50 completed. 50 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 50 | Completed 50 |
Follow Mouth Abnormalities: new trials by email Literature Review of Mouth Abnormalities trials Research Report on Mouth Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Botulinum Toxin Injection in Reducing Scar Following Cheilorrhaphy. Modified Millard rotation advancement flap technique, botulinum toxin injection (BTX A) before surgical intervention - Unilateral Cleft Lip | Not applicable | Completed | Mansoura University | 32 | 2025-03-15 | 2026-07-22 |
| Improving the Outcomes of Nasoalveolar Molding in Complete Bilateral Cleft Lip and Palate Neonates Using a Modification in the Design of the Conventional Molding Appliance. vomer molding appliance, conventional molding appliance - Cleft Lip and Cleft Palate, Cleft Lip Bilateral | Not applicable | Completed | Tanta University | 20 | 2024-12-01 | 2026-09-11 |
| Conventional Versus Modified Pre-surgical Naso-Alveolar Molding Treatment in Cleft Lip and Palate Infants Nasoalveolar Molding, Addition silicone impression - Cleft Lip and/or Palate, Cleft Lip Bilateral | Not applicable | Completed | Mansoura University | 20 | 2024-06-16 | 2025-05-11 |
| Evaluating Salivary α - Amylase Levels Following Trigona Sp Honey Application To Post Palatoplasty Patients: A Pilot Randomized Clinical Study Trigona sp honey with the buccal fat pad technique, framicetyn sulfate dressing with the buccal fat pad technique, Trigona sp. honey dressing without the buccal fat pad technique - Buccal Fat Pad, Cleft Palate | Not applicable | Completed | Hasanuddin University | 24 | 2024-06-01 | 2026-05-28 |
| Evaluation of Efficiency the Full Digital Nasoalveolar Molding (F-D-NAM) on Nose and Lip Esthetics and Maxillary Arch Changes in Infants With Cleft Lip and Palate F-D-NAM - Cleft Lip and Palate | Not applicable | Completed | Cairo University | 14 | 2024-06-01 | 2026-06-22 |
| Customized Differential Palatal Expansion in Children With Cleft Lip and Palate Custom-Designed Palatal-Coverage Thermoplastic Aligner - Cleft Lip and Palate | Not applicable | Completed | Marmara University | 8 | 2024-05-07 | 2026-11-04 |
| Furlow With Buccinator and Velopharyngeal Function furlow with buccinator flap - Cleft Palate | Not applicable | Completed | Fayoum University | 40 | 2024-02-01 | 2024-04-30 |
| Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient closure of oro-nasal fistula in cleft palate patients - Cleft Palate | Not applicable | Completed | Tanta University | 36 | 2023-10-11 | 2026-09-29 |
| Outcome of Alar Base Support in Unilateral Secondary Cleft Lip and Nasal Deformity Repair With Dermal Roll Flap surgery - Cleft Lip, Nose; Anomaly | Not applicable | Completed | King Edward Medical University | 45 | 2023-10-01 | 2026-06-03 |
| Three Dimensional Evaluation of Dento-Skeletal Effects of Leaf Self Expander in Cleft Lip and Palate Patients Rapid maxillary expansion, Leaf Self Expander - Three Dimensional, Dento-Skeletal | Not applicable | Completed | Al-Azhar University | 20 | 2023-09-01 | 2026-02-03 |
| Comparison of Different Feeding Appliances for Cleft Palate Babies flexible feeding plate - Cleft Palate | Not applicable | Completed | Tanta University | 30 | 2023-07-01 | 2023-10-26 |
| Effect of Collagen Matrix Graft on Palatal Fistula Formation After Cleft Palate Repair Two-flap palatoplasty - Cleft Lip and Cleft Palate, Cleft Lip, Cleft Alveolus and Cleft Palate | Not applicable | Completed | Lagos State University | 48 | 2022-08-10 | 2024-10-09 |
| PACT Programme for Parents of Children With SHCN Prosocial-orientated Acceptance and Commitment Training plus positive parenting advice, Positive parenting advice - Urologic Diseases, Gastrointestinal Diseases | Not applicable | Completed | Chinese University of Hong Kong | 196 | 2022-06-27 | 2026-08-11 |
