46 completed, 8 unknown, 7 not yet recruiting, 7 terminated. 25 Phase 2, 22 Phase 3, 16 Phase 4, 9 Phase 1, 6 Not applicable.
Follow liposomal amphotericin B: new trials by email Literature Review of liposomal amphotericin B trials Research Report on liposomal amphotericin B
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST) Liposomal Amphotericin B (LAmB), Flucytosine (5FC), Flucytosine (5FC) placebo pill - Talaromycosis | Phase 3 | Not yet recruiting | Duke University | 428 | 2026-11-01 | 2026-09-21 |
| Safety and Efficacy of Liposomal Amphotericin B for Patients With Invasive Mold Diseases in Liver Transplant Recipients AmBisome (Amphotericin B) Liposome - Invasive Mold Diseases | Not applicable | Not yet recruiting | Beijing Friendship Hospital | 60 | 2026-08-08 | 2026-07-24 |
| Liposomal Amphotericin B for Invasive Fungal Disease in Solid Organ Transplant Recipients Liposomal Amphotericin B, Alternative Systemic Antifungal Therapy - Invasive Fungal Infection, Solid Organ Transplantation | Not yet recruiting | Sichuan Provincial People's Hospital | 120 | 2026-07-01 | 2026-06-24 | |
| Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy EL219, Active Comparator- IV Antifungal (LAmB or voriconazole) - Invasive Mould Infection | Phase 2 | Recruiting | Elion Therapeutics, Inc. | 60 | 2026-02-13 | 2026-10-05 |
| Low-Dose Liposomal Amphotericin B for Invasive Fungal Infection Prophylaxis in Neutropenic Children Liposomal Amphotericin B (LAmB) - Thalassemia, Hematopoietic Stem Cell Transplantation | Recruiting | Haikou Affiliated Hospital of Central South University Xiangya School of Medicine | 30 | 2026-02-01 | 2026-07-24 | |
| Liposomal Amphotericin B in Invasive Aspergillosis With Hepatic Dysfunction LIposomal amphotericin B (L-AmB) treatment - Aspergillosis Invasive | Not applicable | Not yet recruiting | Southeast University, China | 40 | 2025-12-20 | 2026-01-13 |
| Low-dose Liposomal Amphotericin B for Antifungal Prophylaxis in Prolonged Neutropenia Patients Liposomal Amphotericin B - Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia | Recruiting | Haikou Affiliated Hospital of Central South University Xiangya School of Medicine | 30 | 2025-08-01 | 2026-08-13 | |
| Human Bioequivalence Study of Liposomal Amphotericin B for Injection Test product (Liposomal amphotericin B for injection, Sichuan Huiyu Pharmaceutical Co., Ltd.), Reference product (AmBisome®, Astellas Pharma US Inc.) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 58 | 2025-05-25 | 2026-05-27 |
| Single High-dose of Liposomal Amphotericin B in Combination With B/F/TAF for HIV/AIDS-associated Talaromycosis Amphotericin B, AmBisome - HIV/AIDS-associated Talaromycosis | Not applicable | Not yet recruiting | Shanghai Public Health Clinical Center | 116 | 2025-05-01 | 2025-04-13 |
| Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution Working Amphotericine in liposome (Ambisome®) - Tinea Capitis | Phase 2 / Phase 3 | Active not recruiting | Sohag University | 30 | 2025-04-01 | 2025-05-20 |
| Liposomal Amphotericin B Plus Posaconazole/Isavuconazole for Mucormycosis in Hematologic Malignancies: Efficacy and Safety liposomal amphotericin B (3-5 mg/kg/day) combined with posaconazole/isavuconazole - Mucormycosis in Hematologic Malignancies | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 60 | 2025-03-25 | 2025-09-22 | |
| Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS Single high dose of liposomal amphotericin B, L-AmB standard dose - Disseminated Histoplasma Capsulatum Infection, AIDS and Infections | Phase 3 | Recruiting | Federal University of Health Science of Porto Alegre | 279 | 2025-01-16 | 2026-07-27 |
| Antifungal Drugs in Pulmonary Mucormycosis Combination therapy group, Liposomal Amphotericin B - Pulmonary Mucormycosis | Phase 4 | Not yet recruiting | Bin Cao | 312 | 2025-01-10 | 2025-01-01 |
