32 completed. 32 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 32 | Completed 32 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow Lichen Planus: new trials by email Literature Review of Lichen Planus trials Research Report on Lichen Planus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study Baricitinib 4 milligram Oral Tablet - Lichen Planus, Oral, Lichen Planus, Mucosal | Phase 2 | Completed | University of North Carolina, Chapel Hill | 10 | 2024-03-13 | 2026-10-30 |
| A Study of Deucravacitinib to Treat LPP and FFA Deucravacitinib - Lichen Planopilaris | Phase 2 | Completed | Mayo Clinic | 12 | 2023-11-07 | 2025-06-08 |
| A Comparison of Photodynamic Therapy and Topical Clobetasol in Treatment of Oral Lichen Planus: a Split-Mouth Randomised Controlled Study Photodynamic Therapy, Clobetasol - Oral Lichen Planus | Phase 2 | Completed | Wroclaw Medical University | 29 | 2023-06-01 | 2024-12-30 |
| Evaluation of Efficacy of Neem (Azadirachta Indica) Versus Triamcinolone Acetonide in the Treatment of Oral Lichen Planus. Neem gel, Triamcinolone Acetonide - Oral Lichen Planus | Phase 1 / Phase 2 | Completed | Goa Dental College | 60 | 2023-02-05 | 2025-09-03 |
| Ritlecitinib for Cicatricial Alopecia PF-06651600 - Cicatricial Alopecia | Phase 2 | Completed | Emma Guttman | 50 | 2022-12-15 | 2026-07-15 |
| A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen Planus Ruxolitinib cream, Vehicle cream - Cutaneous Lichen Planus | Phase 2 | Completed | Incyte Corporation | 64 | 2022-11-23 | 2024-10-24 |
| Baricitinib (LY3009104) in the Treatment of Cutaneous Lichen Planus Baricitinib (LY3009104) 2 mg, Baricitinib (LY3009104) 4 mg - Cutaneous Lichen Planus | Phase 2 | Completed | Aaron R. Mangold | 12 | 2022-01-11 | 2024-06-11 |
| Dexamethasone Solution and Dexamethasone in Mucolox™ dexamethasone 0.5mg/5ml solution, dexamethasone 0.5mg/5ml solution in Mucolox™ - Oral Lichen Planus, Mucous Membrane Pemphigoid | Phase 2 | Completed | University of California, San Francisco | 29 | 2020-12-26 | 2023-12-15 |
| Comparison of Clinical Efficiency of Photodynamic Therapy and Topical Corticosteroid in Treatment of Oral Lichen Planus Triamcinolone Acetonide, Photodynamic Therapy - Lichen Planus, Oral | Phase 2 | Completed | Wroclaw Medical University | 30 | 2020-12-10 | 2021-08-02 |
| PoC Study to Evaluate the Efficacy and Safety of Secukinumab 300 mg in Patients With Lichen Planus secukinumab 300 mg Q4W, secukinumab 300 mg Q2W, Placebo - Lichen Planus: Cutaneous Lichen Planus, Mucosal Lichen Planus and Lichen Planopilaris | Phase 2 | Completed | Novartis Pharmaceuticals | 111 | 2020-07-27 | 2023-08-22 |
| Evaluation of the Effectiveness of Photodynamic Therapy in the Treatment of Lesions of the Lichen Planus Type in the Oral Mucosa and Its Diagnostics With the Use of Autofluorescence, in Various Wavelength Ranges, in Combination With the Use of Texture Analysis and Fractal Dimension PDT Therapy, Triamcinolone (Substance) therapy side - Oral Lichen Planus | Phase 2 | Completed | Wroclaw Medical University | 30 | 2020-02-08 | 2021-08-05 |
| Oral Low-Dose Naltrexone for Lichen Planopilaris and Frontal Fibrosing Alopecia Low-Dose Naltrexone - Lichen Planopilaris, Frontal Fibrosing Alopecia | Phase 2 | Completed | Washington University School of Medicine | 43 | 2019-09-01 | 2021-12-30 |
| A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases KPL-716, Placebo - Chronic Idiopathic Urticaria, Chronic Idiopathic Pruritus | Phase 2 | Completed | Genentech, Inc. | 58 | 2019-05-29 | 2025-03-18 |
