247 completed, 33 unknown, 22 terminated, 20 recruiting. 73 Phase 3, 71 Not applicable, 54 Phase 2, 35 Phase 4, 28 Phase 1.
Follow Candidiasis: new trials by email Literature Review of Candidiasis trials Research Report on Candidiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shortening Treatment Duration in Uncomplicated Candidemia: the CanTEN Trial Caspofungin only within the study, Caspofungin for 3 days within the study, Placebo only within the study - Candidemia, Invasive Candidiasis | Phase 4 | Not yet recruiting | Oliver Cornely, MD | 420 | 2026-09-01 | 2026-09-01 |
| Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment Blue LED Photobiomodulation - Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis | Not applicable | Not yet recruiting | Patricia Lordelo | 150 | 2026-07-30 | 2026-07-13 |
| Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model Pharmacist-Led Prescribing Optimization and Patient Counselling - Oral Lichen Planus, Recurrent Aphthous Stomatitis | Not applicable | Not yet recruiting | University of Fujairah | 336 | 2026-07-01 | 2026-07-22 |
| Biweekly Long-term Occidiofungin Study for Suppression of Mycotic Recurrence OCF001 Intravaginal Gel, Placebo Gel - Candidiasis, Vulvovaginal | Phase 2 | Recruiting | Sano Chemicals Inc | 36 | 2026-06-04 | 2026-06-15 |
| Large Algorithm Setting and Validation Study Nanopath Vaginitis Assay, BD Max™ Vaginal Panel, Cepheid Xpert® Xpress MVP - Bacterial Infections, Bacterial Infections and Mycoses | Recruiting | Nanopath, Inc | 1000 | 2026-06-03 | 2026-07-20 | |
| Evaluation of the Efficacy of a Probiotic Product as an Adjuvant Treatment for Vulvovaginal Candidiasis Bioithas WOMAN® - Vulvovaginal Candidiasis (VVC) | Not applicable | Recruiting | Bioithas SL | 60 | 2026-05-25 | 2026-05-22 |
| Prospective Clinical Study, Using a Medical Device (RepHegyn) as an Adjuvant in the Treatment of Fungal (Candidiasis) and Bacterial Infections Bacterial Infections, Treatment of Fungal Infections, Candidiasis | Not yet recruiting | Innate srl | 34 | 2026-05-01 | 2026-04-14 | |
| The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study Vaginal lactoferrin, Usual care - Bacterial Vaginosis, Candida Vaginal | Not applicable | Recruiting | Guy's and St Thomas' NHS Foundation Trust | 114 | 2026-04-16 | 2026-05-29 |
| An Investigation to Evaluate the Clinical Performance and Safety of pHyph in Adult Women With Vulvovaginal Candidiasis Compared With an Untreated Control Group pHyph - Vulvovaginal Candidiasis (VVC) | Not applicable | Active not recruiting | Gedea Biotech AB | 48 | 2026-03-03 | 2026-05-14 |
| Biofilm Formation and Antifungal Resistance in Candida Species Candida Infection | Not yet recruiting | Assiut University | 300 | 2025-12-20 | 2025-11-24 | |
| Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant Outcomes Non-interventional study - Vulvovaginitis, Candidal, Vulvovaginal Candidiasis | Recruiting | GlaxoSmithKline | 100 | 2025-11-12 | 2026-09-23 | |
| Multi-Gyn FemiTotal for the Treatment and Prevention of Vulvovaginal Candidiasis Symptoms and Bacterial Vaginosis Multi-Gyn FemiTotal - Bacterial Vaginosis, Vaginal Candidiasis | Not applicable | Recruiting | Karo Pharma AB | 80 | 2025-10-22 | 2026-10-02 |
| Oteseconazole in the Treatment of Adults With Vulvovaginal Candidiasis（VVC） Oteseconazole (VT-1161) 150mg capsule - Vulvovaginal Candidiasis | Not yet recruiting | Beijing Tsinghua Chang Gung Hospital | 3000 | 2025-08-10 | 2025-07-01 | |
| Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis Boric acid, Placebo - Vulvovaginal Candidiases, Vulvovaginal Candidiasis, Genital | Phase 3 | Completed | pH-D Feminine Health LLC | 333 | 2025-08-08 | 2026-10-23 |
| A Randomized Study of a Short Duration Therapy for Candidemia Standard of Care (SOC), Shortened duration of antifungal therapy - CANDIDEMIA | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 362 | 2025-07-01 | 2025-03-05 |
| One-stage Exchange in Candida Periprosthetic Infection a Suitable Way to go Candida Infection | Recruiting | University Hospital, Strasbourg, France | 16 | 2025-05-28 | 2025-12-24 | |
| Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC) vaginal cooling device - Vulvovaginal Candidiasis (VVC), Yeast Vaginitis | Not applicable | Recruiting | Coologics, Inc | 55 | 2025-05-22 | 2026-01-30 |
| A Study Comparing Short-course Antifungal Therapy (SCAT) 7 Day vs Standard 14 Day Antifungal Therapy for Uncomplicated Candidemia Antifungal treatment - Candidemia | Not yet recruiting | Augusta University | 150 | 2025-05-01 | 2025-04-04 | |
| Efficacy of the Vacucis Candida® Autovaccine Vacucis autovaccine, Placebo - Oral Candidiasis, Oral Candidiasis Recurrent | Not applicable | Not yet recruiting | University of Santiago de Compostela | 46 | 2025-04-30 | 2024-10-17 |
| Performance Study of the Cobas® BV/CV Test on Samples From Participants With and Without Symptoms of Bacterial Vaginosis and Candida Vaginitis cobas® BV/CV test, BD Max™ Vaginal Panel, Cepheid Xpert Xpress MVP - Bacterial Vaginosis, Candida Vaginitis | Completed | Hoffmann-La Roche | 738 | 2024-12-30 | 2026-10-16 |
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Candidiasis, Vulvovaginal (107) · Candidemia (68) · Candidiasis, Invasive (64) · Candidiasis, Oral (48) · Mycoses (43) · Torulopsis (32) · HIV Infections (29) · Vaginosis, Bacterial (29) · Aspergillosis (25) · Acquired Immunodeficiency Syndrome (18) · Invasive Fungal Infections (16) · Vaginitis (16) · AIDS-Related Opportunistic Infections (12) · AIDS-Related Complex (11)
Bacterial Infections and Mycoses (344) · Infections (340) · Mycoses (302) · Urogenital Diseases (149) · Genital Diseases (147) · Female Urogenital Diseases and Pregnancy Complications (122) · Female Urogenital Diseases (118) · Genital Diseases, Female (116) · Vaginal Diseases (112) · Vulvar Diseases (108) · Vulvitis (108) · Pathological Conditions, Signs and Symptoms (103) · Vulvovaginitis (101) · Invasive Fungal Infections (100)
Fluconazole (58) · Micafungin (25) · Caspofungin (23) · Anidulafungin (16) · Voriconazole (13) · Clotrimazole (12) · ibrexafungerp (11) · Amphotericin B (7) · Miconazole (6) · Nystatin (6) · VT-1161 (6) · Clindamycin (5) · Injections (5) · Itraconazole (5) · posaconazole (5)
Pfizer (26) · Merck Sharp & Dohme LLC (14) · National Institute of Allergy and Infectious Diseases (NIAID) (14) · Scynexis, Inc. (11) · Astellas Pharma Inc (9) · National Cancer Institute (NCI) (9) · Radboud University Medical Center (5) · Bristol-Myers Squibb (4) · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (4) · Gedea Biotech AB (4) · University Hospital, Lille (4) · Basilea Pharmaceutica (3) · Bayer (3) · Central Hospital, Nancy, France (3) · Matinas BioPharma Nanotechnologies, Inc. (3)
United States (129) · France (35) · Spain (23) · Italy (22) · Brazil (19) · Germany (19) · Canada (18) · Netherlands (17) · Belgium (16) · China (16) · Austria (13) · India (12) · South Africa (11) · Turkey (Türkiye) (11) · Greece (9)
David Angulo, MD (6) · Shangrong Fan, M.D. (3) · Alena Jandourek, MD (2) · Marc Engelhardt (2) · Michail S Lionakis, M.D. (2) · Peter Pappas, MD (2) · Raphael F de Souza, DDS, PhD (2) · Robert Krause, MD (2)
PMID 28459966, PMID 28597967, PMID 33891293, PMID 31280481, PMID 36396498, PMID 21147825, PMID 23315320, PMID 23959319, PMID 33438477, PMID 36255448, PMID 38008099, PMID 38319878, PMID 38502709, PMID 39468640, PMID 39529079, PMID 40970688, PMID 41940006, PMID 10747150, PMID 10782340, PMID 11687311, PMID 16127033, PMID 16161031, PMID 16436724, PMID 16648432, PMID 17128343, PMID 17568028, PMID 17719934, PMID 18473572, PMID 18696746, PMID 18813103, PMID 19144094, PMID 19485785, PMID 19804626, PMID 19915602, PMID 20876174, PMID 21961941, PMID 22018278, PMID 22026929, PMID 22144537, PMID 22424952, PMID 22490643, PMID 22504098, PMID 22879929, PMID 22955439, PMID 23543609, PMID 23676114, PMID 23710653, PMID 23726546, PMID 24165173, PMID 24261608
2009 (6), 2008 (3), 2017 (3), 2014 (2), 2015 (1), 2018 (1), 2023 (1), M01RR000030 (1), M01RR000032 (1), M01RR000039 (1), M01RR000044 (1), M01RR000054 (1), M01RR000059 (1), M01RR000070 (1), M01RR000080 (1)