33 not yet recruiting. 33 Phase 2, 4 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 33 | Not yet recruiting 33 |
| Phase 1 | 4 | Not yet recruiting 4 |
| Phase 3 | 3 | Not yet recruiting 3 |
Follow Inflammation: new trials by email Literature Review of Inflammation trials Research Report on Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase IIb Multicenter Randomized Controlled Trial Evaluating the Efficacy of Sivelestat in Patients With Septic Coagulopathy • Sivelestat intravenous infusion, NaCl intravenous infusion - Septic Shock, Coagulopathy | Phase 2 | Not yet recruiting | University Hospital, Strasbourg, France | 120 | 2027-08-01 | 2026-08-20 |
| Effect of Pentadecanoic Acid Supplementation on Red Blood Cell Health and Biological Aging in Healthy Older Adults Pentadecanoic Acid, Placebo - Red Blood Cell Health, Biological Aging | Phase 2 | Not yet recruiting | ReCellience15, Inc | 93 | 2027-01-01 | 2026-10-05 |
| THiamine for Recovery In Vulnerable Early-life Infections thiamine hydrochloride 100 mg, Placebo - Meningitis, Bacteremia | Phase 2 | Not yet recruiting | Milton S. Hershey Medical Center | 240 | 2026-12-01 | 2026-10-09 |
| IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With Obesity IGOB131, Dextrin - Obesity & Overweight | Phase 2 | Not yet recruiting | University of Yaounde 1 | 80 | 2026-12-01 | 2026-10-20 |
| Low Dose Dexamethasone for the Prevention of Cytokine Release Syndrome Associated With Tebentafusp Dexamethasone - Uveal Melanoma, Metastatic | Phase 2 | Not yet recruiting | University of California, San Diego | 34 | 2026-11-01 | 2026-09-03 |
| Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis inulin, Maltodextrin (Placebo) - Knee Osteoarthritis | Phase 2 | Not yet recruiting | Yale University | 84 | 2026-11-01 | 2026-07-07 |
| Ticagrelor for Inflammation and Cardiovascular Risk in Patients With Chronic Kidney Disease Ticagrelor: an oral, direct-acting, reversibly binding P2Y12 receptor antagonist, Placebo - Chronic Kidney Disease (CKD) | Phase 2 | Not yet recruiting | University of Arkansas | 230 | 2026-11-01 | 2026-11-02 |
| Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity Olatorepatide, Placebo - Hidradenitis Suppurativa | Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 300 | 2026-10-30 | 2026-09-21 |
| NAI Plus Standard of Care Compared With Placebo Plus Standard of Care in Critically Ill Adults With Sepsis Nogapendekin alfa inbakicept (NAI), Placebo - Sepsis | Phase 2 | Not yet recruiting | ImmunityBio, Inc. | 50 | 2026-10-15 | 2026-09-25 |
| CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock Methylprednisone, Standard of Care (SOC) - Cardiogenic Shock, Heart Failure | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 30 | 2026-10-01 | 2026-08-13 |
| Effect of Adjunctive Ursodeoxycholic Acid on Oxidative Stress, Inflammation, and Organ Dysfunction in Adults With Sepsis Standard medical treatment, Ursodeoxycholic Acid - Sepsis | Phase 2 / Phase 3 | Not yet recruiting | Tanta University | 80 | 2026-10-01 | 2026-10-07 |
| Genistein for the Reduction of Adverse Cardiovascular Events (GRACE) Genistein (Unconjugated Isoflavones 100), Placebo - HIV, Vascular Disease | Phase 1 / Phase 2 | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 60 | 2026-09-30 | 2026-08-25 |
| Disulfiram in Rheumatoid Arthritis Placebo, Disulfiram (DSF) - Rheumatoid Arthritis, Inflammation | Phase 2 | Not yet recruiting | University of Oklahoma | 20 | 2026-09-01 | 2026-07-27 |
| Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans 2-hydroxybenzylamine, Placebo - Salt Sensitivity of Blood Pressure, High Blood Pressure | Phase 2 | Not yet recruiting | Vanderbilt University Medical Center | 20 | 2026-09-01 | 2026-07-28 |
| Effects of Curcumin-Piperine Supplementation in Fibromyalgia Curcumin - Piperine, Placebo - Fibromyalgia (FM) | Phase 2 | Not yet recruiting | Ain Shams University | 80 | 2026-08-01 | 2026-08-11 |
| Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients Melatonin - Therapy, Treatment | Phase 2 / Phase 3 | Not yet recruiting | Ain Shams University | 64 | 2026-07-21 | 2026-07-23 |
| Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses Methylene Blue, Lipid Emulsion, Insertion of optical fiber - Abscess | Phase 2 | Not yet recruiting | University of Rochester | 120 | 2026-07-15 | 2026-02-10 |
| NAI for Sepsis With Persistent Lymphopenia Nogapendekin alfa inbakicept (NAI), Standard of Care (SOC) - Sepsis, Septic Shock | Phase 2 | Not yet recruiting | ImmunityBio, Inc. | 50 | 2026-07-06 | 2026-05-11 |
| Study of Protection And Repair of Endothelial-glycocalyx in Sepsis (SPARES) Fresh Frozen Plasma (blood product), MVI and lactated ringers - Sepsis | Phase 2 | Not yet recruiting | Beth Israel Deaconess Medical Center | 45 | 2026-07-01 | 2026-04-22 |
| Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal Disease Anakinra (interleukin-1 receptor antagonist), Placebo Comparator (0.9% NaCl) - Postprandial Hypoglycemia, End-stage Renal Disease (ESRD) | Phase 2 | Not yet recruiting | Marc Donath | 1 | 2026-07-01 | 2026-05-12 |
Showing 20 of 33. Sign in to see all of them.