| Topical Ruxolitinib Lichen Planus INCB018424 - Lichen Planus | Phase 2 | Completed | Aaron R. Mangold | 12 | 2018-08-30 | 2021-08-04 |
| Intra-oral Treatment of OLP With Rivelin®-CLO Patches Clobetasol Propionate - Oral Lichen Planus | Phase 2 | Completed | Dermtreat | 140 | 2018-06-28 | 2020-07-14 |
| Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions. Ibuprofen suspension 5mg/100ml, Placebos - Oral Lichen Planus, Oral Lichenoid Mucositis | Phase 2 / Phase 3 | Completed | University of Washington | 23 | 2018-04-29 | 2020-05-08 |
| Valchlor in the Treatment of Lichen Planopilaris Mechlorethamine 0.016% Top Gel - Lichen Planopilaris | Phase 2 | Completed | Mayo Clinic | 12 | 2018-04-01 | 2021-01-28 |
| Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus Platelet rich plasma, Triamcinolone Acetonide - Erosive Oral Lichen Planus | Phase 2 | Completed | Cairo University | 20 | 2018-01-01 | 2023-02-09 |
| Effect of Bifidobacterium Animalis Subsp. Lactis HN019 on Oral Lichen Planus Bifidobacterium animalis subsp. lactis HN019, Clobetasol propionate 0.05% - Oral Lichen Planus | Phase 2 | Completed | University of Sao Paulo | 22 | 2017-11-06 | 2020-03-27 |
| Dexamethasone Solution for the Treatment of Oral Lichen Planus Dexamethasone - Lichen Planus | Phase 2 | Completed | Brigham and Women's Hospital | 24 | 2017-02-07 | 2021-06-14 |
Showing 20 of 32. Sign in to see all of them.
Lichen Planus, Oral (22) · Alopecia (1) · Atrophy (1) · Bronchiolitis Obliterans Syndrome (1) · Chronic Urticaria (1) · Neurodermatitis (1) · Oral Ulcer (1) · Pain (1) · Pemphigoid, Benign Mucous Membrane (1) · Pemphigus (1) · Pruritus (1) · Skin Diseases (1) · Stomatitis, Aphthous (1) · Ulcer (1)
Lichenoid Eruptions (32) · Skin Diseases, Papulosquamous (32) · Skin and Connective Tissue Diseases (32) · Skin Diseases (31) · Mouth Diseases (22) · Stomatognathic Diseases (22) · Pathological Conditions, Signs and Symptoms (4) · Immune System Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Anatomical (2) · Signs and Symptoms (2) · Autoimmune Diseases (1) · Bronchial Diseases (1) · Bronchiolitis (1)
Triamcinolone Acetonide (4) · Dexamethasone (3) · Photochemotherapy (3) · Adrenal Cortex Hormones (2) · Clobetasol (2) · Solutions (2) · Triamcinolone (2) · baricitinib (2) · 1-phenyl-3,3-dimethyltriazene (1) · Amines (1) · Diarylheptanoids (1) · Doxycycline (1) · Glycyrrhiza glabra extract (1) · Hydroxychloroquine (1) · Intercellular Signaling Peptides and Proteins (1)
Wroclaw Medical University (3) · Aaron R. Mangold (2) · Mashhad University of Medical Sciences (2) · Mayo Clinic (2) · National Institute of Dental and Craniofacial Research (NIDCR) (2) · Brigham and Women's Hospital (1) · Cairo University (1) · College of Dental Sciences, India (1) · Dermtreat (1) · Emma Guttman (1) · Genentech, Inc. (1) · Goa Dental College (1) · Incyte Corporation (1) · Isfahan University of Medical Sciences (1) · Ivan Alajbeg (1)
United States (18) · Iran (3) · Poland (3) · Canada (2) · Egypt (2) · Germany (2) · India (2) · Brazil (1) · Croatia (1) · Denmark (1) · France (1) · Ireland (1) · United Kingdom (1)
Aaron Mangold, MD (1) · Aaron R Mangold (1) · Aaron R Mangold, MD (1) · Alessandro Villa, DDS, PhD, MPH (1) · Arash Mansourian, DDS,MS (1) · Christopher Hull, MD (1) · Donna Culton, MD, PhD (1) · Dr MC Shashikanth, MDS (1) · Ellen E Monteiro, Student (1) · Emma Guttman-Yassky, MD, PhD (1) · Enas Elgendy, ph.D (1)
PMID 21175873, PMID 21907450, PMID 33831097, PMID 35131254, PMID 35218680, PMID 36197049, PMID 37505393, PMID 37549933, PMID 37794275, PMID 38260663, PMID 39951132, PMID 42776548
2019 (1)