7 completed, 5 recruiting, 4 unknown, 2 terminated. 4 Not applicable, 3 Phase 2, 2 Phase 4, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 1, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 3 | Terminated 2, Withdrawn 1 |
| Phase 4 | 2 | Unknown 2 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Peutz-Jeghers Syndrome: new trials by email Literature Review of Peutz-Jeghers Syndrome trials Research Report on Peutz-Jeghers Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chinese Multicenter Registry for Peutz-Jeghers Syndrome Peutz-Jeghers Syndrome | Not yet recruiting | First People's Hospital of Hangzhou | 1000 | 2026-10-01 | 2026-10-29 | |
| Celecoxib for Prevention of Progression in Peutz-Jeghers Syndrome Celecoxib 400mg, Placebo - Peutz-Jeghers Syndrome, Celecoxib | Not applicable | Recruiting | Air Force Military Medical University, China | 80 | 2025-02-01 | 2025-05-30 |
| Cold Snare Polypectomy for Small Bowel Polyps in Patients With Peutz-Jeghers Syndrome Cold snare polypectomy - Peutz-Jeghers Syndrome, Small Bowel Polyp | Phase 4 | Unknown | Shandong University | 40 | 2023-08-20 | 2023-08-21 |
| Poorly Differentiated Adenocarcinoma of the Jejunum in a Patient With Peutz-Jeghers Syndrome: A Case Report Peutz-Jeghers Syndrome | Completed | Haramaya Unversity | 1 | 2023-07-15 | 2024-02-06 | |
| The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics Data collection - Pancreatic Ductal Adenocarcinoma, Pancreatic Cyst | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 317 | 2022-10-06 | 2026-09-15 | |
| Inherited Cancer Early Diagnosis (ICED) Study Li Fraumeni Syndrome, Lynch Syndrome | Unknown | Royal Marsden NHS Foundation Trust | 100 | 2022-07-26 | 2023-12-08 | |
| Registry of Subjects at Risk of Pancreatic Cancer MRCP, Endoultrasonography - Familial Pancreatic Cancer, BRCA1 Mutation | Recruiting | Associazione Italiana per lo Studio del Pancreas | 1000 | 2019-08-20 | 2023-01-13 | |
| Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers Syndrome Rapamycin - Peutz-Jeghers Syndrome | Phase 4 | Unknown | Peking Union Medical College Hospital | 10 | 2018-09-16 | 2019-01-23 |
| Study of Accurate Diagnosis and Treatment of Peutz-Jeghers Syndrome Second generation sequencing, 16s rRNA gene sequencing - Peutz-Jeghers Syndrome | Not applicable | Unknown | Yiqi Du | 150 | 2018-03-01 | 2019-01-16 |
| Familial Investigations of Childhood Cancer Predisposition Acute Leukemia, Adenomatous Polyposis | Recruiting | St. Jude Children's Research Hospital | 1500 | 2017-04-06 | 2026-06-17 | |
| Pancreatic Cancer Screening of High-Risk Individuals in Arkansas Pancreatic Cancer Screening Pathway 1, Pancreatic Cancer Screening Pathway 2 - Pancreatic Neoplasms, Peutz-Jegher's Syndrome | Not applicable | Withdrawn | University of Arkansas | 2015-11-01 | 2019-07-29 | |
| Pancreatic Cancer Early Detection Program Endoscopic Ultrasound, Magnetic Resonance Imaging (MRI) - Pancreatic Cancer, Pancreas Cancer | Completed | White Plains Hospital | 181 | 2014-04-01 | 2026-08-25 | |
| The Cancer of the Pancreas Screening-5 CAPS5)Study Secretin, MRI, Tumor marker gene test with CA19-9 - Pancreas Cancer, Peutz-Jeghers Syndrome (PJS) | Phase 3 | Recruiting | Johns Hopkins University | 9000 | 2014-01-06 | 2026-10-22 |
| Pancreas Registry and High Risk Registry Pancreas Cancer, Pancreatitis | Recruiting | Icahn School of Medicine at Mount Sinai | 1368 | 2013-03-01 | 2026-02-11 | |
| Hereditary Colorectal and Associated Tumor Registry Study Research Registry - Lynch Syndrome, FAP | Completed | University of Pittsburgh | 114 | 2012-04-01 | 2018-02-19 | |
