59 completed, 16 unknown, 15 terminated, 3 active not recruiting. 35 Phase 2, 29 Phase 4, 25 Phase 3, 8 Phase 1, 4 Not applicable.
Follow Basiliximab: new trials by email Literature Review of Basiliximab trials Research Report on Basiliximab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 1 vs 7 RATG Infusions in Renal Transplantation RATG, Basiliximab - Kidney Replacement | Active not recruiting | Mario Negri Institute for Pharmacological Research | 75 | 2024-07-30 | 2025-09-04 | |
| Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases Basiliximab - Acute Graft Versus Host Disease, Malignant Hematologic Neoplasm | Phase 2 | Not yet recruiting | Anhui Provincial Hospital | 39 | 2024-07-01 | 2024-06-28 |
| Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies Rabbit Anti thymocyte globulin (rATG), Basiliximab - Renal Transplant Rejection, Induction Therapy | Phase 3 | Recruiting | University Hospital, Tours | 244 | 2023-11-07 | 2026-06-18 |
| Vedolizumab, Anti-CD25 Antibody, Rapid Reduction of Glucocorticoids for SR-aGVHD With Gastrointestinal Involvement Basiliximab, Vedolizumab - Safety and Efficacy | Phase 4 | Unknown | The First Affiliated Hospital of Soochow University | 45 | 2022-08-01 | 2023-10-04 |
| 90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome Allogeneic Hematopoietic Stem Cell Transplantation, Basiliximab, Fludarabine Phosphate - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 1 | Active not recruiting | City of Hope Medical Center | 7 | 2022-07-19 | 2026-07-06 |
| Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR Twice-daily Tacrolimus, Once-daily envarsus XR, Induction Immunosuppression with Basiliximab or Rabbit Anti Thymoglobulin (rATG) - Kidney Transplantation, Kidney Transplant Rejection | Phase 4 | Terminated | University of Southern California | 20 | 2021-11-23 | 2025-11-10 |
| Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma Basiliximab, Carmustine, Cytarabine - Recurrent Hodgkin Lymphoma, Refractory Hodgkin Lymphoma | Phase 2 | Recruiting | City of Hope Medical Center | 33 | 2021-11-02 | 2025-12-04 |
| Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients Basiliximab Injection, Placebo - SARS-CoV-2 Acute Respiratory Disease, SARS-CoV2 Infection | Phase 2 | Unknown | Fort Worth Clinical Sciences Working Group | 300 | 2021-10-15 | 2021-08-19 |
| Impact of the Microbiota on the Likelihood of Renal Graft Rejection Belatacept Injection [Nulojix] - Kidney Transplant Rejection | Active not recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 70 | 2021-10-07 | 2026-08-03 | |
| Efficacy and Safety of UC-MSCs for the Treatment of Steroid-resistant aGVHD Following Allo-HSCT UC-MSC, Anti-CD25 mAb - Graft Vs Host Disease | Phase 3 | Completed | Peking University People's Hospital | 130 | 2021-02-01 | 2023-06-01 |
| Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant Basiliximab 20 MG - Asses Immunosuppression Modulation on Renal Recovery Post LT | Phase 4 | Completed | Fady M Kaldas, M.D., F.A.C.S. | 71 | 2021-01-15 | 2025-12-16 |
| Basiliximab Combined With Ruxolitinib as Second-line Treatment of Grade 3-4 Steroid-resistant aGVHD Ruxolitinib - Safety and Efficacy | Phase 4 | Unknown | The First Affiliated Hospital of Soochow University | 50 | 2020-12-15 | 2021-08-25 |
| Standard Induction With Basiliximab Versus No-Induction in Low Immunological Risk Kidney Transplant Recipients Basiliximab 20 milligram [Simulect], Normal Saline - Kidney Transplantation | Phase 4 | Unknown | King Faisal Specialist Hospital & Research Center | 140 | 2020-09-01 | 2021-02-18 |
| Combination of Basiliximab and Pegaspargase in the Treatment of ENKTCL Basiliximab, Pegaspargase - Extranodal NK/T-cell Lymphoma | Phase 2 | Unknown | Beijing Tongren Hospital | 20 | 2020-06-01 | 2020-04-07 |
