3 terminated. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Terminated 3 |
| Phase 2 | 1 | Terminated 1 |
Follow Multiple System Atrophy: new trials by email Literature Review of Multiple System Atrophy trials Research Report on Multiple System Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure Droxidopa, Midodrine, Placebo - Autonomic Failure, Pure Autonomic Failure | Phase 1 | Terminated | Vanderbilt University Medical Center | 34 | 2016-09-01 | 2026-10-23 |
| Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure Losartan, Captopril, Placebo - Hypertension, Pure Autonomic Failure | Phase 1 | Terminated | Vanderbilt University | 12 | 2011-03-01 | 2018-08-24 |
| Augmenting Effects of L-DOPS With Carbidopa and Entacapone Droxidopa, Carbidopa, Entacapone - Parkinson Disease, Multiple System Atrophy | Phase 1 / Phase 2 | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 14 | 2007-10-01 | 2014-07-17 |
Parkinson Disease (2) · Pure Autonomic Failure (2) · Autonomic Nervous System Diseases (1) · Hypertension (1) · Hypotension, Orthostatic (1)
Basal Ganglia Diseases (3) · Brain Diseases (3) · Central Nervous System Diseases (3) · Movement Disorders (3) · Nervous System Diseases (3) · Neurodegenerative Diseases (3) · Primary Dysautonomias (3) · Synucleinopathies (3) · Autonomic Nervous System Diseases (2) · Cardiovascular Diseases (2) · Parkinsonian Disorders (2) · Vascular Diseases (2) · Hypotension (1) · Orthostatic Intolerance (1)
Droxidopa (2) · Captopril (1) · Carbidopa (1) · Losartan (1) · Midodrine (1) · entacapone (1)
National Institute of Neurological Disorders and Stroke (NINDS) (1) · Vanderbilt University (1) · Vanderbilt University Medical Center (1)
United States (3)
Italo Biaggioni, MD (2) · David S Goldstein, M.D. (1)