174 completed, 24 unknown, 18 terminated, 10 recruiting. 240 Phase 3, 31 Phase 2.
Follow Mycoses: new trials by email Literature Review of Mycoses trials Research Report on Mycoses
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Echinocandin Added to Standard Treatment for Severe Pneumocystis Pneumonia Echinocandins, Placebo (0.9% Sodium chloride) infusion - Pneumocystis Jirovecii Pneumonia | Phase 3 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2027-04-01 | 2026-10-28 |
| Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers Immediate ART Initiation, Delayed ART Initiation, 10-Week Fluconazole - Cryptococcal Antigenemia, HIV-1-infection | Phase 3 | Not yet recruiting | University of Minnesota | 505 | 2027-01-05 | 2026-09-03 |
| Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT) LAmB B, Posaconazole, World Health Organization (WHO)-recommended SOC - Histoplasmosis | Phase 3 | Not yet recruiting | University of Minnesota | 664 | 2026-11-01 | 2026-10-02 |
| A Study of Itraconazole and Posaconazole for Chronic Pulmonary Aspergillosis Posaconazole Delayed Release Oral Tablet, Itraconazole (ITZ) - Chronic Pulmonary Aspergillosis | Phase 3 | Not yet recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 220 | 2026-11-01 | 2026-10-01 |
| Study to Assess Efficacy, Safety and Tolerability of a Nail Patch in Patients With Nail Fragility, Mychosis, Psoriasis Cosmetic patch containing urea applicated daily for 3 months, Placebo patch application - Nail Psoriasis, Nail Damage | Phase 3 | Recruiting | Wooshin Labottach Co., Ltd. | 72 | 2026-02-01 | 2026-01-26 |
| Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia trimethoprim-sulfamethoxazole - Pneumocystis, Pneumocystis Pneumonia | Phase 3 | Recruiting | Todd C. Lee MD MPH FIDSA | 416 | 2025-11-28 | 2026-02-20 |
| Rezafungin Prophylaxis in Liver Transplant Rezafungin, Standard of care antifungal prophylaxis - Liver Transplant Infection, Fungal Infection | Phase 3 | Enrolling by invitation | Fernanda P Silveira, MD, MS | 385 | 2025-10-15 | 2026-09-29 |
| Corticosteroids for PJP in Non-HIV Immunocompromised Adults Saline (0.9%, sterile, for infusion), Low Dose Corticosteroids, Moderate dose corticosteroids - Pneumocystis Jiroveci Pneumonia | Phase 3 | Not yet recruiting | Qingyuan Zhan | 240 | 2025-09-08 | 2025-09-09 |
| A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections. Fosmanogepix IV infusion, Standard of care antifungal therapy, Fosmanogepix oral tablet - Invasive Mold Infections | Phase 3 | Recruiting | Basilea Pharmaceutica | 234 | 2025-08-26 | 2026-10-28 |
| Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis Boric acid, Placebo - Vulvovaginal Candidiases, Vulvovaginal Candidiasis, Genital | Phase 3 | Completed | pH-D Feminine Health LLC | 333 | 2025-08-08 | 2026-10-23 |
| A Randomized Study of a Short Duration Therapy for Candidemia Standard of Care (SOC), Shortened duration of antifungal therapy - CANDIDEMIA | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 362 | 2025-07-01 | 2025-03-05 |
| Platform Trial For Cryptococcal Meningitis (PLATFORM-CM) Standard of care, Oteseconazole - antifungal therapy 1, Turletricin injection - antifungal therapy 2 - Hiv, Cryptococcal Meningitis | Phase 2 / Phase 3 | Recruiting | David Boulware | 2000 | 2025-05-28 | 2026-07-27 |
| Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution Working Amphotericine in liposome (Ambisome®) - Tinea Capitis | Phase 2 / Phase 3 | Active not recruiting | Sohag University | 30 | 2025-04-01 | 2025-05-20 |
| Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS Single high dose of liposomal amphotericin B, L-AmB standard dose - Disseminated Histoplasma Capsulatum Infection, AIDS and Infections | Phase 3 | Recruiting | Federal University of Health Science of Porto Alegre | 279 | 2025-01-16 | 2026-07-27 |
| A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis. Fosmanogepix, Caspofungin, Fluconazole - Candidemia, Candidiasis, Invasive | Phase 3 | Recruiting | Basilea Pharmaceutica | 450 | 2024-12-11 | 2026-10-19 |
| Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spray Dupilumab - Allergic Fungal Rhinosinusitis (AFRS), Chronic Rhinosinusitis (CRS) | Phase 3 | Withdrawn | National Institute on Deafness and Other Communication Disorders (NIDCD) | 2024-07-17 | 2024-07-25 | |
| Postbiotic as Adjunct Treatment for Vaginal Candidiasis Postbiotic, Placebo - Vaginal Candidiasis | Phase 2 / Phase 3 | Completed | Min-Tze LIONG | 99 | 2024-06-02 | 2026-07-07 |
| Efficacy and Safety of Clotrimazole+Lactulose Vaginal Suppositories Vs. Clotrimazole Monotherapy in Adult Women with Candidal Vaginitis/Vulvovaginitis Clotrimazole+Lactulose., Canesten (Clotrimazole), Lactulose - Candidal Vulvovaginitis (ICD-10 Code: B37.3), Vulvovaginal Candidiasis (VVC) | Phase 2 / Phase 3 | Recruiting | AVVA Pharmaceuticals Ltd. | 264 | 2024-02-29 | 2025-02-19 |
| A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis Prednisolone, Itraconazole - Allergic Bronchopulmonary Aspergillosis | Phase 3 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 300 | 2023-12-01 | 2025-02-28 |
| Add-on Dupilumab for AFRS as Postoperative Therapy (ADAPT) Dupilumab, Placebo, Intranasal Corticosteroid Sprays (INCS) - Allergic Fungal Rhinosinusitis | Phase 3 | Terminated | Emory University | 5 | 2023-10-26 | 2025-05-08 |
Showing 20 of 240. Sign in to see all of them.
