321 completed. 321 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 321 | Completed 321 |
Follow Inflammation: new trials by email Literature Review of Inflammation trials Research Report on Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Oral Nicotinamide as an Adjunctive Therapy in Patients With Sepsis Nicotinamide 1000 mg - Sepsis - to Reduce Mortality in the Intensive Care Unit | Phase 4 | Completed | Ain Shams University | 60 | 2026-03-28 | 2026-10-20 |
| Continuous Infusion Versus Intermittent Bolus Hydrocortisone in Septic Shock Hydrocortisone Continuous Infusion, Hydrocortisone Intermittent Bolus - Septic Shock | Phase 4 | Completed | Benha University | 110 | 2026-01-01 | 2026-07-10 |
| Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery Ibuprofen (400 mg x 4), Placebo (NaCl 0.9 % solution) - Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery | Phase 4 | Completed | Mehmet Çiğdem | 76 | 2025-09-27 | 2026-03-03 |
| Effect of Vitamin D as Adjuvant Therapy in Preterm Infants With Neonatal Sepsis Vitamin D - Neonatal Sepsis, Preterm Infants | Phase 4 | Completed | Universitas Padjadjaran | 78 | 2025-08-02 | 2026-02-05 |
| Skin Barrier Function and Inflammation in Aging: The BIA Study CeraVe Moisturizing Cream, Vaseline - Inflammation, Skin Inflammation | Phase 4 | Completed | University of California, San Francisco | 32 | 2025-02-06 | 2026-07-14 |
| PFAS Exposure and Immune Response to Vaccination in Adults TENIVAC - Innate Inflammatory Response, Vaccination | Phase 4 | Completed | Rutgers, The State University of New Jersey | 20 | 2024-11-04 | 2025-12-30 |
| Effect of Influenza Vaccination on Global Systemic Inflammatory Markers in Patients With Stable Coronary Artery Disease Influenza Vaccination - Coronary Artery Disease, Inflammatory Response | Phase 4 | Completed | University Hospital, Tours | 47 | 2024-10-21 | 2025-11-21 |
| Comparing Oral Lumbrokinase DLBS1033 and Betahistine Mesylate in Benign Paroxysmal Positional Vertigo DLBS1033, Betahistine Mesylate tablet - Benign Paroxysmal Positional Vertigo (Disorder) | Phase 4 | Completed | Universitas Sebelas Maret | 44 | 2024-04-01 | 2025-07-20 |
| EFFICACY OF PROLONGED INFUSION MEROPENEM IN CRITICALLY ILL PAEDIATRIC INTENSIVE CARE PATIENTS Meropenem Infusion - Sepsis, Bacterial Infection | Phase 4 | Completed | Pakistan Navy Station Shifa Hospital | 150 | 2024-04-01 | 2025-08-14 |
| Vasopressin for Septic Shock Pragmatic Trial Vasopressin, Recommendation to use a lower initiation threshold for vasopressin, Recommendation to use a higher initiation threshold for vasopressin - Septic Shock | Phase 4 | Completed | Intermountain Health Care, Inc. | 3959 | 2024-02-01 | 2026-08-03 |
| Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients Acetaminophen, Ibuprofen - Sepsis, Acetaminophen | Phase 4 | Completed | Ankara City Hospital Bilkent | 113 | 2023-10-31 | 2025-02-04 |
| Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction Carboxytherapy, Placebo - Liposuction, Bruising | Phase 4 | Completed | Total Definer Research Group | 72 | 2023-09-01 | 2026-07-21 |
| High-dose Cephalexin for Cellulitis (HI-DOCC) Cephalexin - Cellulitis | Phase 4 | Completed | Ottawa Hospital Research Institute | 454 | 2023-08-30 | 2026-08-03 |
| The Effects of Oxycodone Versus Sufentanil on Pain and Inflammatory Response After TACE Oxycodone, Sufentanil - Hepatocellular Carcinoma, Transcatheter Arterial Chemoembolization | Phase 4 | Completed | The First Affiliated Hospital with Nanjing Medical University | 40 | 2023-08-07 | 2024-02-28 |
| Single Vs Multi-strain Probiotics for Preterm Neonates Dextrose 10%, Lactobacillus Rhamnosus GG, Bifidobacterium BB-12, Lactobacillus paracasei, L casei-431, Streptococcus thermophilus TH-4 - Necrotizing Enterocolitis of Newborn, Sepsis Newborn | Phase 4 | Completed | Madiha, MPhil | 249 | 2023-05-15 | 2025-12-22 |
| Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock Angiotensin II - Septic Shock, Vasodilatory Shock | Phase 4 | Completed | University of New Mexico | 42 | 2023-04-17 | 2026-07-02 |
| Evaluation of Catheter Associated Urinary Tract Infection Between Metal Alloy Coated Catheter and Conventional Latex Catheter in Critically Ill Patients Latex metal alloy coated catheter, conventional latex urinary catheter - Sepsis, Urosepsis | Phase 4 | Completed | National University of Malaysia | 76 | 2023-03-01 | 2025-02-03 |
| Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function Rocuronium Bromide - Neuromuscular Blockade, Innate Inflammatory Response | Phase 4 | Completed | Radboud University Medical Center | 100 | 2022-11-18 | 2024-09-19 |
| Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China test product (T) azithromycin capsule and reference product (R) azithromycin capsule "Sumamed®" - Upper Respiratory Tract Infection, Lower Respiratory Infection | Phase 4 | Completed | Peking University People's Hospital | 48 | 2022-11-16 | 2023-11-28 |
| Body and Social Behavior Influenza vaccine, Placebo - Psychology, Social, Inflammation | Phase 4 | Completed | University of North Carolina, Chapel Hill | 104 | 2022-10-17 | 2024-11-27 |
Showing 20 of 321. Sign in to see all of them.
