84 completed, 41 unknown, 26 recruiting, 15 not yet recruiting. 52 Not applicable, 21 Phase 3, 18 Phase 4, 17 Phase 2, 14 Phase 1.
Follow Latent Tuberculosis: new trials by email Literature Review of Latent Tuberculosis trials Research Report on Latent Tuberculosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shaping a Community-based Pathway to Improve TB Surveillance Among African and Hindustan Immigrants Experiencing Vulnerabilities Tuberculosis, Tuberculosis (TB) | Not yet recruiting | Universidade Nova de Lisboa | 200 | 2026-12-01 | 2026-07-07 | |
| Integrating Tuberculosis Treatment Into Community Pharmacies to Improve TB/HIV Outcomes in Uganda The intervention is TB treatment delivery via community pharmacies for people with TB/HIV, Control Arm - standard of care - TB - Tuberculosis, HIV - Human Immunodeficiency Virus | Not applicable | Not yet recruiting | Makerere University | 124 | 2026-10-01 | 2026-09-25 |
| A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV Rifapentine, Isoniazid, Dolutegravir - Tuberculosis | Phase 1 / Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 144 | 2026-09-28 | 2026-10-19 |
| Screening With Portable X-rays for Rapid Recognition of TB Mobile chest radiography for tuberculosis screening - Tuberculosis (TB), Tuberculosis Infection, Latent | Not applicable | Recruiting | Columbia University | 1000 | 2026-08-25 | 2026-10-02 |
| Incidence of Tuberculosis in Patients With Autoimmune Rheumatic Diseases re-screening, No Rescreening - Autoimmune Rheumatic Diseases, Prevention | Not applicable | Not yet recruiting | University of Sao Paulo General Hospital | 1660 | 2026-08-01 | 2026-08-18 |
| BPaLMZ for TB Meningitis BPaLMZ Regimen - Tuberculous Meningitis, HIV | Phase 2 | Recruiting | David Boulware | 312 | 2026-07-28 | 2026-10-16 |
| COPD-PTB Screening Trial in Henan, China ACF strategy - Chronic Obstructive Pulmonary Disease (COPD), TB - Tuberculosis | Not applicable | Not yet recruiting | Henan Provincial People's Hospital | 25000 | 2026-07-20 | 2026-07-16 |
| Rifapentine-Based Shorter Regimens for Tuberculosis and TB Infection in Kazakhstan Tuberculosis, Tuberculosis Infection, Latent | Not yet recruiting | Public Union "Kazakhstan Association of Phthisiopulmonologists" | 350 | 2026-07-01 | 2026-06-25 | |
| SCAF-TB - Saving Children and Their Families From Tuberculosis: Implementation Research to Improve TB Preventive Treatment Initiation and Completion Rates Among Contact Persons in Tajikistan and Tanzania CY-TB Patch, Audiblehealth DX - Tuberculosis Infection, Latent, Tuberculosis Active | Not applicable | Not yet recruiting | KNCV Tuberculosis Foundation | 880 | 2026-06-01 | 2026-07-20 |
| Comparative Trial Between Ainuovirine(ANV)/Lamivudine(3TC)/Tenofovir(TDF) and Efavirenz(EFV)/Lamivudine/Tenofovir Regimens Ainuovirine, Lamivudine and Tenofovir Disoproxil Fumarate Tablets, Tenofovir, Lamivudine and Efavirenz Disoproxil Fumarate Tablets - HIV, Art Therapy | Phase 4 | Not yet recruiting | Shanghai Public Health Clinical Center | 60 | 2026-06-01 | 2026-06-08 |
| Isoniazid-Related Hepatotoxicity in Clinical Practice: Incidence and Predictors Standard isoniazid-based TB/LTBI therapy - Tuberculosis Infection, Tuberculosis Infection, Latent | Not yet recruiting | ASST Fatebenefratelli Sacco | 220 | 2026-05-30 | 2026-03-16 | |
| Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TB Bedaquiline, Isoniazid, rifapentine, Levofloxacin - Tuberculosis, Latent | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 2530 | 2026-05-08 | 2026-10-20 |
| Start4All SCREEN-TB PROTOCOL Near point of care (NPOC) NAATs, Low-complexity nucleic acid amplification tests (LC-NAATs), LC-NAAT using pooled testing - TB - Tuberculosis | Not applicable | Not yet recruiting | Liverpool School of Tropical Medicine | 37000 | 2026-04-01 | 2026-04-08 |
| Pharmacokinetics of Antituberculosis Drugs in Breastfeeding Women Standard dose rifampicin, High dose rifampicin, Standard dose isoniazid - Tuberculosis Infection, Healthy Volunteer | Phase 1 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 60 | 2026-04-01 | 2026-02-10 |
| Parent Study Name: Pulmonary Rehabilitation to Reduce Post-Tuberculosis Morbidity (TB Pure) 8 week (short arm) Intervention - pulmonary rehabilitation, 24 week (long arm) Intervention - pulmonary rehabilitation - TB - Tuberculosis, TB | Not applicable | Recruiting | Johns Hopkins University | 690 | 2026-03-18 | 2026-03-27 |
| Start Taking Action for Tuberculosis in Kids Xpert MTB/RIF Ultra, Truenat, MTB, Truenat MTB Plus - TB - Tuberculosis | Not applicable | Not yet recruiting | Liverpool School of Tropical Medicine | 7920 | 2026-03-01 | 2025-11-25 |
