39 completed, 6 terminated, 5 unknown, 3 withdrawn. 20 Phase 2, 16 Phase 1, 6 Not applicable, 5 Phase 4, 4 Phase 3.
Follow Methamphetamine Dependence: new trials by email Literature Review of Methamphetamine Dependence trials Research Report on Methamphetamine Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| rTMS for Stimulant Use Disorders rTMS, Sham (Placebo) - Cocaine Use Disorder, Methamphetamine Abuse | Not applicable | Completed | Medical University of South Carolina | 129 | 2022-02-04 | 2025-07-03 |
| Creatine for Depressed Male and Female Methamphetamine Users Creatine monohydrate - Depression, Anxiety | Phase 3 | Recruiting | Montana State University | 29 | 2015-11-01 | 2015-12-11 |
| Pilot Study of Entacapone for Methamphetamine Abuse Entacapone, Methamphetamine, Placebo - Methamphetamine Dependence | Early Phase 1 | Completed | Oregon Health and Science University | 29 | 2014-06-01 | 2019-09-12 |
| Clinical Efficacy of Lisdexamfetamine for Methamphetamine Dependence Lisdexamfetamine, Placebo - Methamphetamine Dependence | Phase 1 | Completed | University of Arkansas | 19 | 2014-02-01 | 2017-08-22 |
| Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine Abuse Methamphetamine (Desoxyn®) - Methamphetamine Abuse, Methamphetamine Dependence | Early Phase 1 | Completed | University of Kentucky | 24 | 2013-10-01 | 2018-09-14 |
| Trial of Ibudilast for Methamphetamine Dependence Ibudilast, Placebo - Methamphetamine Dependence, HIV Infection | Phase 2 | Completed | University of California, Los Angeles | 125 | 2013-07-01 | 2019-01-30 |
| Buspirone as a Candidate Medication for Methamphetamine Abuse Methamphetamine, Placebo - Methamphetamine Dependence, Methamphetamine Abuse | Phase 1 | Completed | University of Kentucky | 9 | 2013-04-01 | 2018-02-07 |
| An Study of Paliperidone Extended-Release Tablets in the Treatment of Methamphetamine Dependence Paliperidone, placebo - Methamphetamine Dependence | Not applicable | Completed | Wei Hao | 80 | 2013-02-01 | 2017-07-13 |
| A Comparison of Paliperidone and Risperidone for Treatment of Patirnts With Methamphetamine-Associated Psychosis paliperidone, Risperidone - Methamphetamine Dependence | Phase 4 | Completed | Wei Hao | 120 | 2013-02-01 | 2015-02-04 |
| An Study of Aripiprazole in the Treatment of Methamphetamine Dependence Aripiprazole, placebo - Methamphetamine Dependence | Phase 4 | Terminated | Wei Hao | 10 | 2012-09-01 | 2015-02-04 |
| A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis Risperidone, Aripiprazole - Methamphetamine Dependence | Phase 4 | Terminated | Wei Hao | 50 | 2012-07-01 | 2015-02-04 |
| Comparison of Methamphetamine-Dependent and Healthy Volunteers Using a Web-Enabled Cognitive Neuropsychological Evaluation System Web-Enabled Cognitive Neuropsychological Evaluation System - Methamphetamine Dependence | Not applicable | Unknown | California Pacific Medical Center Research Institute | 32 | 2012-04-01 | 2013-08-09 |
| Clinical Efficacy of Atomoxetine for Methamphetamine Dependence Atomoxetine, placebo - Methamphetamine Dependence | Phase 1 / Phase 2 | Completed | University of Arkansas | 20 | 2012-04-01 | 2017-02-09 |
| A Cognitive Behavioral Therapy-Based Text Messaging Intervention for Methamphetamine Dependence Text messages - Methamphetamine Dependence | Phase 1 | Completed | New Leaf Treatment Center | 25 | 2012-04-01 | 2013-07-10 |
| Varenicline for Methamphetamine Dependence Varenicline, Placebo - Methamphetamine Dependence, Substance Abuse | Phase 2 | Completed | University of California, Los Angeles | 52 | 2012-02-01 | 2018-01-18 |
| A Randomized, Placebo-Controlled Trial of Modafinil for Methamphetamine Dependence Modafinil - Methamphetamine Dependence | Phase 2 | Completed | California Pacific Medical Center Research Institute | 72 | 2011-10-01 | 2013-07-02 |
