8 completed. 8 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 8 |
| Phase 2 | 2 | Completed 2 |
Follow Muscle Weakness: new trials by email Literature Review of Muscle Weakness trials Research Report on Muscle Weakness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Telitacicept in Generalized Myasthenia Gravis Telitacicept, Placebo - Myasthenia Gravis, Generalized | Phase 3 | Completed | RemeGen Co., Ltd. | 114 | 2023-03-28 | 2025-05-23 |
| Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) Elamipretide, Placebo - Mitochondrial Myopathies, Mitochondrial Pathology | Phase 3 | Completed | Stealth BioTherapeutics Inc. | 102 | 2022-04-29 | 2025-10-24 |
| Effect of PROGRESSive Training and Teststerone in Older Frail Men testosterone, Progressive muscle training - Muscle Weakness | Phase 2 / Phase 3 | Completed | University Hospital, Gentofte, Copenhagen | 192 | 2016-11-01 | 2024-05-29 |
| Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training Resistance exercise training, Creatine - Muscle Weakness | Phase 3 | Completed | University of Chile | 50 | 2014-10-01 | 2015-10-30 |
| Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex sugammadex 2mg/kg, neostigmine, sugammadex 4mg/kg - Diaphragmatic Dysfunction, Muscle Weakness | Phase 3 | Completed | University Hospital, Antwerp | 75 | 2013-10-01 | 2018-10-24 |
| The Effect of Alfacalcidol on Muscle Strength in Elderly Indonesian Women : A Randomized Controlled Trial alfacalcidol - Muscle Weakness | Phase 3 | Completed | Universitas Indonesia | 122 | 2012-04-01 | 2014-12-30 |
| Sedation Optimisation Strategy (S.O.S.) Ventilation Therapy strategy - Surgery, Critical Illness | Phase 3 | Completed | University Hospital, Montpellier | 140 | 2011-12-01 | 2015-12-02 |
| Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms Coenzyme Q10, Placebo - Pain, Weakness | Phase 2 / Phase 3 | Completed | Catherine Buettner | 68 | 2009-12-01 | 2017-01-23 |
Pain (2) · Agnosia (1) · Anxiety Disorders (1) · Asthenia (1) · Autoimmune Diseases (1) · Critical Illness (1) · Delirium (1) · Depression (1) · Mental Disorders (1) · Mitochondrial Diseases (1) · Mitochondrial Myopathies (1) · Mitochondrial complex I deficiency (1) · Motor Activity (1) · Multiple Endocrine Neoplasia Type 1 (1)
Muscular Diseases (8) · Musculoskeletal Diseases (8) · Neurologic Manifestations (8) · Neuromuscular Manifestations (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Nervous System Diseases (7) · Neuromuscular Diseases (3) · Behavior (2) · Disease Attributes (2) · Neoplasms (2) · Neoplasms by Site (2) · Atrophy (1) · Autoimmune Diseases of the Nervous System (1)
Autogenic Training (1) · Creatine (1) · Neostigmine (1) · Resistance Training (1) · Sugammadex (1) · Testosterone (1) · alfacalcidol (1) · arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide (1) · coenzyme Q10 (1) · telitacicept (1)
Catherine Buettner (1) · RemeGen Co., Ltd. (1) · Stealth BioTherapeutics Inc. (1) · Universitas Indonesia (1) · University Hospital, Antwerp (1) · University Hospital, Gentofte, Copenhagen (1) · University Hospital, Montpellier (1) · University of Chile (1)
United States (2) · Australia (1) · Belgium (1) · Chile (1) · China (1) · Denmark (1) · France (1) · Germany (1) · Hungary (1) · Indonesia (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Norway (1) · Spain (1)
Catherine Buettner, MD, MPH (1) · Gerald GC Chanques, MD, PhD (1) · Iin Anugrahini (1) · Karsten Overgaard, M.D. (1) · Sandra Hirsch, MD (1)
PMID 28935558, PMID 29500160, PMID 31629404, PMID 39289825
K23AR055664 (1)