12 completed, 3 recruiting, 2 not yet recruiting, 1 terminated. 6 Early Phase 1, 5 Phase 1, 3 Phase 4, 2 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 6 | Completed 5, Recruiting 1 |
| Phase 1 | 5 | Completed 4, Terminated 1 |
| Phase 4 | 3 | Completed 2, Not yet recruiting 1 |
| Not applicable | 2 | Completed 1, Not yet recruiting 1 |
| Phase 2 | 2 | Recruiting 2 |
Follow Methamphetamine: new trials by email Literature Review of Methamphetamine trials Research Report on Methamphetamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-term Effects of Methamphetamine on Residual Latent HIV Disease Study Oral Methamphetamine, Placebo oral capsule - HIV -1 Infection, Methamphetamine Use | Phase 4 | Not yet recruiting | University of California, San Francisco | 20 | 2026-10-01 | 2026-08-17 |
| Methamphetamine, PrEP, and Intersectional Stigma Study Methamphetamine, PrEP, and Intersectional Stigma (eMPrISe) study - Methamphetamine Abuse, Hiv | Not applicable | Not yet recruiting | Arizona State University | 20 | 2026-04-15 | 2026-02-19 |
| A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine Methamphetamine, Sterile Saline, CS-1103 - Methamphetamine Intoxication, Methamphetamine Disorders | Phase 2 | Recruiting | Clear Scientific, Inc. | 40 | 2026-02-05 | 2026-10-21 |
| MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study) 3,4-Methyl enedioxy methamphetamine, Methamphetamine, Cognitive Behavioral Therapy (CBT) - Obsessive-Compulsive Disorder | Phase 2 | Recruiting | Carolyn Rodriguez | 40 | 2025-09-10 | 2026-03-05 |
| Methamphetamine and Troriluzole Placebo, Methamphetamine - Methamphetamine Use Disorder | Early Phase 1 | Recruiting | William Stoops | 40 | 2025-08-25 | 2026-06-08 |
| Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function MDMA, Methamphetamine, placebo oral tablet - Stimulant Use, MDMA ('Ecstasy') | Early Phase 1 | Completed | University of Chicago | 43 | 2022-05-11 | 2024-01-24 |
| Brain Function and EEG Methamphetamine, Placebo - Healthy, Mood | Early Phase 1 | Completed | University of Chicago | 40 | 2021-07-01 | 2024-01-24 |
| Mirtazapine and Methamphetamine Drug-drug Interaction Study Mirtazapine, Methamphetamine - Methamphetamine Use Disorder, Drug Interaction | Phase 1 | Completed | San Francisco Department of Public Health | 15 | 2021-05-03 | 2024-09-27 |
| Effect of Methamphetamine on Residual Latent HIV Disease Study Oral Methamphetamine, Placebo oral capsule - HIV-1-infection, Methamphetamine-dependence | Phase 4 | Completed | University of California, San Francisco | 14 | 2021-01-01 | 2026-04-09 |
| Drugs Brain and Behavior (DDP) Methamphetamine, placebo oral tablet - Stimulant Use | Early Phase 1 | Completed | University of Chicago | 138 | 2020-11-01 | 2025-01-09 |
| Behavioral Effects of Drugs (Inpatient): 40 [Methamphetamine, Methylphenidate, Duloxetine] Methamphetamine, Methylphenidate, Placebo oral capsule - Methamphetamine Use Disorder | Phase 1 | Completed | Craig Rush | 8 | 2019-09-01 | 2023-01-09 |
| Effects of Genotype on Resting State Connectivity During Methamphetamine Administration Magnetic resonance imaging (MRI), Methamphetamine Hydrochloride Tablets, Placebo oral tablet - Methamphetamine-dependence | Phase 4 | Completed | Oregon Health and Science University | 69 | 2019-08-16 | 2024-11-15 |
| Study of Pomaglumetad and Methamphetamine Pomaglumetad methionil, Placebo, Methamphetamine - Methamphetamine Use Disorder | Phase 1 | Terminated | University of California, Los Angeles | 19 | 2017-08-01 | 2020-09-01 |
| Effect of Stimulant Drugs on Social Perception 3,4-Methylenedioxymethamphetamine, methamphetamine - Healthy, MDMA ('Ecstasy') | Phase 1 | Completed | University of Chicago | 36 | 2016-06-01 | 2024-01-05 |
| Acquisition of Responses to a Methamphetamine-associated Cue in Healthy Humans methamphetamine, placebo - Substance Abuse | Not applicable | Completed | University of Chicago | 90 | 2014-07-01 | 2018-07-26 |
| Pilot Study of Entacapone for Methamphetamine Abuse Entacapone, Methamphetamine, Placebo - Methamphetamine Dependence | Early Phase 1 | Completed | Oregon Health and Science University | 29 | 2014-06-01 | 2019-09-12 |
| Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine Abuse Methamphetamine (Desoxyn®) - Methamphetamine Abuse, Methamphetamine Dependence | Early Phase 1 | Completed | University of Kentucky | 24 | 2013-10-01 | 2018-09-14 |
| Buspirone as a Candidate Medication for Methamphetamine Abuse Methamphetamine, Placebo - Methamphetamine Dependence, Methamphetamine Abuse | Phase 1 | Completed | University of Kentucky | 9 | 2013-04-01 | 2018-02-07 |
Acquired Immunodeficiency Syndrome (1) · Cardiovascular Abnormalities (1) · Inflammation (1) · Obsessive-Compulsive Disorder (1) · Social Behavior (1) · Social Stigma (1) · Substance-Related Disorders (1)
University of Chicago (5) · Oregon Health and Science University (2) · University of California, San Francisco (2) · University of Kentucky (2) · Arizona State University (1) · Carolyn Rodriguez (1) · Clear Scientific, Inc. (1) · Craig Rush (1) · San Francisco Department of Public Health (1) · University of California, Los Angeles (1) · William Stoops (1)
United States (16)
Harriet de Wit (2) · Carolyn Rodriguez, MD, PhD (1) · Jonathan C Fellers, MD (1) · Keith Heinzerling, MD (1) · Leah Mayo (1) · Phillip Coffin, MD, MIA (1) · Sulggi A Lee, MD PhD (1) · Sulggi Lee, MD, PhD (1) · William F Hoffman, MD, PhD (1) · William Hoffman, MD, PhD (1) · Xinhua Li, Ph.D. (1)
R01DA002812 (1), R01DA043238 (1), R01DA047391 (1), R01DA060632 (1), R21DA035481 (1), R61DA047024 (1), RM1DA063218 (1), U01DA058548 (1)