33 completed, 8 unknown, 4 recruiting, 3 terminated. 49 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 49 | Completed 33, Unknown 8, Recruiting 4, Terminated 3, Withdrawn 1 |
Follow Liver Transplantation: new trials by email Literature Review of Liver Transplantation trials Research Report on Liver Transplantation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HOPE Against Cancer Recurrence in HCC Hypothermic oxygenated perfusion, Conventional cold storage - Liver Transplantation, HCC | Phase 4 | Recruiting | Philipp Dutkowski | 220 | 2025-08-01 | 2025-12-16 |
| Reducing Pain With Methadone and Ketamine in Liver Transplant Methadone, ketamine, Hydromorphone - Liver Transplantation | Phase 4 | Completed | Lahey Clinic | 50 | 2025-06-30 | 2026-08-11 |
| Evaluation of the Benefits of Administering Immunosuppressive Drugs as Single Daily Doses Over the First Year After Liver Transplantation (EASY) XR-tacrolimus QD + MMF BID then MMF QD, XR-tacrolimus QD + MMF BID, LCP-tacrolimus QD + MMF QD then MMF QD - Liver Transplantation, Immunosuppression | Phase 4 | Recruiting | University Hospital, Limoges | 162 | 2025-04-15 | 2026-03-19 |
| Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation Albumin administration - Liver Transplantation, Acute Kidney Injury | Phase 4 | Recruiting | Rennes University Hospital | 400 | 2025-03-26 | 2026-06-17 |
| Early Conversion of Prolonged-release Tacrolimus in Liver Transplantation. Tacrolimus Sustained-release Capsules - Liver Transplantation | Phase 4 | Unknown | Beijing Tsinghua Chang Gung Hospital | 352 | 2023-12-01 | 2023-11-27 |
| Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulations Tacrolimus, Immediate Release, Oral, Tacrolimus Extended Release Oral Tablet - Liver Transplantation, Immunosuppression | Phase 4 | Recruiting | University of British Columbia | 124 | 2023-01-09 | 2024-01-02 |
| To Evaluate the Efficacy and Safety of Micafungin in Preventing Invasive Mycosis After Liver Transplantation Micafungin Sodium 50 MG Injection, Caspofungin Acetate - Liver Transplantation | Phase 4 | Unknown | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 200 | 2022-10-01 | 2022-08-16 |
| A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients Tacrolimus granules - Liver Transplantation, Kidney Transplantation | Phase 4 | Completed | Astellas Pharma China, Inc. | 55 | 2022-01-11 | 2025-03-17 |
| A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients Tacrolimus granules - Liver Transplantation, Kidney Transplantation | Phase 4 | Completed | Astellas Pharma China, Inc. | 56 | 2021-12-30 | 2025-03-17 |
| Treatment of Anemia With Intravenous Iron in Patients Listed for Orthotopic Liver Transplantation Iron Carboxymaltose, Placebo - Liver Transplantation, Blood Loss | Phase 4 | Unknown | Medical University of Vienna | 60 | 2020-07-23 | 2020-07-28 |
| A Study to Compare the Finger Prick Whole Blood MITRA Assay Method With the Established Venepuncture Whole Blood Method for Quantitative Determination of Tacrolimus Blood Concentrations in Transplant Patients tacrolimus - Kidney Transplantation, Liver Transplantation | Phase 4 | Completed | Astellas Pharma Europe Ltd. | 80 | 2018-03-20 | 2018-10-15 |
| A Study of Patient Adherence and Convenience to Immunosuppressive Agents in Newly Liver Transplant Advagraf, Prograf - Liver Transplantation | Phase 4 | Unknown | Chang Gung Memorial Hospital | 150 | 2017-11-23 | 2020-06-05 |
| Insulin Therapy for Postreperfusion Hyperglycemia Insulin - Hyperglycaemia (Diabetic), Liver Transplantation | Phase 4 | Unknown | Seoul National University Hospital | 20 | 2017-05-15 | 2024-04-19 |
| To Evaluate the Efficacy and Safety of ADVAGRAF® After Treatment With a Tacrolimus in New Liver Transplant Recipients ADVAGRAF® - Liver Transplantation | Phase 4 | Completed | Kim, Seoung-Hoon | 31 | 2016-03-22 | 2018-02-06 |
