95 completed, 25 unknown, 5 recruiting, 3 not yet recruiting. 39 Phase 2, 36 Not applicable, 21 Phase 3, 17 Phase 1, 16 Phase 4.
Follow Onychomycosis: new trials by email Literature Review of Onychomycosis trials Research Report on Onychomycosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Systemic Antifungal Plus Q-Switched Nd:YAG Laser for Onychomycosis Terbinafine, Q-switched Nd:YAG laser - Onychomycosis | Not applicable | Not yet recruiting | Assiut University | 97 | 2026-10-10 | 2026-10-09 |
| URGO MICKAEL Filmogel, Topical Treatment of Onychomycosis URGO MICKAEL Filmogel - Onychomycosis of Toenail | Not applicable | Recruiting | CEN Biotech | 54 | 2026-01-28 | 2026-09-22 |
| Fractional CO₂ Laser or 40% Urea With Topical Fluconazole Microemulsion in Onychomycosis "Fractional CO2 laser" and "topical fluconazole microemulsion", "Urea 40%" and "topical fluconazole microemulsion" - Onychomycosis | Not applicable | Not yet recruiting | Assiut University | 40 | 2025-06-01 | 2025-06-29 |
| Study in Patients With Onychomycosis Treated With Mycoclear® and Ciclopirox Onychomycosis of Toenails | Not yet recruiting | University of Bologna | 80 | 2025-05-30 | 2025-05-20 | |
| Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis Trichostatin A - Onychomycosis of Toenail | Phase 2 | Active not recruiting | Vanda Pharmaceuticals | 50 | 2025-05-05 | 2026-02-04 |
| Exploring Different Dose-frequency Home Photodynamic Therapy Protocols Using a Novel Home-targeted LED Device for Onychomycosis Photodynamic Therapy with Conventional Methylene Blue, urea 40% cream - Onychomycosis of Toenails, Onychomycosis of Fingernail | Not applicable | Active not recruiting | Chulalongkorn University | 50 | 2025-01-13 | 2026-05-12 |
| Evaluation of a Combination of Two Medical Devices and One Device Use in the Treatment of Toenail Onychomycosis Sérum PURIFIANT, Sérum PURIFIANT in association Sérum BOOSTER - Onychomycosis | Not applicable | Completed | Swiss Footcare Laboratories - Poderm Professional | 44 | 2024-11-12 | 2026-06-24 |
| CLINICAL INVESTIGATION FOR THE EVALUATION OF EFFICACY AND SAFETY OF TWO PRODUCTS FOR THE TREATMENT OF ONYCHOMYCOSIS Enriched, Loceryl 5% - Onychomycosis | Not applicable | Recruiting | Oystershell NV | 88 | 2024-10-30 | 2025-09-03 |
| Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis ISOtretinoin 10 MG, excimer light, Itraconazole 200 mg - Onychomycosis | Phase 1 | Recruiting | Zagazig University | 36 | 2024-07-12 | 2026-04-23 |
| A Study of ATB1651 in Adults With Mild to Moderate Onchomycosis ATB1651-102- Cohort 1, ATB1651-102- Cohort 2, ATB1651-102- Cohort 3 - Onychomycosis | Phase 2 | Recruiting | AmtixBio Co., Ltd. | 120 | 2024-07-01 | 2025-02-19 |
| Clinical Investigation for the Evaluation of Efficacy and Safety of Two Medical Devices for Onychomycosis Treatment Forte, Active Cover Light, Loceryl - Onychomycosis | Not applicable | Unknown | Oystershell NV | 132 | 2024-03-01 | 2024-02-12 |
| A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onychomycosis DBI-001, DBI-002, Aqueous Gel - Onychomycosis | Phase 2 | Suspended | DermBiont, Inc. | 60 | 2023-11-01 | 2023-09-07 |
| Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis Nail Genesis DLSO Product, Nail Genesis DLSO Product (vehicle only) - Distal Lateral Subungual Onychomycosis, Onychomycosis | Not applicable | Unknown | Nail Genesis LLC | 338 | 2023-10-01 | 2023-12-08 |
| Diode Laser and Photodynamic Therapy Vs. Ciclopirox. Diode laser combined with photodynamic-red laser therapy by RapidoPodia Laser Diodo®, Ciclopirox Hydroxypropyl Chitosan (HPCH) Nail Lacquer - Onychomycosis | Phase 4 | Unknown | Universidad Complutense de Madrid | 26 | 2023-09-01 | 2023-05-10 |
