4 completed, 3 recruiting, 2 unknown, 1 active not recruiting. 6 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Unknown 2, Recruiting 1, Withdrawn 1 |
| Phase 1 | 1 | Suspended 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Lumbar Disc Degeneration: new trials by email Literature Review of Lumbar Disc Degeneration trials Research Report on Lumbar Disc Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SCLife®-LDD hUC-MSCs Injection Therapy for Patients With Lumbar Intervertebral Disc Degeneration human umbilical cord mesenchymal stem cell suspension, total endoscopic extraction of lumbar nucleus pulposus - Lumbar Disc Degeneration | Phase 1 | Suspended | Sclnow Biotechnology Co., Ltd. | 20 | 2026-12-31 | 2026-04-27 |
| Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery Opioid-free Anesthesia, Erector Spinae Plane Block, Opioid based Anesthesia - Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy | Recruiting | Marmara University | 75 | 2025-12-09 | 2026-03-23 | |
| The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease Lumbar Disc Herniation, Lumbar Disc Degeneration | Recruiting | Masaryk University | 400 | 2025-06-01 | 2025-08-27 | |
| Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain Midline Lumbar Interbody Fusion (MIDLIF), Minimally Invasive Transforaminal Lumbar Interbody Fusion (mini-TLIF) - Lower Back Pain Chronic, Lumbar Degenerative Disease | Not applicable | Recruiting | Copernicus Memorial Hospital | 100 | 2025-01-19 | 2026-04-15 |
| Application of Internet Plus Nursing Intervention in Postoperative Rehabilitation of Patients With Lumbar Disc Herniation Internet plus applet - Lumbar Disc Degeneration | Not applicable | Completed | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 100 | 2024-02-20 | 2026-04-23 |
| Intervertebral DXM Gel Injection in Adults With Painful Lumbar Degenerative Disc Disease Double Crosslink Microgel - Degenerative Disc Disease, Chronic Lower Back Pain | Not applicable | Unknown | Gelmetix | 20 | 2020-09-15 | 2021-01-27 |
| Human Umbilical Cord Mesenchymal Stem Cells For the Treatment of Lumbar Disc Degeneration Disease human umbilical cord mesenchymal stem cells - Lumbar Disc Degeneration, Lumbar Disc Herniation | Not applicable | Unknown | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 20 | 2020-08-01 | 2020-06-04 |
| Interleukin-1β (rs 1143627 T/C) Gene Polymorphism May Increase the Risk of Developing LDD in Turkish Population Lumbar Disc Degeneration, Low Back Pain | Completed | Yeditepe University | 94 | 2019-04-08 | 2022-11-01 | |
| Evidence For Fusion In Spine With Orthoss® Orthoss - Lumbar Spondylolisthesis Involving L4-L5, Lumbar Spondylolisthesis Involving L5-S1 | Active not recruiting | Geistlich Pharma AG | 65 | 2019-01-18 | 2026-09-11 | |
| A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Exparel, Bupivacaine - Low Back Pain, Lumbosacral Radiculopathy | Phase 4 | Terminated | Virtua Health, Inc. | 19 | 2016-12-01 | 2021-01-06 |
| Evaluation of Topical and Intravenous Tranexamic Acid in Surgical Treatment of Lumbar Degenerative Disease Observational - Lumbar Disc Degeneration, Surgical Procedure, Unspecified | Not applicable | Withdrawn | Vinicius Magno da Rocha, MD, MSc | 2014-03-01 | 2021-09-02 | |
| A Zhineng Qigong Intervention for Patients With Chronic Low Back Pain and/or Leg Pain Zhineng Qigong intervention - Chronic Low Back Pain, Chronic Sciatica | Not applicable | Completed | Lund University | 55 | 2013-11-01 | 2020-08-20 |
| Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement Total lumbar disc prosthesis (Baguera®L, Spineart, Switzerland) - Lumbar Disc Degeneration, Lumbar Disc Disease | Completed | University of Valencia | 130 | 2008-01-01 | 2026-06-17 |
Intervertebral Disc Degeneration (13) · Intervertebral Disc Displacement (5) · Low Back Pain (5) · Spinal Stenosis (3) · Intervertebral disc disease (2) · Spondylolisthesis (2) · Constriction, Pathologic (1) · Inflammation (1) · Motor Activity (1) · Pain, Postoperative (1) · Sciatica (1) · Spondylolysis (1)
Bone Diseases (13) · Musculoskeletal Diseases (13) · Spinal Diseases (13) · Pathological Conditions, Signs and Symptoms (8) · Neurologic Manifestations (7) · Pain (7) · Signs and Symptoms (7) · Back Pain (5) · Hernia (5) · Pathological Conditions, Anatomical (5) · Pathologic Processes (2) · Spondylosis (2) · Behavior (1) · Mononeuropathies (1) · Nervous System Diseases (1)
Bupivacaine (1) · Watchful Waiting (1)
Copernicus Memorial Hospital (1) · Geistlich Pharma AG (1) · Gelmetix (1) · Lund University (1) · Marmara University (1) · Masaryk University (1) · Sclnow Biotechnology Co., Ltd. (1) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (1) · The Fourth Affiliated Hospital of Zhejiang University School of Medicine (1) · University of Valencia (1) · Vinicius Magno da Rocha, MD, MSc (1) · Virtua Health, Inc. (1) · Yeditepe University (1)
China (3) · Turkey (Türkiye) (2) · Czechia (1) · France (1) · Germany (1) · Poland (1) · Spain (1) · Sweden (1) · United States (1)
Fabiana Martinelli (1) · Gabriella Pozarek, MD (1) · Qiang Fu, M.D. (1) · Robert Greenleaf, MD (1)