22 completed, 5 unknown, 2 terminated, 1 active not recruiting. 12 Phase 3, 9 Phase 2, 7 Phase 1, 7 Phase 4, 6 Not applicable.
Follow Clotrimazole: new trials by email Literature Review of Clotrimazole trials Research Report on Clotrimazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone - Bacterial Vaginosis, Vaginal Dysbiosis | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 1794 | 2026-10-01 | 2026-08-27 |
| Comparative Efficacy of Topical Clotrimazole Versus 2% Salicylic Acid in Otomycosis clotrimazole, 2% Salicylic Acid - Otomycosis | Not applicable | Completed | Mayo Hospital Lahore | 60 | 2024-11-20 | 2026-04-17 |
| Efficacy and Safety of Clotrimazole+Lactulose Vaginal Suppositories Vs. Clotrimazole Monotherapy in Adult Women with Candidal Vaginitis/Vulvovaginitis Clotrimazole+Lactulose., Canesten (Clotrimazole), Lactulose - Candidal Vulvovaginitis (ICD-10 Code: B37.3), Vulvovaginal Candidiasis (VVC) | Phase 2 / Phase 3 | Recruiting | AVVA Pharmaceuticals Ltd. | 264 | 2024-02-29 | 2025-02-19 |
| Vertebral Bone Marrow Clot for Spinal Surgery Vertebral bone marrow (vBMA) clot, Bone allograft chips - Degenerative Spine Diseases | Not applicable | Active not recruiting | Istituto Ortopedico Rizzoli | 96 | 2023-05-19 | 2026-05-27 |
| A Protocol for the Role of Fractional CO2 Laser in Consolidation Treatment of Recurrent Vulvovaginal Candidiasis the fractional CO2 laser, Clotrimazole - Vulvovaginal Candidiasis, Genital, Laser Therapy | Not applicable | Unknown | Second Affiliated Hospital of Wenzhou Medical University | 205 | 2019-12-13 | 2020-03-11 |
| Effectiveness Study of Ketoconazole and Betamethasone to Treat Fungal Infection and Dermatophytosis Candicort®, Nizoral®, Baycuten N® - Tinea | Phase 3 | Completed | Ache Laboratorios Farmaceuticos S.A. | 125 | 2019-06-11 | 2021-09-20 |
| Study on the Safety of the Approved Product Empedic L Cream During Its Routine Use (Active Ingredient is Clotrimazole 1%) Clotrimazole 1% (Empecid L Cream, BAYB5097) - Vaginal Candida | Completed | Bayer | 1033 | 2018-07-10 | 2022-07-22 | |
| Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories. Cumin seed extract, clotrimazole - Infection, Fungal | Phase 2 / Phase 3 | Completed | Assiut University | 100 | 2018-03-01 | 2020-06-09 |
| Patients With Vulvovaginal Candidiasis EPP-AF Gel 1%, EPP-AF Gel 2%, Clotrimazole - Vulvovaginal Candidiasis | Phase 1 / Phase 2 | Unknown | University of Sao Paulo | 90 | 2018-01-30 | 2018-10-19 |
| Effects of Antimicrobials on the Altered Skin Flora in Arsenical Keratosis Tetracycline, Clotrimazole, Tetracycline and Clotrimazole - Keratotic Nodular Size | Phase 2 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 30 | 2018-01-21 | 2018-08-17 |
| ProF-001_Phase IIa Candiplus, Clotrimazole - Vulvovaginal Candidiasis (VVC) | Phase 2 / Phase 3 | Completed | ProFem GmbH | 84 | 2017-04-04 | 2019-03-14 |
| Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Boric acid and probiotics, Antibiotic (Clindamycin), Antifungal (Clotrimazole) - Candidiasis, Vaginosis, Bacterial | Phase 4 | Completed | Laboratorios Ordesa | 48 | 2016-07-12 | 2019-11-19 |
| Effect of Concomitant Use of an Antimycotic, an Antibiotic, a Spermicide or Tampons on Pharmacokinetics of Anastrozole and Levonorgestrel Released From Intra-vaginal Ring Anastrozole / Levonorgestrel (BAY98-7196), Gyno-Daktarin, Sobelin vaginal creme - Endometriosis | Phase 1 | Completed | Bayer | 52 | 2015-09-15 | 2017-07-24 |
