13 completed, 7 recruiting, 4 unknown, 2 active not recruiting. 28 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 28 | Completed 13, Recruiting 7, Unknown 4, Active not recruiting 2, Terminated 2 |
Follow Major Depressive Episode: new trials by email Literature Review of Major Depressive Episode trials Research Report on Major Depressive Episode
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Signature Response to Light Therapy in Unipolar and Bipolar Major Depressive Episode (MDE) Light therapy - Major Depressive Episode | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 173 | 2026-06-17 | 2026-08-12 |
| tDCS: Sleep to Mood in Depression (S2M-D) transcranial direct current stimulation (tDCS) - Major Depressive Disorder, MDD | Not applicable | Recruiting | NYU Langone Health | 35 | 2026-06-04 | 2026-06-08 |
| Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD) 60Hz Intermittent Light Therapy, Sham Light Therapy - Depression, MDD | Not applicable | Active not recruiting | NYU Langone Health | 44 | 2025-08-18 | 2026-11-05 |
| Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents MagPro X100 edition (MagVenture, Skovlunde, Denmark) - Major Depressive Disorder, Depression in Adolescence | Not applicable | Recruiting | University of Texas at Austin | 40 | 2025-04-01 | 2026-08-19 |
| The Impact of Coach-guided Risk Communication on the Risk of Major Depression coach-guided personalized depression risk communication, depression risk information - Major Depressive Episode, Risk Reduction | Not applicable | Recruiting | Dalhousie University | 1000 | 2025-02-10 | 2025-09-02 |
| At-Home tDCS as Maintenance Therapy tDCS - MDD, Severe Depression | Not applicable | Recruiting | Technical University of Munich | 30 | 2024-10-01 | 2025-12-08 |
| A Text Messaging Intervention to Reduce Perinatal Depression Risk Text Messaging Intervention - Major Depressive Episode | Not applicable | Completed | University of Massachusetts, Worcester | 40 | 2024-09-05 | 2026-01-27 |
| Metabolomics During ElectroConvulsivoTherapy Electroconvulsive therapy - Major Depressive Episode, ECT | Not applicable | Recruiting | Hôpital le Vinatier | 50 | 2024-03-11 | 2025-07-24 |
| Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics Intermittent Theta Burst Transcranial Magnetic Stimulation (Active), Intermittent Theta Burst Transcranial Magnetic Stimulation (Sham) - Major Depressive Episode, Borderline Personality Disorder | Not applicable | Completed | Massachusetts General Hospital | 75 | 2023-11-01 | 2026-07-14 |
| The RAFT ECT Study Frontoparietal Ultrabrief Right Unilateral (UBRUL-FP) electroconvulsive therapy, Temporoparietal Ultrabrief Right Unilateral (UBRUL-TP) electroconvulsive therapy - Major Depressive Episode | Not applicable | Completed | The George Institute | 156 | 2023-03-22 | 2026-03-13 |
| Personalized Repetitive Transcranial Magnetic Stimulation Treatment for Major Depressive Episode Active rTMS, Sham rTMS - Major Depressive Episode | Not applicable | Completed | Jiangsu Province Nanjing Brain Hospital | 219 | 2022-08-02 | 2025-03-06 |
| Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) Treatment for Major Depressive Episode High-Definition Transcranial Direct Current Stimulation (HD-tDCS), Antipsychotics, mood stabilizers, etc. - Major Depressive Episode | Not applicable | Unknown | Jiangsu Province Nanjing Brain Hospital | 120 | 2022-04-01 | 2023-10-18 |
| Affective Touch, Hedonia and Suicidal Behavior Tactile stimulation - Major Depressive Episode, Suicidal and Self-injurious Behavior | Not applicable | Completed | University Hospital, Montpellier | 72 | 2022-02-11 | 2025-01-10 |
| Left vs. Right Non-Inferiority Trial Repetitive Transcranial Magnetic Stimulation, Intermittent Theta Burst Stimulation (iTBS), Low Frequency Right (LFR) - Depression, Major Depressive Disorder | Not applicable | Recruiting | University of British Columbia | 480 | 2021-11-08 | 2026-08-25 |
