25 completed, 8 unknown, 6 terminated, 4 recruiting. 13 Not applicable, 9 Phase 4, 7 Phase 3, 3 Phase 2, 1 Early Phase 1.
Follow Antipsychotic Agents: new trials by email Literature Review of Antipsychotic Agents trials Research Report on Antipsychotic Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A) - Wounds and Injuries, Out-of-Hospital Cardiac Arrest | Active not recruiting | Azienda Usl di Bologna | 52720 | 2026-06-10 | 2026-10-20 | |
| Long-Term Real-World Safety of Cobenfy in Adults With Schizophrenia xanomeline-trospium chloride, Oral antipsychotics - Schizophrenia | Active not recruiting | Bristol-Myers Squibb | 3000 | 2026-05-01 | 2026-08-24 | |
| Pharmacologic Treatment in Legal Offenders With Schizophrenia, a Prospective Observational Mirror Image Study. Antipsychotic - Schizophrenia | Withdrawn | Psychiatric University Hospital, Zurich | 2025-12-01 | 2025-12-08 | ||
| Effect of Cognitive Behavioral Therapy on Auditory Hallucinations and NLR in Schizophrenia Patients Cognitive Behavioral Therapy (CBT), risperidone - Schizophrenia Patients, Auditory Hallucination | Not applicable | Completed | Hasanuddin University | 50 | 2025-11-01 | 2026-04-17 |
| HD-tDCS for Adolescent Bipolar Depression Targeting S1 Active HD-tDCS, Antipsychotics, mood stabilizers, etc., Sham HD-tDCS - Adolescent, Bipolar Depression | Not applicable | Recruiting | Jiangsu Province Nanjing Brain Hospital | 100 | 2025-09-16 | 2025-11-24 |
| A Clinical Trial of Adjunctive Thyroxine for Avolition in Schizophrenia Antipsychotics plus Levothyroxine Sodium, Antipsychotics plus Placebo - Schizophrenia, Avolition | Early Phase 1 | Not yet recruiting | Peking University | 90 | 2025-07-01 | 2025-06-10 |
| The ATP Project (Antipsychotic-TEP-Psychosis) Antipsychotic drugs - First Episose Psychosis, Metabolic Disease | Not yet recruiting | Université de Sherbrooke | 18 | 2024-11-01 | 2024-11-08 | |
| Magnetic Seizure Therapy for Psychotic Disorders Magnetic seizure therapy by Magnetic stimulator, Antipsychotic medications (such as olanzpine, risperidone, aripiprazole, quetiapine, amisulpride, etc) - Psychotic Disorders | Not applicable | Recruiting | Shanghai Jiao Tong University School of Medicine | 50 | 2024-09-01 | 2025-11-25 |
| Maternal And Infant Antipsychotic Study Antipsychotics, Non-antipsychotic medication, No Medication - Antipsychotics, Pregnancy | Recruiting | Icahn School of Medicine at Mount Sinai | 74 | 2023-09-29 | 2026-06-22 | |
| An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine Clozapine, Antipsychotics,Other (non-Clozapine) - Treatment-resistant Schizophrenia | Phase 4 | Terminated | Ohio State University | 5 | 2023-08-16 | 2026-02-25 |
| Side Effects of Psychiatric Medications - a Nested Case Control Cohort Historical Prospective Study Psychiatric Drugs - Psychotic Disorders | Unknown | Mark Weiser, MD, Principal Investigator | 22777 | 2023-03-26 | 2024-03-04 | |
| Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) Treatment for Major Depressive Episode High-Definition Transcranial Direct Current Stimulation (HD-tDCS), Antipsychotics, mood stabilizers, etc. - Major Depressive Episode | Not applicable | Unknown | Jiangsu Province Nanjing Brain Hospital | 120 | 2022-04-01 | 2023-10-18 |
| Psychotherapy for Psychosis, Adverse Events, and Substance Misuse Prolonged exposure (PE)+ therapy, Treatment as usual (TAU) - Psychotic Disorders, Stress Disorders, Traumatic | Not applicable | Completed | Nova Scotia Health Authority | 19 | 2021-11-15 | 2023-11-29 |
