11 recruiting. 11 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Recruiting 11 |
| Phase 3 | 3 | Recruiting 3 |
| Phase 1 | 1 | Recruiting 1 |
Follow Mycoses: new trials by email Literature Review of Mycoses trials Research Report on Mycoses
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biweekly Long-term Occidiofungin Study for Suppression of Mycotic Recurrence OCF001 Intravaginal Gel, Placebo Gel - Candidiasis, Vulvovaginal | Phase 2 | Recruiting | Sano Chemicals Inc | 36 | 2026-06-04 | 2026-06-15 |
| Olorofim in Early Coccidioidal Meningitis olorofim - Coccidioidal Meningitis | Phase 2 | Recruiting | Fariba Donovan | 12 | 2026-06-01 | 2026-07-27 |
| CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia Caspofungin Acetate 50 MG, Physiologic saline - Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection | Phase 1 / Phase 2 | Recruiting | University Hospital, Tours | 100 | 2025-12-02 | 2026-10-09 |
| Platform Trial For Cryptococcal Meningitis (PLATFORM-CM) Standard of care, Oteseconazole - antifungal therapy 1, Turletricin injection - antifungal therapy 2 - Hiv, Cryptococcal Meningitis | Phase 2 / Phase 3 | Recruiting | David Boulware | 2000 | 2025-05-28 | 2026-07-27 |
| Pharmacogenomics for Better Treatment of Fungal Infections Clinical Trial genotype-directed dosing with dosing software based on therapeutic drug monitoring - Fungal Infection, Haematological Malignancy | Phase 2 | Recruiting | The University of Queensland | 104 | 2025-04-14 | 2026-04-16 |
| Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study 1% Tolnaftate Stick Formula A, 1% Tolnaftate Stick Formula B, 1% Tolnaftate Stick Formula C - Tinea Pedis | Phase 2 | Recruiting | Propedix, Inc. | 150 | 2024-12-30 | 2025-11-28 |
| A Study of ATB1651 in Adults With Mild to Moderate Onchomycosis ATB1651-102- Cohort 1, ATB1651-102- Cohort 2, ATB1651-102- Cohort 3 - Onychomycosis | Phase 2 | Recruiting | AmtixBio Co., Ltd. | 120 | 2024-07-01 | 2025-02-19 |
| Efficacy and Safety of Clotrimazole+Lactulose Vaginal Suppositories Vs. Clotrimazole Monotherapy in Adult Women with Candidal Vaginitis/Vulvovaginitis Clotrimazole+Lactulose., Canesten (Clotrimazole), Lactulose - Candidal Vulvovaginitis (ICD-10 Code: B37.3), Vulvovaginal Candidiasis (VVC) | Phase 2 / Phase 3 | Recruiting | AVVA Pharmaceuticals Ltd. | 264 | 2024-02-29 | 2025-02-19 |
| Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults Co-Trimoxazole, Rezafungin Acetate / Co Trimoxazole - Pneumocystis Pneumonia | Phase 2 | Recruiting | Mundipharma Research Limited | 50 | 2023-11-14 | 2025-04-03 |
| Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127) Posaconazole IV 6 mg/kg, Posaconazole PFS 6 mg/kg - Invasive Fungal Infection | Phase 2 | Recruiting | Merck Sharp & Dohme LLC | 40 | 2022-02-22 | 2026-08-12 |
| Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia Single dose liposomal Amphotericin and Fluconazole, Fluconazole - Cryptococcal Meningitis | Phase 2 / Phase 3 | Recruiting | Makerere University | 356 | 2019-06-20 | 2026-04-28 |
Candidiasis, Vulvovaginal (2) · Meningitis, Cryptococcal (2) · Pneumonia, Pneumocystis (2) · Acquired Immunodeficiency Syndrome (1) · Coccidioidal Meningitis (1) · Coccidioidomycosis (1) · Communicable Diseases (1) · Hematologic Neoplasms (1) · Infections (1) · Invasive Fungal Infections (1) · Lung Diseases, Interstitial (1) · Neoplasms (1) · Onychomycosis (1) · Pneumocystis Infections (1)
Bacterial Infections and Mycoses (11) · Infections (10) · Central Nervous System Diseases (3) · Central Nervous System Fungal Infections (3) · Central Nervous System Infections (3) · Genital Diseases (3) · Meningitis (3) · Meningitis, Fungal (3) · Nervous System Diseases (3) · Neuroinflammatory Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Urogenital Diseases (3) · Candidiasis (2) · Cryptococcosis (2)
Amphotericin B (1) · Caspofungin (1) · Clotrimazole (1) · Fluconazole (1) · Lactulose (1) · Rezafungin (1) · Standard of Care (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · liposomal amphotericin B (1) · occidiofungin (1) · olorofim (1) · posaconazole (1)
AVVA Pharmaceuticals Ltd. (1) · AmtixBio Co., Ltd. (1) · David Boulware (1) · Fariba Donovan (1) · Makerere University (1) · Merck Sharp & Dohme LLC (1) · Mundipharma Research Limited (1) · Propedix, Inc. (1) · Sano Chemicals Inc (1) · The University of Queensland (1) · University Hospital, Tours (1)
United States (5) · Russia (2) · Uganda (2) · Australia (1) · Belarus (1) · Belgium (1) · France (1) · Greece (1) · Israel (1) · Mexico (1) · New Zealand (1) · Peru (1) · Poland (1) · South Africa (1) · South Korea (1)
Christina Muzny, MD (1) · David B Meya, MBChB, MMed, PhD (1) · David R Boulware, MD, MPH (1) · Fariba Donovan, MD, PhD (1) · Jason A Roberts, PhD (1) · Mohit Joshi, MD (1)
PMID 41151592, PMID 16304338, PMID 18046534, PMID 20946413, PMID 22548840, PMID 23940606, PMID 26935726, PMID 30776290, PMID 31548210, PMID 31633150, PMID 32194238, PMID 39044381, PMID 9872631
2023 (2), 2019 (1)