10 completed, 1 unknown, 1 withdrawn. 5 Not applicable, 5 Phase 2, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 5 |
| Phase 2 | 5 | Completed 3, Unknown 1, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow this drug Literature Review of Amines trials Research Report on Amines
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL Hypericin, Mechlorethamine Topical Gel - Cutaneous T-Cell Lymphoma/Mycosis Fungoides | Phase 2 | Completed | Soligenix | 10 | 2023-12-05 | 2025-08-20 |
| Broccoli Seed Extract and Skin Health Broccoli, mustard, vitamin C, Placebo - Skin Inflammation | Not applicable | Completed | Appalachian State University | 24 | 2023-03-13 | 2023-12-20 |
| Deep Phenotyping of Cutaneous T Cell Lymphoma, Type Mycosis Fungoides Chlormethine - Mycosis Fungoides | Not applicable | Completed | Centre for Human Drug Research, Netherlands | 32 | 2021-12-07 | 2023-01-25 |
| Low Dose Total Skin Electron Beam Radiation Therapy and Mechlorethamine Hydrochloride Gel in Treating Patients With Mycosis Fungoides Mechlorethamine Hydrochloride Gel, Total Skin Electron Beam Radiation Therapy - Mycosis Fungoides | Phase 2 | Withdrawn | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 2018-08-01 | 2025-04-29 | |
| Valchlor in the Treatment of Lichen Planopilaris Mechlorethamine 0.016% Top Gel - Lichen Planopilaris | Phase 2 | Completed | Mayo Clinic | 12 | 2018-04-01 | 2021-01-28 |
| Mechlorethamine Induced Contact Dermatitis Avoidance Study Triamcinolone, Valchlor 0.016 % Topical Gel - Cutaneous T-cell Lymphoma, Cutaneous T-cell Lymphoma Stage I | Phase 2 | Completed | Rochester Skin Lymphoma Medical Group, PLLC | 28 | 2017-12-13 | 2026-09-04 |
| Effect of Vitamin D After Application With Valchlor 4 placebo, 4 Vitamin D, Valchlor - Skin Irritation | Early Phase 1 | Completed | University Hospitals Cleveland Medical Center | 33 | 2016-11-17 | 2021-12-23 |
| Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoides Total skin electron beam therapy (TSEBT), mechlorethamine gel 0.016% - Mycosis Fungoides, Cutaneous T-cell Lymphoma | Phase 2 | Unknown | Thomas Jefferson University | 68 | 2016-09-01 | 2016-08-30 |
| Footbaths With Ginger, Mustard & Warm Water Only in Female Adolescents With & Without Anorexia Nervosa Warm water, Mustard, Ginger - Anorexia Nervosa | Not applicable | Completed | ARCIM Institute Academic Research in Complementary and Integrative Medicine | 41 | 2015-12-15 | 2018-05-09 |
| Clinical Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell Lymphoma Valchlor - Mycosis Fungoides | Completed | Helsinn Therapeutics (U.S.), Inc | 300 | 2014-11-12 | 2020-03-04 | |
| Effects of a Specific Spice on Energy Metabolism Mustard (dijon), Placebo - Healthy | Not applicable | Completed | University of Copenhagen | 16 | 2008-08-01 | 2009-02-11 |
| Examination of the Effects of Four Different Spices on Energy Metabolism ginger, black pepper, horseradish - Healthy | Not applicable | Completed | University of Copenhagen | 22 | 2006-10-01 | 2008-02-08 |
Mycosis Fungoides (6) · Lymphoma, T-Cell, Cutaneous (4) · Anorexia Nervosa (1) · Dermatitis (1) · Dermatitis, Contact (1) · Inflammation (1) · Lichen Planus (1) · Neoplasms (1)
University of Copenhagen (2) · ARCIM Institute Academic Research in Complementary and Integrative Medicine (1) · Appalachian State University (1) · Centre for Human Drug Research, Netherlands (1) · Helsinn Therapeutics (U.S.), Inc (1) · Mayo Clinic (1) · Rochester Skin Lymphoma Medical Group, PLLC (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · Soligenix (1) · Thomas Jefferson University (1) · University Hospitals Cleveland Medical Center (1)
United States (7) · Denmark (2) · Germany (1) · Netherlands (1)
Arne Astrup, Professor MD (2) · Bill Bailey (1) · Brian Poligone, MD, PhD (1) · Camila A Olson, PhD (1) · Jan Vagedes, Dr. (1) · Jason Sluzevich, MD (1) · Joya Sahu, MD (1) · Kurt Lu, MD (1) · Robert Rissmann, Prof. Dr. (1)
PMID 23021155, PMID 35122614, PMID 36692020, PMID 41920467
U01AR064144 (1)