| Efficacy and Safety of Systematic Therapy and Bronchoscopic Interventional Treatment for Pulmonary Mucormycosis transbronchoscopic interventional debridement - Pulmonary Mucormycosis | Not applicable | Unknown | Beijing Tsinghua Chang Gung Hospital | 30 | 2024-07-30 | 2024-07-11 |
| L-AmB_ Retrospective mUlticenter Study on Mycosis prOphylaxis Liposomal Amphotericin B (LAmB) - Invasive Fungal Infections, Prophylaxis | Enrolling by invitation | Istituto Giannina Gaslini | 120 | 2023-12-12 | 2025-05-04 | |
| Bioequivalence of Amphotericin B Liposome for Injection Amphotericin B liposome for injection, AmBisome - Bioequivalence | Phase 1 | Completed | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 32 | 2023-06-02 | 2023-09-28 |
| A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral Leishmaniasis LXE408, Placebo, AmBisome® - Primary Visceral Leishmaniasis | Phase 2 | Completed | Drugs for Neglected Diseases | 101 | 2022-12-27 | 2026-04-30 |
| Amphotericin Versus Posaconazole for Pulmonary Mucormycosis Posaconazole 600 mg followed by posaconazole 300 mg once daily, Liposomal Amphotericin B - Mucormycosis; Pulmonary (Etiology) | Phase 2 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 82 | 2022-07-01 | 2026-05-22 |
| Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly Miltefosine 50mg, Pentoxifylline 400mg, Liposomal Amphotericin B - Leishmaniasis; Brazilian, Leishmaniasis, Mucocutaneous | Phase 2 / Phase 3 | Unknown | University of Brasilia | 100 | 2022-06-22 | 2023-09-15 |
Showing 20 of 78. Sign in to see all of them.
Leishmaniasis, Visceral (15) · Invasive Fungal Infections (11) · Mycoses (8) · Infections (5) · Leukemia, Myeloid, Acute (5) · Meningitis, Cryptococcal (4) · Neutropenia (4) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Aspergillosis (3) · Febrile Neutropenia (3) · Invasive Pulmonary Aspergillosis (3) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Mucormycosis (3) · Multiple Myeloma (3) · Zygomycosis (3)
Gilead Sciences (8) · Drugs for Neglected Diseases (7) · Banaras Hindu University (5) · Astellas Pharma Inc (3) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. (2) · Duke University (2) · Haikou Affiliated Hospital of Central South University Xiangya School of Medicine (2) · Hospital Universitário Professor Edgard Santos (2) · University of Brasilia (2) · Assistance Publique - Hôpitaux de Paris (1) · Aurobindo Pharma Ltd (1) · Bayside Health (1) · Beijing Friendship Hospital (1) · Beijing Tsinghua Chang Gung Hospital (1)
United States (14) · India (12) · France (10) · China (9) · Italy (7) · Spain (7) · Brazil (6) · Germany (6) · Belgium (5) · Canada (5) · United Kingdom (4) · Ethiopia (3) · Netherlands (3) · South Korea (3) · Sudan (3)
Shyam Sundar, MD (5) · Lamine Mahi, MD (2) · Ana LT Rabello, MD PhD (1) · Andrea L de Carvalho, MD (1) · Andreas Groll, M.D. (1) · Anthony P Schwarer, MB, BS, FRACP, MD, FRCPA (1) · Asuncion Moreno, MD (1) · Ban H Tan, Dr (1) · Bill McGhee, PharmD (1) · Bin Cao (1) · Brad Spellberg, MD (1) · C. Orla Morrissey, MB, BCh, FRACP (1) · C.H. Poynton, MD (1) · Carlos Cervera, MD (1)
PMID 26768369, PMID 15459300, PMID 18781879, PMID 19144094, PMID 19804626, PMID 20147716, PMID 21129762, PMID 21147825, PMID 21255828, PMID 21375777, PMID 21397541, PMID 21718522, PMID 21937481, PMID 24454970, PMID 25233346, PMID 25520332, PMID 26048961, PMID 26316385, PMID 26573827, PMID 27627654, PMID 28531175, PMID 28558062, PMID 28662034, PMID 30653490, PMID 30789910, PMID 34764182, PMID 36780493, PMID 37232940, PMID 37988402, PMID 38387646, PMID 39007942, PMID 39044381, PMID 40830172, PMID 41263912, PMID 41513548, PMID 42446237
2008 (1), 2017 (1)