| Alveolar Cleft Repair Using Osteoinductive Ceramics Unilateral alveolar cleft repair - Cleft Palate Children, Cleft Alveolar Ridge | Not applicable | Completed | UMC Utrecht | 84 | 2022-06-01 | 2026-05-08 |
| LIMA Protocol Towards Palatal Fistula and Maxillary Growth in Cleft Palate LIMA protocol, RSCM Protocol - Cleft Palate, Fistula of Soft Palate (Disorder) | Not applicable | Completed | Universitas Indonesia | 35 | 2022-01-01 | 2025-08-22 |
| Evaluation of the Effect of Prosthetic Management for Congenital Cleft Lip and Palate Infants on the Middle Ear Function Feeding appliance - Cleft Lip and Palate | Not applicable | Completed | Alexandria University | 30 | 2021-10-01 | 2023-10-10 |
| The Effect of the Usage of Squeezable vs Standard Bottles After Cleft Palate Surgery on the Feeding Process of Infants Standart bottle, Squeezable bottle - Bottle Feeding | Not applicable | Completed | Acibadem University | 25 | 2021-09-28 | 2022-10-17 |
| Botulinum Toxin Injection in Reducing Lip Scar Following Cleft Lip Repair Botulinum, Fisher technique - Cleft Lip | Not applicable | Completed | Hams Hamed Abdelrahman | 22 | 2021-07-01 | 2022-10-04 |
| Unilateral Cleft Lip Repair : Modified Millard and Mishra Technique Unilateral cleft lip repair - Cleft Lip | Not applicable | Completed | Cairo University | 42 | 2021-04-01 | 2023-02-28 |
| The Effect of a Newly Designed Presurgical Orthopedic Appliance Active PSIO - Cleft Lip and Palate | Not applicable | Completed | University of Baghdad | 30 | 2021-01-01 | 2022-09-21 |
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Cleft Lip (27) · Cleft Palate (26) · Velopharyngeal Insufficiency (4) · Cicatrix (2) · Congenital Abnormalities (2) · Microstomia (2) · Scleroderma, Systemic (2) · Articulation Disorders (1) · Attention Deficit Disorder with Hyperactivity (1) · Autism Spectrum Disorder (1) · Bottle Feeding (1) · Communication Disorders (1) · Deglutition Disorders (1) · Developmental Disabilities (1) · Gastrointestinal Diseases (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (50) · Mouth Diseases (50) · Stomatognathic Diseases (50) · Stomatognathic System Abnormalities (50) · Congenital Abnormalities (48) · Lip Diseases (27) · Craniofacial Abnormalities (26) · Jaw Abnormalities (26) · Jaw Diseases (26) · Maxillofacial Abnormalities (26) · Musculoskeletal Abnormalities (26) · Musculoskeletal Diseases (26) · Pathological Conditions, Signs and Symptoms (8) · Nervous System Diseases (5)
Nasoalveolar Molding (2) · Acetaminophen (1) · Alveolar Bone Grafting (1) · Botulinum Toxins (1) · Palatal Expansion Technique (1) · Surgical Procedures, Operative (1) · Surveys and Questionnaires (1) · cyclopropapyrroloindole (1) · osteovit (1)
Cairo University (8) · Mansoura University (3) · Tanta University (3) · Alexandria University (2) · Hams Hamed Abdelrahman (2) · University of Pittsburgh (2) · Acibadem University (1) · Al-Azhar University (1) · Alaa Mamdouh (1) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Children's Hospital Medical Center, Cincinnati (1) · Children's Mercy Hospital Kansas City (1) · Chinese University of Hong Kong (1) · Cukurova University (1)
Egypt (23) · United States (5) · Brazil (3) · France (3) · Turkey (Türkiye) (3) · Indonesia (2) · Norway (2) · Canada (1) · Denmark (1) · Hong Kong (1) · Iraq (1) · Netherlands (1) · Nigeria (1) · Pakistan (1) · Sweden (1)
Basel Saeed Shamaa, Master's (1) · Chelan Nour, MD (1) · Cuneyt M Alper, MD (1) · Damiano DC Abeni, MD, MPH (1) · Daniel Grossoehme (1) · Daniela F Bueno, PhD (1) · Engy S Elhakeem, PhD (1) · Jeff Murray, M.D. (1) · Jennifer Szczepaniak, BS (1) · Kasr Elainy (1) · Kevin J Munro (1)
PMID 16563165, PMID 21328261, PMID 21948638, PMID 22204448, PMID 24705041, PMID 25206201, PMID 26997574, PMID 31300507, PMID 31860800, PMID 32256610, PMID 33397459, PMID 35100923, PMID 35303932, PMID 36126199, PMID 37646677, PMID 39791255, PMID 41930721
2014 (1), R01DC011524 (1), U01DE018837 (1), U01HD040561 (1)