| Pilot Study of Swift Microwave Device for Onychomycosis Swift Microwave treatment - weekly x 4wks, Swift Microwave treatment - Every other week x 4wks, Swift Microwave treatment - Every other week x 24wks - Onychomycosis of Toenail | Phase 1 / Phase 2 | Completed | Mediprobe Research Inc. | 39 | 2023-03-27 | 2024-11-18 |
| Infrared Bioeffect System for the Treatment of Onychomycosis infrared thermotherapy instrument - Hyperthermia | Not applicable | Unknown | Gao Xinghua | 60 | 2023-02-24 | 2023-09-14 |
| Effectiveness and Safety of Nailner Brush 2in1 in Onychomycosis topical treatment - Onychomycosis | Not applicable | Completed | Karo Pharma AB | 50 | 2022-07-28 | 2023-10-04 |
| Mycosis Culture Collection From Dermatological Isolated Terbinafine Topical Gel, Itraconazole 200 mg, Terbinafine 250 mg - Onychomycosis, Resistant Infection | Unknown | University of Rome Tor Vergata | 200 | 2022-07-20 | 2024-05-08 | |
| Radiofrequency in Onychomycosis Non ablative radiofrequency - Onychomycosis | Not applicable | Unknown | Cairo University | 20 | 2022-07-01 | 2022-05-25 |
| Lasers in Onychomycosis Laser - Onychomycosis | Not applicable | Unknown | Cairo University | 40 | 2022-06-25 | 2022-06-13 |
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Foot Dermatoses (8) · Mycoses (6) · Keratoderma, Palmoplantar, Epidermolytic (3) · Nails, Malformed (3) · Onycholysis (3) · Diabetes Mellitus, Type 2 (2) · Nail Diseases (2) · Tinea Pedis (2) · Twenty-Nail Dystrophy (2) · Yellow Nail Syndrome (2) · Acne Vulgaris (1) · Cellulitis (1) · Dermatomycoses (1) · Diabetes Mellitus (1)
Bacterial Infections and Mycoses (134) · Skin Diseases (134) · Skin Diseases, Infectious (134) · Skin and Connective Tissue Diseases (134) · Dermatomycoses (133) · Infections (133) · Tinea (133) · Nail Diseases (132) · Mycoses (128) · Foot Diseases (10) · Pathological Conditions, Signs and Symptoms (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Keratoderma, Palmoplantar (3) · Keratoderma, Palmoplantar, Diffuse (3)
Terbinafine (18) · amorolfine (9) · tavaborole (7) · Itraconazole (6) · Solutions (5) · Lasers (4) · efinaconazole (4) · Ciclopirox (3) · Urea (3) · Antifungal Agents (2) · Keratolytic Agents (2) · Tablets (2) · albaconazole (2) · posaconazole (2) · Amphotericin B (1)
Pfizer (11) · Erchonia Corporation (4) · Galderma R&D (4) · Mahidol University (4) · Moberg Pharma AB (4) · Stiefel, a GSK Company (4) · Dow Pharmaceutical Sciences (3) · Oystershell NV (3) · AmtixBio Co., Ltd. (2) · Assiut University (2) · Cairo University (2) · Celtic Pharma Development Services (2) · Chulalongkorn University (2) · Hallux, Inc. (2) · Meiji Seika Pharma Co., Ltd. (2)
United States (67) · Canada (14) · Germany (8) · France (6) · Iceland (6) · Thailand (6) · Mexico (4) · Poland (4) · Belgium (3) · Brazil (3) · Czechia (3) · Dominican Republic (3) · Italy (3) · Spain (3) · Egypt (2)
Eduardo Tschen, MD (2) · Joanne Fraser, PhD (2) · Kent Allenby, MD (2) · Kerry Zang, DPM (2) · Maurizio Caserini, MD (2) · Phoebe Rich, MD (2) · Steven Herrmann, MD (2) · Aditya Gupta, MD,PhD (1)
PMID 25007364, PMID 10233295, PMID 10642676, PMID 14723731, PMID 20347657, PMID 21820203, PMID 21967490, PMID 22236569, PMID 22453588, PMID 22976905, PMID 23278851, PMID 23377392, PMID 23416171, PMID 23884486, PMID 24079583, PMID 24173203, PMID 25013957, PMID 25357174, PMID 25639524, PMID 25872590, PMID 26471716, PMID 27799043, PMID 27815659, PMID 28670355, PMID 30811142, PMID 32421854, PMID 39158295, PMID 39624747, PMID 41024682
2015 (2), 2008 (1)