7 completed, 4 unknown, 2 active not recruiting, 2 enrolling by invitation. 14 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 6, Active not recruiting 2, Terminated 2, Unknown 2, Enrolling by invitation 1, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Lumbar Puncture: new trials by email Literature Review of Lumbar Puncture trials Research Report on Lumbar Puncture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS) ultrasound contrast - Lumbar Puncture | Not applicable | Recruiting | Vanderbilt University Medical Center | 80 | 2026-05-16 | 2026-05-29 |
| Ultrasound-assisted vs Palpation-guided Lumbar Punctures Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture - Lumbar Puncture | Not applicable | Enrolling by invitation | The Cooper Health System | 132 | 2026-04-25 | 2026-09-17 |
| Imran Technique for Spinal Anesthesia and Lumbar Puncture Conventional Sitting Position, Imran Technique - Spinal Anesthesia, Lumbar Puncture | Not applicable | Completed | Wah Medical college , POF hospital | 200 | 2026-03-02 | 2026-06-04 |
| Effect of Virtual Reality Distraction on Pain, Anxiety, Vital Signs in Patients Undergoing Lumbar Puncture distraction with virtual reality - Lumbar Puncture, Virtual Reality | Not applicable | Active not recruiting | Inonu University | 120 | 2025-04-01 | 2025-07-01 |
| Comparison of Lateral Decubitus and Upright Sitting Positions in Measuring Intervertebral Space Via Ultrasound in Obese Volunteers Spinal Column, Lumbar Puncture | Enrolling by invitation | Kocaeli City Hospital | 54 | 2025-04-01 | 2026-01-02 | |
| AI-Assisted Instruction Versus Peer Learning for Sustained Lumbar Puncture Competency Peer Learning - Lumbar Puncture | Not applicable | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 100 | 2025-01-01 | 2026-10-14 |
| SHAPE for ICP Assessment Perflutren lipid microsphere - Lumbar Puncture | Phase 2 | Completed | Thomas Jefferson University | 19 | 2024-12-15 | 2025-09-04 |
| Video-Assisted Informed Consent for Neonatal Lumbar Puncture Video assisted informed consent, Standard consent - Lumbar Puncture, Pediatrics | Not applicable | Active not recruiting | University of Texas at Austin | 100 | 2023-10-01 | 2025-07-20 |
| uSINE-PAMS Artificial Intelligence Driven, Ultrasound-Guided Lumbar Puncture to Improve Procedural Accuracy Intervention Arm (uSINE-PAMS-technique) - Ultrasound Therapy, Lumbar Puncture | Not applicable | Unknown | National Neuroscience Institute | 50 | 2023-05-26 | 2024-05-16 |
| Effect of Anodal Transcranial Direct Current Stimulation on Postdural Puncture Headache active in therapeutic tDCS (Th-tDCS): anodal transcranial Direct Current Stimulation (a-tDCS), sham in therapeutic tDCS (Th-tDCS): anodal transcranial Direct Current Stimulation (a-tDCS), active in preventive tDCS (Pr-tDCS): anodal transcranial Direct Current Stimulation (a-tDCS) - Postdural Puncture Headache, Lumbar Puncture | Not applicable | Completed | Neuromed IRCCS | 97 | 2022-01-11 | 2025-04-02 |
| Improvement of the Performance of Lumbar Punctures After Training Students With an Augmented Reality SIMulator performing lumbar punctures by students with standard training, training students augmented reality simulator - Lumbar Puncture | Not applicable | Completed | University Hospital, Strasbourg, France | 60 | 2021-12-02 | 2026-01-20 |
| The First Puncture Success Rate of a Novel Injeq IQ-Tip™ System in Pediatric Lumbar Punctures IQ-Tip(tm) system - Lumbar Puncture | Not applicable | Completed | Injeq Ltd | 50 | 2019-11-08 | 2023-06-13 |
| Ultrasound Guided Diagnostic Lumbar Puncture in Neurology Landmark-based lumbar puncture, Ultrasound-guided lumbar puncture - Lumbar Puncture | Not applicable | Terminated | Dartmouth-Hitchcock Medical Center | 38 | 2017-07-20 | 2024-01-31 |
| Acute Mental Stress During Lumbar Puncture Stress, Emotional, Spinal; Puncture, Complications, Headache | Unknown | Copenhagen University Hospital, Rigshospitalet | 50 | 2016-12-12 | 2017-06-20 | |
| Ultrasound Assisted Lumbar Puncture in the Neonate Palpation Landmark Technique, Ultrasound-Assisted Technique LP - Lumbar Puncture | Not applicable | Completed | Children's Hospital of Philadelphia | 91 | 2016-09-01 | 2026-07-13 |
| Impact of 50% Nitrous Oxide Inhalation on Pain and Anxiety Induced by Lumbar Puncture: a Double-blind Randomized Controlled Trial 50:50 mixture of nitrous oxide/oxygen - Lumbar Puncture | Phase 4 | Unknown | University Hospital, Clermont-Ferrand | 66 | 2014-07-01 | 2015-09-21 |
| Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children J-Tip, EMLA, Lidocaine - Lumbar Puncture, Topical Analgesia | Not applicable | Terminated | University of Colorado, Denver | 66 | 2012-09-01 | 2019-06-21 |
| Pediatric Lumbar Puncture Success Using the COMPASS Compass Lumbar Puncture Enhanced - Lumbar Puncture | Not applicable | Unknown | Seattle Children's Hospital | 60 | 2011-01-01 | 2011-02-17 |
Headache (2) · Post-Dural Puncture Headache (2) · Anxiety Disorders (1) · Fever (1) · Meningitis (1) · Pain (1) · Pain, Procedural (1) · Sepsis (1) · Stress, Psychological (1)
Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Neurologic Manifestations (4) · Nervous System Diseases (3) · Pain (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Headache Disorders (2) · Headache Disorders, Secondary (2) · Behavior (1) · Behavioral Symptoms (1) · Body Temperature Changes (1) · Infections (1) · Inflammation (1) · Mental Disorders (1)
Drug Delivery Systems (1) · Lidocaine (1) · Lidocaine, Prilocaine Drug Combination (1) · Oxygen (1) · perflutren (1)
Children's Hospital of Philadelphia (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dartmouth-Hitchcock Medical Center (1) · Injeq Ltd (1) · Inonu University (1) · Kocaeli City Hospital (1) · National Neuroscience Institute (1) · Neuromed IRCCS (1) · Seattle Children's Hospital (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · The Cooper Health System (1) · Thomas Jefferson University (1) · University Hospital, Clermont-Ferrand (1) · University Hospital, Strasbourg, France (1) · University of Colorado, Denver (1)
United States (8) · France (2) · Turkey (Türkiye) (2) · China (1) · Denmark (1) · Finland (1) · Italy (1) · Pakistan (1) · Singapore (1)
Imran Ul Haq, MBBS, FCPS (1) · JUlie C. Brown, MD, MPH (1) · Jason Stoller, MD (1) · Kathleen Adelgais, MD, MPH (1) · Lars Konge, MD, PhD (1) · Matthew Wilkinson, MD, MPH (1) · Ryan Caltagirone, MD (1) · Sauli Palmu, PhD MD (1)
PMID 29160002, PMID 40201070, PMID 40261600, PMID 40885925, PMID 42103066
2014 (1)