19 completed, 7 recruiting, 6 unknown, 2 terminated. 12 Not applicable, 4 Phase 2, 3 Phase 4, 1 Early Phase 1, 1 Phase 1.
Follow Lentigo: new trials by email Literature Review of Lentigo trials Research Report on Lentigo
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chinese Multicenter Registry for Peutz-Jeghers Syndrome Peutz-Jeghers Syndrome | Recruiting | First People's Hospital of Hangzhou | 1000 | 2026-11-01 | 2026-11-12 | |
| Celecoxib for Prevention of Progression in Peutz-Jeghers Syndrome Celecoxib 400mg, Placebo - Peutz-Jeghers Syndrome, Celecoxib | Not applicable | Recruiting | Air Force Military Medical University, China | 80 | 2025-02-01 | 2025-05-30 |
| Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face CRYONOVE (EC14_4osc), CRYONOVE (EC05osc) - Lentigo, Solar Lentigo | Not applicable | Completed | Cryonove Pharma | 30 | 2024-09-16 | 2024-12-24 |
| Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face CRYONOVE (EC14_4osc), CRYONOVE (EC+05_1osc), CRYONOVE (EC+05_2osc) - Lentigo, Solar Lentigo | Not applicable | Unknown | Cryonove Pharma | 45 | 2024-04-01 | 2024-04-17 |
| Cold Snare Polypectomy for Small Bowel Polyps in Patients With Peutz-Jeghers Syndrome Cold snare polypectomy - Peutz-Jeghers Syndrome, Small Bowel Polyp | Phase 4 | Unknown | Shandong University | 40 | 2023-08-20 | 2023-08-21 |
| Poorly Differentiated Adenocarcinoma of the Jejunum in a Patient With Peutz-Jeghers Syndrome: A Case Report Peutz-Jeghers Syndrome | Completed | Haramaya Unversity | 1 | 2023-07-15 | 2024-02-06 | |
| TCA 15% Chemical Peel for Improvement in Hand Lentigines 15% Trichloroacetic acid + 3% glycolic acid - Photoaging, Lentigo | Phase 4 | Completed | Main Line Center for Laser Surgery | 20 | 2023-03-15 | 2025-03-17 |
| Comparison of 3 in Vivo Microscopic Imaging Techniques for the Diagnosis of Pigmented Tumors Fluorescence-Advanced videodermatoscopy, Reflectance confocal microscopy, Super-high magnification dermoscopy - Basal Cell Carcinoma, Lentigo Maligna | Completed | Centre Hospitalier Universitaire de Saint Etienne | 161 | 2022-11-02 | 2024-06-24 | |
| The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics Data collection - Pancreatic Ductal Adenocarcinoma, Pancreatic Cyst | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 317 | 2022-10-06 | 2026-09-15 | |
| Inherited Cancer Early Diagnosis (ICED) Study Li Fraumeni Syndrome, Lynch Syndrome | Unknown | Royal Marsden NHS Foundation Trust | 100 | 2022-07-26 | 2023-12-08 | |
| Tolerance and Mode of Administration of Cyto-selective Cryotherapy Treatments in Face Brown Spots: Proof of Concept (810A-v1) device prototype, (810B-v1) device prototype, (810C-v1) device prototype - Solar Lentigo | Not applicable | Completed | Cryonove Pharma | 23 | 2021-12-15 | 2022-08-19 |
| Registry of Subjects at Risk of Pancreatic Cancer MRCP, Endoultrasonography - Familial Pancreatic Cancer, BRCA1 Mutation | Recruiting | Associazione Italiana per lo Studio del Pancreas | 1000 | 2019-08-20 | 2023-01-13 | |
| Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers Syndrome Rapamycin - Peutz-Jeghers Syndrome | Phase 4 | Unknown | Peking Union Medical College Hospital | 10 | 2018-09-16 | 2019-01-23 |
| Study of Accurate Diagnosis and Treatment of Peutz-Jeghers Syndrome Second generation sequencing, 16s rRNA gene sequencing - Peutz-Jeghers Syndrome | Not applicable | Unknown | Yiqi Du | 150 | 2018-03-01 | 2019-01-16 |
| RASopathy Biorepository RAS Mutation, Neurofibromatosis 1 | Recruiting | Children's Hospital Medical Center, Cincinnati | 1000 | 2017-06-27 | 2025-12-18 | |
| Familial Investigations of Childhood Cancer Predisposition Acute Leukemia, Adenomatous Polyposis | Recruiting | St. Jude Children's Research Hospital | 1500 | 2017-04-06 | 2026-06-17 | |
| A Single-Center 2-Arm Study for Lentigines on the Hands Enlighten Laser, Excel V Laser - Lentigines | Not applicable | Completed | Cutera Inc. | 24 | 2016-04-01 | 2023-06-02 |
| Hormonal Sensitivity in Patients With Noonan and LEOPARD Syndromes Noonan Syndrome, LEOPARD Syndrome | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 27 | 2015-12-16 | 2021-08-26 | |
| Pancreatic Cancer Screening of High-Risk Individuals in Arkansas Pancreatic Cancer Screening Pathway 1, Pancreatic Cancer Screening Pathway 2 - Pancreatic Neoplasms, Peutz-Jegher's Syndrome | Not applicable | Withdrawn | University of Arkansas | 2015-11-01 | 2019-07-29 | |
| A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin enLighten Laser - Melasma, Lentigines | Not applicable | Completed | Cutera Inc. | 80 | 2015-04-01 | 2017-01-31 |
Showing 20 of 37. Sign in to see all of them.