| Impact of Lymphocyte Anti-metabolite Immunosuppressions on Donor-Specific Anti-HLA Antibody and Kidney Graft Outcome Mycophenolate mofetil 500mg Tab. or 250mg Cap., Tacrolimus, Methylprednisolone/prednisolone - Kidney Transplant | Phase 4 | Completed | Chong Kun Dang Pharmaceutical | 169 | 2018-03-31 | 2024-05-22 |
| Antithymocyte Globulin and Azathioprine Versus Basiliximab and Mycophenolate Mofetil in Living Donor Kidney Transplantation Antithymocyte Immunoglobulin (Rabbit), Interleukin 2 Receptor Antagonist - Kidney Transplant Rejection | Phase 4 | Unknown | University of Khartoum | 300 | 2018-03-21 | 2019-01-03 |
| Basiliximab Treating Interstitial Pneumonia of CADM Basiliximab, Calcineurin Inhibitors, Steroids - Lung; Disease, Interstitial, With Fibrosis, Dermatomyositis | Phase 2 | Unknown | RenJi Hospital | 100 | 2017-07-01 | 2017-06-20 |
| Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients Bleselumab, Basiliximab, Mycophenolate Mofetil (MMF) - Kidney Transplantation, Primary Focal Segmental Glomerulosclerosis (FSGS) | Phase 2 | Completed | Astellas Pharma Global Development, Inc. | 67 | 2017-05-22 | 2024-12-04 |
| Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major Busulfan, Cyclophosphamide, Fludarabine - Thalassemia Major | Phase 4 | Unknown | First Affiliated Hospital of Guangxi Medical University | 30 | 2017-04-01 | 2017-05-31 |
| Multicenter Trial of the Effect of AAT on Islet Transplant Engraftment and Durability After Renal Transplant Alpha 1-Antitrypsin, Islet Transplantation, Thymoglobulin - Kidney Transplant, Type 1 Diabetes | Phase 2 | Completed | Massachusetts General Hospital | 2 | 2017-01-01 | 2023-12-22 |
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Diabetes Mellitus, Type 1 (10) · Graft vs Host Disease (5) · Hypoglycemia (5) · Rejection, Psychology (5) · Hodgkin Disease (4) · Kidney Failure, Chronic (4) · Renal Insufficiency (4) · Leukemia, Myeloid, Acute (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Anemia, Refractory, with Excess of Blasts (2) · Colitis, Ulcerative (2) · Glioblastoma (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2) · Lymphoma, Non-Hodgkin (2)
National Institute of Allergy and Infectious Diseases (NIAID) (11) · Novartis Pharmaceuticals (11) · Novartis (9) · Astellas Pharma Inc (6) · Cerimon Pharmaceuticals (3) · City of Hope Medical Center (3) · Astellas Pharma Global Development, Inc. (2) · Indiana University (2) · Mario Negri Institute for Pharmacological Research (2) · The First Affiliated Hospital of Soochow University (2) · University Hospital Freiburg (2) · University of Chicago (2) · University of Oxford (2) · Anhui Provincial Hospital (1) · Armando Torres Ramírez (1)
United States (38) · France (14) · Germany (14) · China (11) · Canada (9) · Switzerland (9) · Italy (7) · Spain (7) · United Kingdom (7) · Belgium (6) · Sweden (6) · Austria (5) · Czechia (5) · Mexico (5) · Norway (5)
Andrew Posselt, MD, PhD (2) · Bernhard Hering, MD (2) · Camillo Ricordi, MD (2) · Fady M Kaldas, MD (2) · Giuseppe Remuzzi, MD (2) · Kenneth Newell, MD, PhD (2) · Nicole Turgeon, MD (2) · Olle Korsgren, MD (2) · Robert Nelson, MD (2)
PMID 39382091, PMID 17093248, PMID 23438305, PMID 16273116, PMID 16699456, PMID 16737942, PMID 18322043, PMID 18416737, PMID 19005405, PMID 19005406, PMID 19663893, PMID 20380712, PMID 20840760, PMID 20930086, PMID 21768296, PMID 22471345, PMID 22549092, PMID 22850297, PMID 23230975, PMID 23422495, PMID 23630300, PMID 23641902, PMID 23738760, PMID 23866828, PMID 25041339, PMID 25078310, PMID 25629445, PMID 26018348, PMID 26285695, PMID 26313245, PMID 26369526, PMID 26888217, PMID 27208344, PMID 27465220, PMID 27547871, PMID 27871759, PMID 28556519, PMID 28605781, PMID 29149958, PMID 29226570, PMID 29308669, PMID 29344432, PMID 29563196, PMID 29752413, PMID 29779835, PMID 29963053, PMID 30211831, PMID 30231851, PMID 30582281, PMID 30903722
2008 (4), 2009 (4), P30CA033572 (2), 2005 (1), P01CA030206 (1), P30CA014236 (1), P50CA107399 (1), P50CA108786 (1), R21CA185875 (1)