Sepsis (70) · Shock, Septic (38) · Bacteremia (16) · Cellulitis (15) · Systemic Inflammatory Response Syndrome (13) · Infections (12) · Diabetes Mellitus, Type 2 (11) · Pain (11) · Atherosclerosis (10) · Kidney Failure, Chronic (10) · Insulin Resistance (9) · Neonatal Sepsis (9) · Obesity (8) · Abscess (7)
Pathologic Processes (321) · Pathological Conditions, Signs and Symptoms (321) · Infections (149) · Systemic Inflammatory Response Syndrome (121) · Sepsis (53) · Shock (50) · Signs and Symptoms (41) · Cardiovascular Diseases (39) · Nutritional and Metabolic Diseases (34) · Vascular Diseases (34) · Bacterial Infections and Mycoses (33) · Urogenital Diseases (31) · Skin and Connective Tissue Diseases (29) · Disease Attributes (28)
Sodium Chloride (12) · Atorvastatin (8) · Saline Solution (8) · Celecoxib (6) · Daptomycin (6) · drotrecogin alfa activated (6) · Anidulafungin (5) · Ascorbic Acid (5) · Dexmedetomidine (5) · Hydrocortisone (5) · Vitamin D (5) · Cephalexin (4) · Dexamethasone (4) · Gentamicins (4) · Meropenem (4)
Ain Shams University (7) · Pfizer (6) · Eli Lilly and Company (5) · Emory University (4) · Medical University of Vienna (4) · Radboud University Medical Center (4) · Amgen (3) · Bausch & Lomb Incorporated (3) · Changi General Hospital (3) · Southeast University, China (3) · University Hospital, Basel, Switzerland (3) · University Of Perugia (3) · University of California, San Francisco (3) · University of Padova (3) · University of Pennsylvania (3)
United States (87) · Brazil (18) · Italy (18) · China (16) · Egypt (14) · France (13) · Germany (13) · Netherlands (12) · Switzerland (12) · Canada (11) · Denmark (11) · United Kingdom (11) · Spain (9) · Turkey (Türkiye) (9) · Australia (8)
Bernd Jilma, MD (3) · Alfonso M. M Cueto-Manzano, MD, MSc, PhD (2) · Andrea M Isidori, MD, PhD (2) · Angelo Avogaro, M.D. Ph.D. (2) · Dr R Gopinath (2) · Gian Paolo Fadini, M.D. (2) · Ronald G Collman, MD (2) · Aaron E Chen, MD (1)
PMID 28459966, PMID 28597967, PMID 31280481, PMID 33891293, PMID 11409564, PMID 11529214, PMID 11574381, PMID 11588440, PMID 11771602, PMID 12500513, PMID 12519925, PMID 12710654, PMID 15229100, PMID 15341352, PMID 15343008, PMID 15585684, PMID 15774007, PMID 16113473, PMID 16134766, PMID 16254497, PMID 16632649, PMID 16757502, PMID 16879732, PMID 17355677, PMID 17394957, PMID 17403800, PMID 17556722, PMID 18096708, PMID 18156891, PMID 18211990, PMID 18305265, PMID 18577309, PMID 18707849, PMID 19055828, PMID 19068113, PMID 19104769, PMID 19124814, PMID 19130163, PMID 19222623, PMID 19299807, PMID 19318651, PMID 19383806, PMID 19457240, PMID 19531784, PMID 19554385, PMID 19567860, PMID 19571170, PMID 19686276, PMID 19788787, PMID 19926252
2014 (4), 2015 (4), 2017 (2), 2008 (1), 2016 (1), K23AT002862 (1), M01RR000827 (1), P30AI045008 (1), P30DK063491 (1), R01DK071277 (1), R01DK075877 (1), R01HD097578 (1), R01MH109637 (1), R21AR082620 (1), R21AT004708 (1)