| To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%) Dapivirine Ring-004, Dapivirine Ring-004 for 28 days along with clotrimazole, Clotrimazole - HIV- Prevention | Phase 1 | Completed | International Partnership for Microbicides, Inc. | 36 | 2015-09-01 | 2017-08-30 |
| Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis Clotrimazole vaginal tablet, Fluconazole - Candidiasis, Vulvovaginal | Phase 4 | Completed | Peking University Shenzhen Hospital | 240 | 2014-07-01 | 2017-05-02 |
| Efficacy and Safety of the Association of Clotrimazole and Metronidazole in the Treatment of Vaginal Discharge From Different Etiologies. Clotrimazole + Metronidazole, Metronidazole, Clotrimazole - Sexual Active Women, Vaginal Discharge | Phase 3 | Withdrawn | Ache Laboratorios Farmaceuticos S.A. | 2013-09-01 | 2016-03-18 | |
| Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis Clotrimazole - Candidiasis, Vulvovaginal | Phase 4 | Completed | Instituto Palacios | 56 | 2013-06-01 | 2015-03-25 |
| Clinical Study to Assess the Efficacy and Safety of G238 Compared to Clotrimazole Otic Solution in the Treatment of Otomycosis G238, Clotrimazole - Otomycosis | Phase 3 | Completed | Salvat | 190 | 2013-05-01 | 2017-04-04 |
| Evaluate the Efficacy and Safety of Tolnaftate Cream in the Treatment of Patients With Fungal Infections Clotrimazole - Fungal Infections, Tinea Pedis | Phase 3 | Unknown | Laboratório Teuto Brasileiro S/A | 90 | 2012-04-01 | 2012-04-12 |
| Effectiveness of 3% Boric Acid in 70% Alcohol Versus 1% Clotrimazole Solution in Otomycosis Patients clotrimazole, 3% Boric acid - Otomycosis | Not applicable | Completed | Khon Kaen Hospital | 120 | 2012-03-01 | 2015-04-28 |
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Candidiasis, Vulvovaginal (8) · Candidiasis (4) · Mycoses (4) · HIV Infections (3) · Otomycosis (3) · Vaginosis, Bacterial (3) · Acquired Immunodeficiency Syndrome (2) · Anemia, Sickle Cell (2) · Genetic Diseases, Inborn (2) · Hematologic Diseases (2) · Rare Diseases (2) · Tinea (2) · Tinea Pedis (2) · AIDS-Related Complex (1) · AIDS-Related Opportunistic Infections (1)
Bayer (3) · Ache Laboratorios Farmaceuticos S.A. (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · AVVA Pharmaceuticals Ltd. (1) · Assistance Publique Hopitaux De Marseille (1) · Assiut University (1) · Azidus Brasil (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Boston Children's Hospital (1) · Dr Bharti Daswani (1) · Instituto Palacios (1) · International Partnership for Microbicides, Inc. (1) · Istituto Ortopedico Rizzoli (1) · Khon Kaen Hospital (1) · Laboratorios Ordesa (1)
United States (9) · Brazil (4) · Spain (3) · China (2) · Germany (2) · Russia (2) · Austria (1) · Bangladesh (1) · Belarus (1) · Canada (1) · Egypt (1) · Hong Kong (1) · India (1) · Italy (1) · Japan (1)
A. D'jamali, MD, MS (1) · Alexandre Frederico, médico (1) · Amalia Reyes-Herrera, M.D. (1) · Asiya Ferdous, MBBS (1) · Bertha Torres-Alvarez, M.D. (1) · Bharti R Daswani, MD, PhD (1) · Bozzettee S (1) · Carlo Brugnara (1) · Chun Wah M. Yuen (1) · Eduardo A. Junior, MD (1) · Eugene Paul Orringer (1) · Herbert Kiss, Ao.Univ.Prof.Dr. (1)
PMID 27073145, PMID 28639702, PMID 32139727, PMID 34033120, PMID 35118056, PMID 40417680
2008 (1), 2014 (1), 2023 (1)