HIV Infections (29) · Pneumonia, Pneumocystis (27) · Acquired Immunodeficiency Syndrome (26) · Candidiasis (26) · Candidiasis, Vulvovaginal (25) · Aspergillosis (21) · Onychomycosis (21) · Candidemia (20) · Tinea Pedis (19) · Candidiasis, Invasive (17) · Invasive Fungal Infections (17) · AIDS-Related Opportunistic Infections (12) · Aspergillosis, Allergic Bronchopulmonary (10) · Fungemia (9)
Bacterial Infections and Mycoses (240) · Infections (235) · Pathological Conditions, Signs and Symptoms (59) · Urogenital Diseases (59) · Genital Diseases (58) · Skin Diseases (58) · Skin and Connective Tissue Diseases (58) · Skin Diseases, Infectious (55) · Dermatomycoses (53) · Immune System Diseases (48) · Candidiasis (47) · Respiratory Tract Diseases (47) · Tinea (45) · Lung Diseases (44)
Fluconazole (38) · Voriconazole (24) · Caspofungin (17) · Amphotericin B (14) · Micafungin (13) · Trimethoprim, Sulfamethoxazole Drug Combination (13) · Itraconazole (12) · posaconazole (11) · Anidulafungin (10) · Terbinafine (10) · Clotrimazole (8) · liposomal amphotericin B (8) · Pentamidine (7) · ibrexafungerp (7) · Ketoconazole (6)
National Institute of Allergy and Infectious Diseases (NIAID) (22) · Pfizer (21) · Merck Sharp & Dohme LLC (14) · Astellas Pharma Inc (11) · Post Graduate Institute of Medical Education and Research, Chandigarh (11) · Scynexis, Inc. (7) · National Cancer Institute (NCI) (6) · Merz North America, Inc. (5) · University of Minnesota (4) · Children's Oncology Group (3) · Medicis Global Service Corporation (3) · Mycovia Pharmaceuticals Inc. (3) · Novartis (3) · Novartis Pharmaceuticals (3) · Salvat (3)
United States (118) · Canada (30) · France (26) · India (26) · Germany (24) · Brazil (22) · Spain (22) · Belgium (20) · Italy (20) · China (17) · Netherlands (16) · Russia (15) · Poland (13) · United Kingdom (13) · Greece (12)
David Angulo, MD (3) · Feinberg J (3) · Lawrence Parish, MD (3) · Ron Staugaard (3) · Daniel Piacquadio, MD (2) · El-Sadr W (2) · Fischl M (2) · Joanne Fraser, PhD (2)
PMID 28459966, PMID 28597967, PMID 33891293, PMID 31280481, PMID 36396498, PMID 19506188, PMID 21147825, PMID 23959319, PMID 25007364, PMID 33438477, PMID 36255448, PMID 37185921, PMID 38319878, PMID 15232472, PMID 16161031, PMID 17128343, PMID 17251530, PMID 17251531, PMID 17568028, PMID 17896299, PMID 17923538, PMID 18230259, PMID 18696746, PMID 18813103, PMID 19064840, PMID 19485785, PMID 19516120, PMID 19734762, PMID 19804626, PMID 19915602, PMID 20607114, PMID 20881664, PMID 21320967, PMID 21397541, PMID 21732834, PMID 21961941, PMID 21968664, PMID 22026929, PMID 22052309, PMID 22324990, PMID 22469884, PMID 22814329, PMID 23052987, PMID 23676114, PMID 23702779, PMID 23884486, PMID 24261608, PMID 24669841, PMID 24794367, PMID 24913161
2008 (4), U10CA095861 (3), 2009 (2), 2016 (2), 2017 (2), U10EY018573 (2), UG1CA189955 (2), 2015 (1), 2019 (1), R01HD057956 (1), R01NS086312 (1), U01AI068632 (1), U01AI125003 (1)