| Study of Everolimus in the Treatment of Advanced Malignancies in Patients With Peutz-Jeghers Syndrome Everolimus - Peutz-Jeghers Syndrome, Neoplastic Processes | Phase 2 | Withdrawn | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2010-10-01 | 2015-04-22 | |
| Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease therapeutic laparoscopic surgery - Adenomatous Polyp, Crohn Disease | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 10 | 2010-05-01 | 2017-12-06 |
| Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers Syndrome Everolimus - Peutz-Jeghers Syndrome | Phase 2 | Terminated | University of Utah | 3 | 2008-11-01 | 2024-09-19 |
| Cancer of the Pancreas Screening Study (CAPS 3) Biopsy, Fine Needle Aspiration (FNA), Secretin (human synthetic) - ChiRhoClin - Pancreatic Neoplasm, Peutz-Jeghers Syndrome | Completed | Johns Hopkins University | 200 | 2006-12-01 | 2021-06-18 | |
| Secretin (ChiRhoStim) Pancreas Perfusion for Pancreatic Adenocarcinoma Synthetic Human Secretin - Pancreatic Cancer | Phase 1 / Phase 2 | Terminated | Mayo Clinic | 4 | 2006-11-01 | 2013-06-24 |
Showing 20 of 22. Sign in to see all of them.
Colorectal Neoplasms, Hereditary Nonpolyposis (9) · Pancreatic Neoplasms (7) · Dysplastic Nevus Syndrome (4) · Hereditary pancreatitis (4) · Adenomatous Polyposis Coli (3) · Hamartoma Syndrome, Multiple (3) · Li-Fraumeni Syndrome (3) · Ataxia Telangiectasia (2) · Breast Neoplasms (2) · Carney Complex (2) · Hereditary Sensory and Autonomic Neuropathies (2) · Juvenile polyposis syndrome (2) · Melanoma, Cutaneous Malignant (2) · Neoplasms (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (22) · Digestive System Diseases (22) · Gastrointestinal Diseases (22) · Genetic Diseases, Inborn (22) · Hyperpigmentation (22) · Intestinal Diseases (22) · Intestinal Polyposis (22) · Lentigo (22) · Melanosis (22) · Neoplastic Syndromes, Hereditary (22) · Pigmentation Disorders (22) · Skin Diseases (22) · Skin and Connective Tissue Diseases (22) · Neoplasms (20) · Neoplasms by Site (14)
Secretin (3) · Everolimus (2) · Biopsy, Fine-Needle (1) · CA-19-9 Antigen (1) · Celecoxib (1) · Data Collection (1) · Endoscopic Ultrasound-Guided Fine Needle Aspiration (1) · Magnetic Resonance Spectroscopy (1) · Sirolimus (1)
Johns Hopkins University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Air Force Military Medical University, China (1) · Associazione Italiana per lo Studio del Pancreas (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · First People's Hospital of Hangzhou (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Haramaya Unversity (1) · Icahn School of Medicine at Mount Sinai (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · Ohio State University Comprehensive Cancer Center (1) · Peking Union Medical College Hospital (1) · Royal Marsden NHS Foundation Trust (1) · Shandong University (1)
United States (13) · China (5) · Ethiopia (1) · Italy (1) · Netherlands (1) · United Kingdom (1)
Aimee Lucas, MD, MS (1) · Angela George (1) · David Renton, MD (1) · Deborah P Merke, M.D. (1) · Heinz-Josef Klumpen, MD (1) · Jiaolin Zhou, MD (1) · Kent D McKelvey, MD (1) · Kim E. Nichols, MD (1) · Marcia I. Canto, M.D. (1) · Michael Goggins, MD (1) · Naoki Takahashi, M.D. (1) · Randall E Brand, MD (1) · Randall W Burt, MD (1) · Scott Kuwada, MD (1) · Shaffer Mok, MD, MBS (1)
PMID 20458532, PMID 22154461, PMID 23200980, PMID 25481712, PMID 29371475, PMID 30538291, PMID 31197699, PMID 31676359, PMID 32893266, PMID 33161160, PMID 34149034, PMID 37099777, PMID 37787643, PMID 42544942
R01CA176828 (1), U01CA210170 (1)