Sepsis (9) · Shock, Septic (5) · Obesity (4) · Critical Illness (3) · Abscess (2) · Insulin Resistance (2) · Overweight (2) · Weight Loss (2) · Acute Kidney Injury (1) · Agnosia (1) · Arthritis, Rheumatoid (1) · Bacteremia (1) · Cardiovascular Diseases (1) · Carotid Artery Diseases (1)
Pathologic Processes (33) · Pathological Conditions, Signs and Symptoms (33) · Infections (16) · Systemic Inflammatory Response Syndrome (14) · Shock (7) · Signs and Symptoms (7) · Disease Attributes (6) · Nervous System Diseases (6) · Nutritional and Metabolic Diseases (6) · Cardiovascular Diseases (5) · Male Urogenital Diseases (5) · Urogenital Diseases (5) · Vascular Diseases (5) · Body Weight (4)
ALT-803 (2) · Methylene Blue (2) · Standard of Care (2) · 2-(aminomethyl)phenol (1) · 2-Propanol (1) · Calcium Dobesilate (1) · Control Groups (1) · Curcumin (1) · Dexamethasone (1) · Dextrins (1) · Disulfiram (1) · Fat Emulsions, Intravenous (1) · Fenofibrate (1) · Genistein (1) · IGOB131 (1)
Ain Shams University (2) · ImmunityBio, Inc. (2) · Tanta University (2) · Beth Israel Deaconess Medical Center (1) · Brigham and Women's Hospital (1) · British Columbia Cancer Agency (1) · Dongzhimen Hospital, Beijing (1) · Hamilton Health Sciences Corporation (1) · Hitit University (1) · John Basmaji (1) · Klaus Gottlob Müller (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Marc Donath (1) · MetroWest Artificial Intelligence Research Workgroup (1) · Milton S. Hershey Medical Center (1)
United States (9) · Canada (4) · Switzerland (3) · Egypt (2) · China (1) · France (1) · India (1)
Ashwani K Sharma, MD (1) · Beatriz Y Hanaoka, MD, MSc (1) · Bruce Brown (1) · Eleah Stringer, MSc, RD, CSO (1) · Eric Silverman, M.D. (1) · Evelyn Hsieh, MD, PhD (1) · Jin Liu, Dr (1) · John Basmaji (1) · Laurie Christensen, BS (1) · Lennie Sender, MD (1) · Mark JK Chandy, MD PhD (1) · Martin Schlaepfer, PD (1) · Matthias Hepprich, PD Dr. med. (1) · Nishank Jain, M.D. (1)
PMID 11230313, PMID 11588440, PMID 12147930, PMID 12500513, PMID 12519925, PMID 14759425, PMID 16134766, PMID 17698886, PMID 1846122, PMID 18477932, PMID 1860713, PMID 1879381, PMID 21246318, PMID 26683506, PMID 27673307, PMID 28723883, PMID 29151412, PMID 29508706, PMID 29936590, PMID 30231909, PMID 32270211, PMID 32453920, PMID 32520577, PMID 34719443, PMID 3522418, PMID 36237547, PMID 36705345, PMID 36915146, PMID 37534363, PMID 37675576, PMID 39384243, PMID 40009025, PMID 41052782, PMID 42369177, PMID 8648456, PMID 9250657
2025 (1), R01HD122957 (1), R01HL187306 (1), R61AT013472 (1)