| PHASE IIA: Trial of a Novel Ondansetron Formulation (OND-PR002) and Immediate-Release Methylphenidate (Ritalin®)(OND003IND) OND-PR002 and MPh-IR, Placebo: Two dextrose capsules for Ond-PR002 and MPh-IR - Methamphetamine Dependence, Cocaine Dependence | Phase 2 | Completed | Tong Lee | 30 | 2011-08-01 | 2014-10-07 |
| Phase 1 Naltrexone-Bupropion-Methamphetamine Interaction Study placebo, Naltrexone and Bupropion SR - Methamphetamine Dependence | Phase 1 | Completed | National Institute on Drug Abuse (NIDA) | 16 | 2011-08-01 | 2017-01-12 |
| Varenicline as a Treatment for Methamphetamine Dependence Placebo, Varenicline - Methamphetamine Dependence, Methamphetamine Abuse | Phase 1 | Completed | Baylor College of Medicine | 17 | 2011-01-01 | 2013-06-13 |
| Combination of Psychosocial Intervention and Slow Prosecutions for the Treatment of Methamphetamine Abuse/Dependence Psychosocial intervention, Telephone reminding - Amphetamine Abuse, Amphetamine Dependence | Not applicable | Unknown | National Taiwan University Hospital | 60 | 2011-01-01 | 2011-01-10 |
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Substance-Related Disorders (13) · Behavior, Addictive (7) · Cocaine-Related Disorders (4) · Amphetamine-Related Disorders (2) · Anxiety Disorders (1) · Bipolar Disorder (1) · Depression (1) · HIV Infections (1) · Recurrence (1) · Smoking Cessation (1) · Tobacco Use Disorder (1)
Mental Disorders (18) · Chemically-Induced Disorders (17) · Behavior (9) · Compulsive Behavior (7) · Impulsive Behavior (7) · Substance-Related Disorders (4) · Behavioral Symptoms (1) · Bipolar and Related Disorders (1) · Blood-Borne Infections (1) · Communicable Diseases (1) · Disease Attributes (1) · Genital Diseases (1) · Health Behavior (1) · Immune System Diseases (1) · Immunologic Deficiency Syndromes (1)
Sugars (9) · Modafinil (6) · Varenicline (4) · Aripiprazole (3) · Methamphetamine (3) · Methylphenidate (3) · Naltrexone (3) · Risperidone (3) · Acetylcysteine (2) · Atomoxetine Hydrochloride (2) · Bupropion (2) · Cytidine Diphosphate Choline (2) · Lobeline (2) · Paliperidone Palmitate (2) · Quetiapine Fumarate (2)
University of Arkansas (8) · University of California, Los Angeles (7) · Baylor College of Medicine (6) · National Institute on Drug Abuse (NIDA) (5) · Wei Hao (4) · California Pacific Medical Center Research Institute (3) · Medical University of South Carolina (3) · University of Cincinnati (2) · University of Kentucky (2) · Catalyst Pharmaceuticals, Inc. (1) · Montana State University (1) · National Taiwan University Hospital (1) · New Leaf Treatment Center (1) · Oregon Health and Science University (1) · Perry Renshaw (1)
United States (45) · China (4) · Canada (1) · South Korea (1) · Taiwan (1)
Wei Hao, MD., Ph.D. (4) · Alison Oliveto, PhD (3) · Steven Shoptaw, PhD (3) · Reese Jones, M.D. (2) · Richard De La Garza, II, PhD (2) · Ahmed Elkashef, M.D. (1) · Andrew J Saxon (1) · Ashwin A Patkar, MD (1) · Bryan K Tolliver, MD, PhD (1) · Charles W Gorodetzky, MD, PhD (1) · Douglas Polcin, Ed.D. (1) · Dr. Janette McGaugh, MD (1) · Edward Sellers, MD, PhD (1) · Eugene Somoza, MD, PhD (1) · Gantt Galloway, PharmD (1)
PMID 18681757, PMID 20092966, PMID 21840138, PMID 22217949, PMID 22445683, PMID 24028801, PMID 24075226, PMID 24128381, PMID 24345356, PMID 24393456, PMID 24894963, PMID 24930359, PMID 29860057, PMID 30466549, PMID 32296355, PMID 40336040
P50DA018185 (5), P50DA018197 (3), R01DA027134 (2), 1RC2DA028905-01 (1), K23DA023558 (1), P20DA022658 (1), R01DA023468 (1), R01DA023964 (1), R01DA035054 (1), R21DA024756 (1), R21DA034824 (1), R21DA035481 (1), U10DA013732 (1), UG1DA013727 (1)