117 completed, 50 unknown, 18 recruiting, 16 terminated. 227 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 227 | Completed 117, Unknown 50, Recruiting 18, Terminated 16, Not yet recruiting 12, Active not recruiting 6, Withdrawn 6, Enrolling by invitation 1, Suspended 1 |
Follow Intraabdominal Infections: new trials by email Literature Review of Intraabdominal Infections trials Research Report on Intraabdominal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Perforated Appendicitis and Postoperative Antibiotics Pilot Trial Postoperative antibiotico-prophylaxis, No postoperative antibiotics - Perforated Appendicitis | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 100 | 2027-01-01 | 2026-09-17 |
| Comparative Study Between Laparoscopic and Open Appendectomy of Complicated Appendicitis Laparoscopic Appendectomy, Open Appendectomy - Appendicitis, Perforated Appendicitis | Not applicable | Not yet recruiting | Assiut University | 100 | 2026-11-01 | 2026-10-16 |
| Laparoscopic vs Open Appendectomy in Obese Patients Open Appendectomy, Laparoscopic Appendectomy - Acute Appendicitis, Appendicitis (Diagnosis) | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 166 | 2026-10-02 | 2026-09-16 |
| Immediate Laparoscopic Appendectomy Versus Interval Laparoscopic Appendectomy for Early Appendicular Mass Immediate Laparoscopic Appendectomy, Interval Laparoscopic Appendectomy - Appendicular Mass, Acute Appendicitis | Not applicable | Not yet recruiting | Assiut University | 100 | 2026-10-01 | 2026-09-23 |
| Laparoscopic Appendectomy: Outcomes of 10 mmHg Versus 15 mmHg Intra-abdominal Pressure Laparoscopic appendectomy with 10 mmHg pneumoperitoneum, Laparoscopic appendectomy with 15 mmHg pneumoperitoneum - Appendectomy, Laparoscopic, Intra Abdominal Pressure | Not applicable | Not yet recruiting | Ankara Etlik City Hospital | 150 | 2026-07-27 | 2026-07-27 |
| Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial) Primary Closure with HIEDI, Delayed Primary Closure with HIEDI - Appendicitis, Surgical Wound Infection | Not applicable | Not yet recruiting | Sana'a University | 200 | 2026-07-01 | 2026-07-07 |
| Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy Pressure Transducer, Traditional Palpation Method - Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness | Not applicable | Recruiting | Ankara Etlik City Hospital | 60 | 2026-06-30 | 2026-07-07 |
| Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy Comprehensive 20-Item Pediatric ERAS Protocol - Appendectomy, Laparoscopic, Acute Appendicitis | Not applicable | Recruiting | Ahmet Burak Doğan, MD | 100 | 2026-06-15 | 2026-10-15 |
| TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence Methods Score-based appendicitis risk classification in teleconsultation - Acute Appendicitis | Not applicable | Not yet recruiting | University Hospital, Angers | 1500 | 2026-06-01 | 2026-03-18 |
| Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic Appendectomy Port-site local anesthesia infiltration, Port-Site Saline Infiltration (Placebo) - Appendectomy, Laparoscopic, Appendicitis Acute | Not applicable | Recruiting | YUNUS YÜKSEL | 300 | 2026-04-24 | 2026-09-17 |
| First Appendectomy Using Revolve Surgical Robotic Arm Revolve Surgical System - RSS - Appendicitis Acute | Not applicable | Not yet recruiting | Unity Health Toronto | 3 | 2026-04-01 | 2026-03-06 |
| Laparoscopic vs Open Appendectomy Laparoscopic appendectomy, Open Appendectomy - Acute Appendicitis, Superficial SSI | Not applicable | Completed | Quaid-e-Azam Medical College | 276 | 2026-01-24 | 2026-09-25 |
| Direct Visualization ERAT Versus Laparoscopic Appendectomy in Adults With Acute Uncomplicated Appendicitis Direct Visualization Endoscopic Retrograde Appendicitis Therapy, Laparoscopic appendectomy - Acute Uncomplicated Appendicitis | Not applicable | Recruiting | Changhai Hospital | 376 | 2025-12-10 | 2026-09-04 |
| Clinical Effects of Ringers Lactate Versus Sterofundin/ Plasmalyte Solution in Patients With Sepsis Ringer's Lactate Crystalloid Solutions, Sterofundin (Bolus of crystalloids) - Post Abdominal Surgery, Sepsis Abdominal | Not applicable | Completed | CMH Lahore Medical College and Institute of Dentistry | 82 | 2025-11-15 | 2026-09-10 |
| Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial. outpatient surgery, Hospitalization - Appendicitis Acute, Gangrenous Appendicitis | Not applicable | Recruiting | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 122 | 2025-11-01 | 2026-04-21 |
| Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCT Cartoon-Assisted Distraction (Şüko Ameliyat Oluyor), Mobile Game - Preoperative Anxiety, Children | Not applicable | Recruiting | Ankara City Hospital Bilkent | 69 | 2025-10-10 | 2026-06-10 |
| Differences In Microbiota Profiles Of Pediatric Appendicitis Cases Appendectomy - Appendicitis Acute, Disbiosis | Not applicable | Completed | Istanbul University | 50 | 2025-08-18 | 2026-10-06 |
| Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic Appendectomy Metallic clip ligation of the appendicular stump, Suture ligation of appendicular stump - Laparoscopic Appendectomy | Not applicable | Not yet recruiting | Jinnah Hospital | 10 | 2025-08-15 | 2025-08-19 |
| Effect of Probiotic's Consumption on Several Markers in Perforated Appendix Patients With Diffuse Peritonitis Lactobacillus plantarum sp Probiotic, Placebo Group - Appendicitis With Perforation, Appendectomy | Not applicable | Active not recruiting | Universitas Padjadjaran | 50 | 2025-08-01 | 2026-03-31 |
| Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure Laparoscopic Appendectomy with application of clips for stump closure, Laparoscopic Appendectomy with ligature for stump closure - Appendicitis | Not applicable | Recruiting | Sohag University | 80 | 2025-07-14 | 2025-08-11 |
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Appendicitis (176) · Peritonitis (39) · Pain (9) · Surgical Wound Infection (9) · Sepsis (7) · Infections (6) · Pain, Postoperative (6) · Agnosia (5) · Disease (5) · Abdominal Abscess (4) · Abscess (3) · Acute Disease (3) · Kidney Failure, Chronic (3) · Shock, Septic (3)
Infections (221) · Digestive System Diseases (215) · Gastroenteritis (177) · Intestinal Diseases (177) · Gastrointestinal Diseases (176) · Cecal Diseases (175) · Pathological Conditions, Signs and Symptoms (70) · Pathologic Processes (50) · Peritoneal Diseases (41) · Signs and Symptoms (26) · Neurologic Manifestations (25) · Postoperative Complications (16) · Inflammation (13) · Disease Attributes (10)
Appendectomy (15) · Metronidazole (8) · Ertapenem (5) · Anti-Bacterial Agents (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Drainage (3) · Hospitalization (3) · Levofloxacin (3) · Moxifloxacin (3) · Observation (3) · Therapeutic Irrigation (3) · Blood Specimen Collection (2) · Cefazolin (2) · Cefotaxime (2) · Ceftriaxone (2)
Assiut University (7) · Turku University Hospital (7) · Children's Mercy Hospital Kansas City (6) · Mansoura University (6) · Helsinki University Central Hospital (3) · Ankara City Hospital Bilkent (2) · Ankara Etlik City Hospital (2) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (2) · Central Hospital, Nancy, France (2) · Centre Hospitalier Universitaire de Nice (2) · Children's National Research Institute (2) · Chulalongkorn University (2) · Fatih Sultan Mehmet Training and Research Hospital (2) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (2) · HJ23 (2)
United States (41) · Turkey (Türkiye) (21) · France (14) · China (11) · Egypt (10) · Finland (10) · South Korea (8) · Canada (6) · Pakistan (6) · Spain (5) · Israel (4) · Italy (4) · Russia (4) · Sweden (4) · Switzerland (4)
Paulina Salminen, MD, PhD (5) · Shawn D St. Peter, MD (4) · David R Flum, MD, MPH (2) · Jaroslaw Kobiela, Prof. (2) · Abut Kebudi, Prof. (1) · Ahmed Nasr, MD (1) · Ahmet Burak Erdem, Assoc. Prof. (1) · Alexander V Sazhin, Prof. (1) · Amy Goldberg, MD (1) · Andrew G Hill, MBChB, MD, FRACS (1) · Andrew Kepner, MD (1) · Andrew W Kirkpatrick, MD (1) · Andrius Macas, profesor (1) · Anupam B Kharbanda, MD, MSc (1)
PMID 21946218, PMID 2239906, PMID 40741675, PMID 10231213, PMID 10571434, PMID 10686977, PMID 11222424, PMID 11257737, PMID 11445675, PMID 12470410, PMID 12538172, PMID 12617727, PMID 12771877, PMID 1303622, PMID 14758472, PMID 15108726, PMID 15109590, PMID 15313139, PMID 15347256, PMID 15448528, PMID 15480707, PMID 15529188, PMID 15529837, PMID 15635603, PMID 15673849, PMID 15836853, PMID 15943731, PMID 16034862, PMID 16108734, PMID 16823647, PMID 16927930, PMID 17040666, PMID 17342966, PMID 17877828, PMID 17943363, PMID 18058085, PMID 18158437, PMID 18304752, PMID 1834266, PMID 18446319, PMID 18553045, PMID 18639246, PMID 18648241, PMID 18931198, PMID 19020142, PMID 19056007, PMID 19141492, PMID 19258346, PMID 19573663, PMID 19760332
R01GM145674 (1)