1 completed, 1 recruiting. 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 1 | Completed 1 |
Follow Mitochondrial complex I deficiency: new trials by email Literature Review of Mitochondrial complex I deficiency trials Research Report on Mitochondrial complex I deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) Elamipretide, Placebo - Mitochondrial Myopathies, Mitochondrial Pathology | Phase 3 | Completed | Stealth BioTherapeutics Inc. | 102 | 2022-04-29 | 2025-10-24 |
| North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) Mitochondrial Disorders, Mitochondrial Genetic Disorders | Recruiting | Columbia University | 1000 | 2011-01-31 | 2026-02-04 |
Mitochondrial Diseases (2) · Mitochondrial Myopathies (2) · Ophthalmoplegia, Chronic Progressive External (2) · Acidosis, Lactic (1) · Barth Syndrome (1) · Brain Diseases (1) · Cytochrome-c Oxidase Deficiency (1) · Deafness (1) · Diabetes Mellitus (1) · Kearns-Sayre Syndrome (1) · Leigh Disease (1) · Leukoencephalopathies (1) · MELAS Syndrome (1) · MERRF Syndrome (1)
Chronic Disease (2) · Cranial Nerve Diseases (2) · Disease Attributes (2) · Eye Diseases (2) · Metabolic Diseases (2) · Muscular Diseases (2) · Musculoskeletal Diseases (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Neuromuscular Diseases (2) · Nutritional and Metabolic Diseases (2) · Ocular Motility Disorders (2) · Ophthalmoplegia (2) · Paralysis (2) · Pathologic Processes (2)
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide (1)
Columbia University (1) · Stealth BioTherapeutics Inc. (1)
United States (2) · Australia (1) · Canada (1) · Germany (1) · Hungary (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Norway (1) · Spain (1) · United Kingdom (1)
U54NS078059 (1)