9 unknown. 9 Phase 2, 3 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Unknown 9 |
| Phase 1 | 3 | Unknown 3 |
| Phase 3 | 2 | Unknown 2 |
Follow Intervertebral Disc Degeneration: new trials by email Literature Review of Intervertebral Disc Degeneration trials Research Report on Intervertebral Disc Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Intradiscal Injection of Autologous BM-MSC in Subjects With Chronic LBP Due to Multilevel Lumbar IDD Autologous BM-MSC, Sham - Intervertebral Disc Degeneration, Chronic Low-back Pain | Phase 2 | Unknown | Fondazione Policlinico Universitario Campus Bio-Medico | 52 | 2021-03-22 | 2025-05-25 |
| Safety Evaluation of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion ART352-L - Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Unknown | Ankasa Regenerative Therapeutics, Inc. | 12 | 2020-09-30 | 2020-10-12 |
| KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion TGplPTH1-34 in fibrin, Autologous Bone Graft - Degenerative Disc Disease, Spinal Fusion | Phase 2 | Unknown | Kuros Biosurgery AG | 50 | 2020-08-27 | 2023-08-09 |
| Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs Bone Marrow Concentrate - Low Back Pain, Disc Disease | Phase 2 / Phase 3 | Unknown | Stem Cures | 80 | 2018-11-21 | 2020-09-22 |
| Fibrin for Chronic Multi-level Discogenic Low Back Pain Fibrin sealant - Low Back Pain, Disc Disease | Phase 2 / Phase 3 | Unknown | Pauza, Kevin, MD | 400 | 2018-06-11 | 2020-11-09 |
| Effectiveness and Safety of Mesenchymal Stem Cell (MSC) Implantation on Degenerative Discus Disease Patients Mesenchymal Stem Cell + NaCl 0,9% 2ml - Degenerative Disc Disease, Low Back Pain | Phase 2 | Unknown | Ahmad Jabir Rahyussalim | 10 | 2017-07-24 | 2020-08-06 |
| Efficiency and Safety Study of Pamidronate in Inflammatory Back Pain Due to Degenerative Disk Disease Pamidronate, Placebo - Intervertebral Disc Degeneration, Modic I Discopathy | Phase 2 | Unknown | University Hospital, Clermont-Ferrand | 48 | 2013-01-01 | 2013-02-27 |
| Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules, Iliac crest autograft - Degenerative Disc Disease, Spondylolisthesis | Phase 1 / Phase 2 | Unknown | BioSurface Engineering Technologies, Inc | 22 | 2008-11-01 | 2012-03-09 |
| Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules, Iliac crest autograft - Degenerative Disc Disease, Spondylolisthesis | Phase 1 / Phase 2 | Unknown | BioSurface Engineering Technologies, Inc | 24 | 2008-11-01 | 2012-03-09 |
Low Back Pain (5) · Spondylolisthesis (3) · Back Pain (2) · Radiculopathy (2) · Sciatica (1) · Spinal Stenosis (1)
Bone Diseases (9) · Musculoskeletal Diseases (9) · Spinal Diseases (9) · Neurologic Manifestations (6) · Pain (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Back Pain (4) · Spondylolysis (3) · Spondylosis (3) · Nervous System Diseases (2) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2) · Mononeuropathies (1) · Neuralgia (1)
Fibrin (1) · Fibrin Tissue Adhesive (1) · Pamidronate (1) · Therapeutics (1) · salicylhydroxamic acid (1)
BioSurface Engineering Technologies, Inc (2) · Ahmad Jabir Rahyussalim (1) · Ankasa Regenerative Therapeutics, Inc. (1) · Fondazione Policlinico Universitario Campus Bio-Medico (1) · Kuros Biosurgery AG (1) · Pauza, Kevin, MD (1) · Stem Cures (1) · University Hospital, Clermont-Ferrand (1)
United States (5) · Canada (1) · France (1) · Indonesia (1) · Italy (1)
Brent Atkinson, PhD (1) · David M Hooper, PhD (1) · John Chi, MD (1) · Kevin Pauza, MD (1) · Sairam Atluri, MD (1)
2019 (1)