| Patient-oriented Randomized Pragmatic Feasibility Trial With rTMS in Depression and Anxiety Repetitive Transcranial Magnetic Stimulation - Major Depressive Episode, Major Depressive Disorder | Not applicable | Active not recruiting | University of British Columbia | 100 | 2021-10-11 | 2026-08-25 |
| Predict MDE Outcomes After MST Magpro X100 + Option, ThymatronSystem Ⅳ Electroconvulsive System - Major Depressive Episode | Not applicable | Completed | Shanghai Mental Health Center | 45 | 2020-07-20 | 2023-10-31 |
| Comparing Uni- and Bi-lateral TBS in Major Depression Theta burst stimulation - Major Depressive Episode | Not applicable | Unknown | The Royal Ottawa Mental Health Centre | 256 | 2019-12-12 | 2023-12-04 |
| Validation Study: Mobile DSST on Cognition in Adults With MDD Pen and Paper Digit Symbol Substitution Test (DSST), Electronic Digit Symbol Substitution Test (DSST)- (a.k.a. Codebreaker) - Major Depressive Episode | Not applicable | Completed | Brain and Cognition Discovery Foundation | 30 | 2019-08-25 | 2020-07-08 |
| Stress Systems and Psychotherapy in Depression internet-based intervention for mild to moderate depression - Major Depressive Episode | Not applicable | Completed | Freie Universität Berlin | 42 | 2018-11-20 | 2020-10-23 |
| Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder Universal Screening Arm - Major Depressive Disorder, Major Depressive Episode | Not applicable | Completed | Milton S. Hershey Medical Center | 12909 | 2018-11-06 | 2024-01-11 |
Showing 20 of 28. Sign in to see all of them.
Depression (10) · Depressive Disorder, Major (10) · Suicide (4) · Depressive Disorder, Treatment-Resistant (2) · Borderline Personality Disorder (1) · Depressive Disorder (1) · Inflammation (1) · Psychological Well-Being (1) · Recurrence (1) · Risk Reduction Behavior (1) · Self-Injurious Behavior (1)
Behavior (13) · Behavioral Symptoms (12) · Mental Disorders (12) · Mood Disorders (11) · Depressive Disorder (10) · Self-Injurious Behavior (3) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Disease Attributes (1) · Personal Satisfaction (1) · Personality Disorders (1)
Blood Specimen Collection (3) · Electroconvulsive Therapy (2) · Transcranial Direct Current Stimulation (2) · Transcranial Magnetic Stimulation (2) · Antipsychotic Agents (1) · Fatty Acids, Omega-3 (1) · Fish Oils (1) · Hematologic Tests (1) · Magnetic Resonance Spectroscopy (1) · Phototherapy (1) · Psychotherapy (1) · penclomedine (1)
University Hospital, Montpellier (3) · Assistance Publique - Hôpitaux de Paris (2) · Jiangsu Province Nanjing Brain Hospital (2) · NYU Langone Health (2) · University of British Columbia (2) · Assistance Publique Hopitaux De Marseille (1) · Brain and Cognition Discovery Foundation (1) · Dalhousie University (1) · Freie Universität Berlin (1) · Hôpital le Vinatier (1) · Massachusetts General Hospital (1) · Milton S. Hershey Medical Center (1) · National Science and Technology Council, Taiwan (1) · Philipps University Marburg (1) · Shanghai Mental Health Center (1)
United States (8) · France (6) · Canada (5) · Germany (4) · China (3) · Australia (1) · Taiwan (1)
Fei Wang (2) · Fidel Vila-Rodriguez, MD, PhD (2) · Anthony Rodgers (1) · Colleen Loo (1) · Deepa Sekhar, MD (1) · Frank Jessen, Prof.Dr. (1) · Giuseppina Pilloni (1) · Giuseppina Pilloni, PhD (1) · JianLi Wang, PhD (1) · Jianhua Sheng, PHD (1) · Joan Camprodon, MD/PhD (1) · Kimberly Yonkers, MD (1) · Kuan-Pin Su, MD PhD (1)
PMID 11940851, PMID 1260078, PMID 24602409, PMID 25592385, PMID 29436330, PMID 29536616, PMID 31675086, PMID 31881995, PMID 34739064, PMID 35944722, PMID 36301615, PMID 37817124, PMID 38619842, PMID 38968425, PMID 39696180, PMID 39884877, PMID 40669702
R34MH130934 (1)