata Verona | 50 | 2008-01-01 | 2012-02-27 |
Showing 20 of 28. Sign in to see all of them.
Poliomyelitis (7) · Spinal Cord Injuries (5) · Amyotrophic Lateral Sclerosis (4) · Multiple Sclerosis (4) · Fatigue (3) · Motor Activity (3) · Motor Neuron Disease (3) · Muscular Dystrophies (3) · Neuromuscular Diseases (3) · Pain (3) · Asthenia (2) · Depression (2) · Muscular Atrophy, Spinal (2) · Arthritis (1)
Central Nervous System Diseases (28) · Central Nervous System Infections (28) · Enterovirus Infections (28) · Infections (28) · Muscular Diseases (28) · Muscular Disorders, Atrophic (28) · Musculoskeletal Diseases (28) · Myelitis (28) · Nervous System Diseases (28) · Neurodegenerative Diseases (28) · Neuroinflammatory Diseases (28) · Picornaviridae Infections (28) · RNA Virus Infections (28) · Virus Diseases (28) · Spinal Cord Diseases (27)
Immunoglobulins, Intravenous (3) · Carnitine (1) · Glutathione (1) · Magnetic Resonance Spectroscopy (1) · Modafinil (1) · Neurofeedback (1) · Piracetam (1) · Saline Solution (1) · Transcranial Magnetic Stimulation (1) · X-Rays (1) · gamma-Globulins (1)
National Institute of Neurological Disorders and Stroke (NINDS) (4) · Shirley Ryan AbilityLab (2) · University of Dublin, Trinity College (2) · University of Michigan (2) · University of Washington (2) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Biolab Sanus Farmaceutica (1) · Calliditas Therapeutics AB (1) · Dirk Fischer (1) · Ege University (1) · Hadassah Medical Organization (1) · Haukeland University Hospital (1) · Instituto Grifols, S.A. (1) · Istanbul Physical Medicine Rehabilitation Training and Research Hospital (1) · Jiangsu Province Centers for Disease Control and Prevention (1)
United States (13) · Ireland (3) · Turkey (Türkiye) (3) · Switzerland (2) · Brazil (1) · Canada (1) · China (1) · Czechia (1) · Denmark (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Netherlands (1) · Poland (1)
Orla Hardiman, BSc MB BCh BAO MD FRCPI FAAN (2) · Acary Souza Bulle Oliveira, MD, PhD (1) · Arzu On, Prof.Dr (1) · Claire Kalpakjian, PhD, MS (1) · Dara Meldrum, MSc (1) · Deirdre E Murray, BSc (1) · Dirk Fischer, Prof. (1) · Elisabeth Farbu, MD, PhD (1) · Frances Horgan, PhD (1) · Ivan Molton, PhD (1) · Ivan R Molton, PhD (1) · Kristian Borg, MD, Prof (1) · Marinos Dalakas, MD (1)
PMID 10025486, PMID 16713921, PMID 17990291, PMID 18816600, PMID 22233167, PMID 23234560, PMID 23903028, PMID 24941350, PMID 25984923, PMID 28274276, PMID 29752819, PMID 31379723, PMID 32162497, PMID 32676980, PMID 32867698, PMID 32976844, PMID 39287519, PMID 39969182, PMID 8148458, PMID 9790485
R01NR016942 (1)