| Start4All - Start Taking Action for TB Diagnosis (DARE-TB) Near point of care (NPOC) NAATs, Low-complexity nucleic acid amplification tests (LC-NAATs), LC-NAAT using pooled testing - TB - Tuberculosis | Not applicable | Not yet recruiting | Liverpool School of Tropical Medicine | 60000 | 2026-03-01 | 2026-02-19 |
| Burden of Tuberculosis Among Pregnant and Postpartum Women in Guinea-Bissau Enhanced protocol - Tuberculosis (TB), Tuberculosis Infection, Latent | Not applicable | Not yet recruiting | Aarhus University Hospital | 720 | 2026-02-01 | 2026-02-19 |
| Prevalence of Latent Tuberculosis Infection Among Hemodialysis Patients Tuberculin Skin Test (TST) - Latent Tuberculosis Infection, End Stage Renal Disease (ESRD) | Not yet recruiting | Sohag University | 200 | 2025-12-01 | 2025-10-07 | |
| Window Prophylaxis for Pediatric Tuberculosis Prevention Trial Tuberculosis window prophylaxis with weekly rifapentine and isoniazid for 12 weeks, Standard of care tuberculosis prophylaxis with weekly rifapentine and isoniazid for 12 weeks - Tuberculosis Infection, Household Contacts | Not applicable | Recruiting | Pontificia Universidad Catolica de Chile | 647 | 2025-10-27 | 2025-12-29 |
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Tuberculosis (91) · Tuberculosis, Pulmonary (12) · Acquired Immunodeficiency Syndrome (11) · HIV Infections (10) · Mycobacterium Infections (6) · Diabetes Mellitus (5) · Tuberculosis, Multidrug-Resistant (5) · Kidney Failure, Chronic (4) · Communicable Diseases (3) · Infections (3) · Pulmonary Disease, Chronic Obstructive (3) · Virus Diseases (3) · Bacterial Infections (2) · COVID-19 (2)
Actinomycetales Infections (198) · Bacterial Infections and Mycoses (198) · Gram-Positive Bacterial Infections (198) · Latent Infection (197) · Bacterial Infections (196) · Infections (195) · Mycobacterium Infections (192) · Tuberculosis (107) · Urogenital Diseases (30) · Immune System Diseases (23) · Genital Diseases (22) · Blood-Borne Infections (21) · Immunologic Deficiency Syndromes (21) · Lentivirus Infections (21) · Pathological Conditions, Signs and Symptoms (21)
Isoniazid (32) · rifapentine (19) · Rifampin (14) · Tuberculin (7) · Blood Specimen Collection (4) · Levofloxacin (4) · Diagnostic Imaging (3) · Vitamin B 6 (3) · X-Rays (3) · bedaquiline (3) · Chemoprevention (2) · Cholecalciferol (2) · Diagnosis, Computer-Assisted (2) · Ethambutol (2) · Injections (2)
National Taiwan University Hospital (8) · Johns Hopkins University (6) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · Centers for Disease Control and Prevention (5) · Queen Mary University of London (5) · Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. (4) · Instituto Nacional de Salud Publica, Mexico (4) · McGill University Health Centre/Research Institute of the McGill University Health Centre (4) · Aeras (3) · Chinese University of Hong Kong (3) · Fundació Institut Germans Trias i Pujol (3) · Germans Trias i Pujol Hospital (3) · Hanyang University (3) · Huashan Hospital (3) · Liverpool School of Tropical Medicine (3)
United States (27) · South Africa (20) · United Kingdom (13) · China (12) · South Korea (12) · Spain (11) · Canada (10) · Taiwan (10) · Uganda (10) · Vietnam (9) · Brazil (8) · France (8) · Indonesia (8) · Italy (8) · India (7)
Dick Menzies, MD (5) · Chin-Chung Shu, MD (3) · Cristina Vilaplana, MD, PhD (3) · Pere-Joan Cardona, MD, PhD (3) · Angelique Luabeya, MD (2) · Dereck Tait, MD (2) · Dick Menzies (2) · Grant Theron, PhD (2) · Heiman F Wertheim, PhD (2) · Holly Rawizza, MD, MPH (2) · Martina Sester, PhD (2) · Maunank Shah, MD, PhD (2) · Robert Belknap, MD (2) · Thomas B Nutman, M.D. (2) · Wenhong Zhang, PhD (2)
PMID 25359354, PMID 31866327, PMID 32539440, PMID 32785709, PMID 36730240, PMID 36949623, PMID 17463418, PMID 17504682, PMID 18419884, PMID 19383198, PMID 19656705, PMID 19880906, PMID 20627913, PMID 21765072, PMID 22150035, PMID 22161161, PMID 22923457, PMID 22936710, PMID 23694948, PMID 24454900, PMID 24586912, PMID 24719431, PMID 24788998, PMID 24835842, PMID 25265362, PMID 25303140, PMID 25404412, PMID 25904367, PMID 26213798, PMID 26260821, PMID 26761521, PMID 27010173, PMID 27223167, PMID 27243774, PMID 27268103, PMID 27862893, PMID 28043488, PMID 28406884, PMID 28960029, PMID 29020191, PMID 29114781, PMID 29393655, PMID 29437940, PMID 29661197, PMID 29726024, PMID 29764958, PMID 29978556, PMID 29982223, PMID 30029896, PMID 30067928
2009 (1), K43TW012839 (1), R01AI095041 (1), R01AI162888 (1), R01AI169588 (1), R01HL144406 (1), R01NR020866 (1), R21AI172182 (1), R21AI191193 (1), R21MD012696 (1), R61HL146365 (1), U54GM115677 (1)