| Twice-daily Tacrolimus and Everolimus Convert to Once-daily Tacrolimus and Everolimus in Liver Transplant Recipient Tacrolimus and Everolimus - Liver Transplantation | Phase 4 | Completed | Chang Gung Memorial Hospital | 10 | 2016-01-01 | 2020-06-05 |
| To Evaluate the Efficacy and Safety of ADVAGRAF® After Treatment With a Tacrolimus in New Liver Transplant Recipients ADVAGRAF® - Liver Transplantation | Phase 4 | Completed | Linical Korea | 31 | 2015-07-01 | 2021-02-21 |
| Entecavir Combined Short-term Intravenous Hepatitis B Immune Globulin (HBIG) to Prevent Hepatitis B Recurrence After Liver Transplantation Entecavir combined long-term low-dose HBIG group intramuscular, Entecavir combined HBIG group short-term high-dose intravenous - Hepatitis B, Liver Transplantation | Phase 4 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 60 | 2015-04-01 | 2015-04-15 |
| Efficacy of Low-dose Dexmedetomidine to Prevent Delirium in Liver Transplant Patients Precedex, placebo control - Liver Transplantation | Phase 4 | Completed | Seoul National University Hospital | 217 | 2014-09-01 | 2019-09-25 |
| Early Treatment of Recurrent HCV- Infection Post Liver Transplantation in the Era of DAAs treatment of HCV with oral direct acting antiviral therapy - Liver Transplantation | Phase 4 | Completed | Ain Shams University | 89 | 2014-09-01 | 2017-04-28 |
| Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney Terlipressin, placebo - Acute Kidney Injury, Liver Transplantation | Phase 4 | Completed | National Liver Institute, Egypt | 25 | 2013-05-01 | 2016-12-15 |
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Acute Kidney Injury (2) · Hepatitis B (2) · Hepatitis C (2) · Acute Pain (1) · Anemia (1) · Carcinoma, Hepatocellular (1) · Delirium (1) · Fractures, Bone (1) · Hemorrhage (1) · Hyperglycemia (1) · Insulin Resistance (1) · Invasive Fungal Infections (1) · Latent Tuberculosis (1) · Liver Diseases (1) · Neurotoxicity Syndromes (1)
Digestive System Diseases (6) · Infections (6) · Liver Diseases (5) · Blood-Borne Infections (4) · Communicable Diseases (4) · Hepatitis (4) · Hepatitis, Viral, Human (4) · Pathological Conditions, Signs and Symptoms (4) · Virus Diseases (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Kidney Diseases (3) · Male Urogenital Diseases (3) · Neurologic Manifestations (3) · Signs and Symptoms (3)
Tacrolimus (20) · Mycophenolic Acid (8) · Cyclosporine (3) · Adrenal Cortex Hormones (2) · Antilymphocyte Serum (2) · Basiliximab (2) · Everolimus (2) · Prednisone (2) · Saline Solution (2) · 13-valent pneumococcal vaccine (1) · Caspofungin (1) · Desflurane (1) · Dexmedetomidine (1) · Fentanyl (1) · Hydromorphone (1)
Seoul National University Hospital (4) · Astellas Pharma Europe Ltd. (3) · Astellas Pharma Inc (3) · Hoffmann-La Roche (3) · Novartis Pharmaceuticals (3) · Astellas Pharma China, Inc. (2) · Chang Gung Memorial Hospital (2) · Novartis (2) · The University of Texas Health Science Center, Houston (2) · University Health Network, Toronto (2) · University Hospital, Limoges (2) · Ain Shams University (1) · Beijing Tsinghua Chang Gung Hospital (1) · Cangene Corporation (1) · Children's Memorial Health Institute, Poland (1)
France (11) · United States (10) · Canada (6) · Germany (6) · South Korea (6) · United Kingdom (5) · Belgium (4) · China (4) · Poland (4) · Spain (4) · Switzerland (3) · Taiwan (3) · Austria (2) · Italy (2) · Australia (1)
Bob Saggi, MD (1) · Calmus Yvon, PhD (1) · Chul-Woo Jung, MD, PhD (1) · David M Baron, MD (1) · Deepali Kumar, MD (1) · Fady M Kaldas, MD (1) · Geoffrey McCaughan, PhD, MB BS (1) · Georg P Gyoeri, MD (1)
PMID 16490909, PMID 25873064, PMID 26335917, PMID 28564127, PMID 30098071, PMID 30665258, PMID 34525259, PMID 41013675
2009 (3), 2017 (1)