Peutz-Jeghers Syndrome (22) · Colorectal Neoplasms, Hereditary Nonpolyposis (9) · Pancreatic Neoplasms (7) · Hyperpigmentation (6) · Dysplastic Nevus Syndrome (4) · Hereditary pancreatitis (4) · Adenomatous Polyposis Coli (3) · Hamartoma Syndrome, Multiple (3) · Li-Fraumeni Syndrome (3) · Melanosis (3) · Noonan Syndrome (3) · Ataxia Telangiectasia (2) · Breast Neoplasms (2) · Carney Complex (2)
Skin and Connective Tissue Diseases (37) · Pigmentation Disorders (36) · Skin Diseases (36) · Melanosis (34) · Hyperpigmentation (31) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (24) · Genetic Diseases, Inborn (23) · Neoplastic Syndromes, Hereditary (23) · Digestive System Diseases (22) · Gastrointestinal Diseases (22) · Intestinal Diseases (22) · Intestinal Polyposis (22) · Neoplasms (22) · Neoplasms by Site (15)
Secretin (3) · Everolimus (2) · Anesthetics, Local (1) · Biopsy, Fine-Needle (1) · CA-19-9 Antigen (1) · Celecoxib (1) · Cryotherapy (1) · Data Collection (1) · Endoscopic Ultrasound-Guided Fine Needle Aspiration (1) · Lasers (1) · Lidocaine (1) · Magnetic Resonance Spectroscopy (1) · Prilocaine (1) · Sirolimus (1) · Tetracaine (1)
Cryonove Pharma (3) · Cutera Inc. (2) · Johns Hopkins University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Air Force Military Medical University, China (1) · Associazione Italiana per lo Studio del Pancreas (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Children's Hospital Medical Center, Cincinnati (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · First People's Hospital of Hangzhou (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Haramaya Unversity (1) · Hexsel Dermatology Clinic (1) · Icahn School of Medicine at Mount Sinai (1) · Institut National de la Santé Et de la Recherche Médicale, France (1)
United States (17) · China (6) · France (2) · Chile (1) · Ethiopia (1) · Italy (1) · Japan (1) · Netherlands (1) · Singapore (1) · South Africa (1) · Thailand (1) · Ukraine (1) · United Kingdom (1)
Aimee Lucas, MD, MS (1) · Angela George (1) · David Renton, MD (1) · Deborah P Merke, M.D. (1) · Doris Hexsel, MD (1) · Emilia M Zegpi, MD (1) · Heinz-Josef Klumpen, MD (1) · Henry Hin-Lee Chan, M.D., Ph.D (1) · Jiaolin Zhou, MD (1) · Kachiu Lee, MD (1) · Kathryn N Weaver, MD (1) · Kei Negishi, M.D., Ph.D (1) · Kelly Stankiewicz, MD FAAD (1)
PMID 11096382, PMID 16631967, PMID 18021205, PMID 20458532, PMID 21384391, PMID 22154461, PMID 23200980, PMID 24292155, PMID 24854088, PMID 25481712, PMID 29371475, PMID 30538291, PMID 31197699, PMID 31676359, PMID 32118343, PMID 32893266, PMID 33161160, PMID 34149034, PMID 37099777, PMID 37787643, PMID 38460193, PMID 42544942, PMID 7963648
R01CA176828 (1), U01CA210170 (1)