| A Study on the Brain Mechanism of cTBS in Improving Medication-resistant Auditory Hallucinations in Schizophrenia Antipsychotic drugs, cTBS(the left temporoparietal cortex as the stimulation target), cTBS (the left cerebellum Crus II as the stimulation target) - Schizophrenia | Not applicable | Completed | Central South University | 200 | 2021-09-09 | 2024-08-21 |
| Synergistic Effect of Vitamin E & D in Reducing Risk of Effects Associated With Atypical Anti-psychotics Risperidone, Olanzapine, Quetiapine - Antipsychotics and Neuroleptics Toxicity | Not applicable | Completed | Dr Rabia Arshad | 140 | 2021-01-01 | 2024-01-11 |
| Monitoring of Arrhythmias in Patients Treated With Antipsychotics Antipsychotic - Death, Sudden, Cardiac, Arrythmia | Not applicable | Unknown | Herlev and Gentofte Hospital | 600 | 2021-01-01 | 2021-02-21 |
| Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental Disorders Antipsychotic drugs, Mood stabilizer, Paroxetine - Common Mental Disorder | Not applicable | Completed | Central South University | 200 | 2020-01-15 | 2024-08-21 |
| Efficacy of Electroencephalography (EEG) Neurofeedback (NF) for the Treatment of Anxiety Disorder SSRI or SNRI or benzodiazepines or tricyclic antidepressants or other antidepressants or antipsychotics or other sedative-hypnotics, Neurofeedback system - Anxiety Disorder, Healthy | Not applicable | Unknown | Tianjin Anding Hospital | 60 | 2019-09-10 | 2021-10-19 |
| Prolactin Change in Chinese Patients With Schizophrenia After Antipsychotics Treatment Antipsychotic - Schizophrenia, Antipyretics Toxicity | Completed | Shanghai Mental Health Center | 10363 | 2019-06-06 | 2022-10-27 | |
| A Study for Schizophrenia Relapse Prediction Oral Antipsychotics (OAP) - Schizophrenia | Completed | Janssen Research & Development, LLC | 333 | 2018-11-29 | 2025-04-27 |
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Schizophrenia (28) · Psychotic Disorders (11) · Bipolar Disorder (6) · Depression (3) · Mental Disorders (3) · Autism Spectrum Disorder (2) · Depressive Disorder, Major (2) · Schizophrenia Spectrum and Other Psychotic Disorders (2) · Anxiety Disorders (1) · Arrhythmias, Cardiac (1) · Attention Deficit Disorder with Hyperactivity (1) · Autistic Disorder (1) · Brain Injuries, Traumatic (1) · Child Development Disorders, Pervasive (1) · Death, Sudden, Cardiac (1)
Central South University (2) · Janssen Research & Development, LLC (2) · Janssen-Cilag International NV (2) · Janssen-Cilag, S.A. (2) · Jiangsu Province Nanjing Brain Hospital (2) · University of Illinois at Chicago (2) · Amsterdam UMC, location VUmc (1) · Azienda Usl di Bologna (1) · Beth Israel Deaconess Medical Center (1) · Bristol-Myers Squibb (1) · Child Psychopharmacology Institute (1) · Dr Rabia Arshad (1) · Duke University (1) · FDA Office of Orphan Products Development (1) · Fundación Pública Andaluza Progreso y Salud (1)
United States (12) · China (9) · Spain (5) · Canada (4) · Germany (4) · Bulgaria (3) · Czechia (3) · Russia (3) · South Korea (3) · Austria (2) · Belgium (2) · France (2) · Greece (2) · Israel (2) · Italy (2)
Fei Wang (2) · Wenbin Guo (2) · Bill J Duke, M.A., Ph.D. (1) · Casper Bang, MD, PhD (1) · Huafang Li, MD, PhD (1)
PMID 21270143, PMID 21366475, PMID 21514794, PMID 22265362, PMID 22448928, PMID 22697193, PMID 23143523, PMID 23295604, PMID 23473656, PMID 25168927, PMID 28117049, PMID 28433500, PMID 34927594, PMID 36578677, PMID 37756123, PMID 37811711, PMID 39402517, PMID 40830714, PMID 41551193
2008 (1), R01HD111117 (1), R01MH062134 (1), R01MH080066 (1)