53 completed, 23 unknown, 8 recruiting, 6 terminated. 101 Phase 1, 37 Phase 2.
Follow Infertility: new trials by email Literature Review of Infertility trials Research Report on Infertility
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SCLife®-UT hUC-MSCs Advanced Therapy Medicinal Products (hUC-MSCs ATMPs) for Patients With Thin Endometrial Infertility human umbilical cord mesenchymal stem cell complex collagen, intrauterine injection - Infertility, Female | Phase 1 | Suspended | Sclnow Biotechnology Co., Ltd. | 24 | 2026-12-31 | 2026-04-23 |
| Opt-IVF for Personalized Medicine for Normal Responders Opt-IVF, control - Ivf | Phase 1 / Phase 2 | Active not recruiting | Urmila DIwekar | 100 | 2026-10-15 | 2026-11-03 |
| Drospirenone-Primed Ovarian Stimulation Versus GnRH Antagonist Protocol in Poor Ovarian Responders Undergoing Freeze-All IVF/ICSI Drospirenone drug, Cetrorelix 0.25 mg - Poor Ovarian Reserve, Infertility (IVF Patients) | Phase 1 / Phase 2 | Not yet recruiting | Ahmed Saad | 100 | 2026-08-01 | 2026-07-30 |
| A Novel Aromatase Inhibitor, Leflutrozole, for Treatment of Non-Obstructive Azoospermia Leflutrozole, Dose 2 - Infertility Due to Azoospermia, Infertility, Male | Phase 1 / Phase 2 | Active not recruiting | Martin Blomberg Jensen | 15 | 2026-04-21 | 2026-10-21 |
| An Ethno-bridging Study of Pergoveris in Healthy Premenopausal Participants of Japanese or Caucasian Origin Desogestrel and ethinylestradiol fixed dose combination, Follitropin alfa/lutropin alfa - Fertility | Phase 1 | Completed | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 24 | 2025-11-24 | 2026-03-18 |
| An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera Opt-IVF, Control - Infertility (IVF Patients) | Phase 1 / Phase 2 | Recruiting | Urmila DIwekar | 200 | 2025-09-23 | 2025-09-29 |
| A Study to Measure Pharmacokinetic (PK) Concentrations of Gonadotropin-Releasing Hormone Delivered by the OmniPod Pump Lutrepulse - Amenorrhea, Fertility | Phase 1 | Withdrawn | Ferring Pharmaceuticals | 2025-09-12 | 2025-11-14 | |
| A Study to Assess the Bioequivalence of Follitropin Alfa Solution in Pen and Follitropin Alfa Powder in Vial in Healthy Downregulated Male Participants Test: Follitropin alfa, Reference: Follitropin alfa, Zoladex - Hypogonadism | Phase 1 | Completed | EMD Serono Research & Development Institute, Inc. | 55 | 2025-07-21 | 2026-02-24 |
| A Study to Evaluate the Safety and Tolerability of Single and Multiple Dose of STSP-0902 in Healthy Subjects STSP-0902 injection, Placebo - Oligozoospermia | Phase 1 | Recruiting | Staidson (Beijing) Biopharmaceuticals Co., Ltd | 64 | 2025-05-08 | 2026-05-22 |
| Effect of NAE on Polycystic Ovarian Syndrome (PCOS) Herbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg - Polycystic Ovarian Syndrome (PCOS), Infertility | Phase 1 | Completed | Jinnah Sindh Medical University | 116 | 2025-04-10 | 2026-06-22 |
| Study on the Pharmacokinetics and Safety of QL1012D and Gonal-F® in Healthy Female Volunteers QL1012D, Gonal-F® - Infertility, Female | Phase 1 | Active not recruiting | Qilu Pharmaceutical Co., Ltd. | 48 | 2025-04-06 | 2026-02-17 |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Testicular Injury and Oligospermia AlloRx - Testicular Injury, Oligospermia | Phase 1 | Withdrawn | The Foundation for Orthopaedics and Regenerative Medicine | 2025-04-03 | 2025-04-06 | |
| A Study of HS-10518 in Healthy Adult Premenopausal Females in China HS-10518, Placebo - Infertility, Female | Phase 1 | Completed | West China Second University Hospital | 60 | 2025-03-11 | 2026-03-25 |
| NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia Denosumab (Prolia), Letrozole (Aromatase Inhibitors) - Infertility, Male | Phase 1 / Phase 2 | Completed | Martin Blomberg Jensen | 16 | 2025-03-01 | 2026-10-21 |
| Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome Herbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg - Polycystic Ovarian Syndrome (PCOS), Herbal Medicine | Phase 1 | Completed | Jinnah Postgraduate Medical Centre | 116 | 2025-02-22 | 2026-06-23 |
| Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study Mechanically Engineered Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes, Umbilical cord mesenchymal stem cell-derived exosomes, platelet-rich plasma - Thin Endometrial Lining, Female Infertility | Phase 1 / Phase 2 | Recruiting | Tang-Du Hospital | 90 | 2025-02-21 | 2025-03-26 |
| Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product MediReg® Medicinal product MediReg® (Human Mesenchymal Stromal Cell Secretome), lyophilizate for preparation of solution for injection in patients with severe spermatogenesis disorders, Clostilbegit (clomiphene) 50 mg 1 tablet x 1 p a day - 3 months, Triovit - 1 tablet x 1 p a day - 3 months, Folic acid - 1 tablet x 1 p a day - 3 months. - Azoospermia, Nonobstructive, Teratospermia | Phase 1 / Phase 2 | Recruiting | Lomonosov Moscow State University Medical Research and Educational Center | 80 | 2024-11-26 | 2025-03-11 |
| Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome Follicle Stimulating Hormone - Infertility, Obesity | Phase 1 | Recruiting | University of Colorado, Denver | 60 | 2024-10-01 | 2026-10-14 |
| Pharmacokinetics of FSH and hCG Following Multiple Dose of Gonadotropins-IBSA. Gonadotropins Subcutaneous - Ovarian Stimulation, Infertility | Phase 1 | Completed | IBSA Institut Biochimique SA | 28 | 2024-09-23 | 2026-07-16 |
| Pharmacokinetics of FSH and hCG After a Single Subcutaneous Injection of Gonadotropins-IBSA Gonadotropins Subcutaneos - OVARIAN STIMULATION, Infertility | Phase 1 | Completed | IBSA Institut Biochimique SA | 29 | 2024-09-15 | 2026-01-26 |
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Infertility, Female (29) · Infertility, Male (11) · Polycystic Ovary Syndrome (7) · Oligospermia (4) · Aneuploidy (3) · Azoospermia (3) · Primary Ovarian Insufficiency (3) · Anxiety Disorders (2) · Depression (2) · Endometriosis (2) · Gynatresia (2) · Insulin Resistance (2) · Metabolic Diseases (2) · Amenorrhea (1)
Genital Diseases (101) · Urogenital Diseases (101) · Female Urogenital Diseases (37) · Female Urogenital Diseases and Pregnancy Complications (37) · Genital Diseases, Female (37) · Genital Diseases, Male (16) · Male Urogenital Diseases (16) · Endocrine System Diseases (10) · Gonadal Disorders (10) · Adnexal Diseases (9) · Ovarian Diseases (9) · Cysts (7) · Neoplasms (7) · Ovarian Cysts (7)
Sodium Chloride (5) · follitropin alfa (5) · Progesterone (4) · Clomiphene (3) · Ethinyl Estradiol (3) · Filgrastim (3) · Metformin (3) · Acupuncture Therapy (2) · Denosumab (2) · Embryo Transfer (2) · Estradiol (2) · Glycoprotein Hormones, alpha Subunit (2) · Gonadotropin-Releasing Hormone (2) · Granulocyte Colony-Stimulating Factor (2) · Injections (2)
Ain Shams University (4) · Ferring Pharmaceuticals (4) · ART Fertility Clinics LLC (3) · Al-Azhar University (3) · Hadassah Medical Organization (3) · IBSA Institut Biochimique SA (3) · Martin Blomberg Jensen (3) · Royan Institute (3) · Universitair Ziekenhuis Brussel (3) · Alphamab Jilin Co., Ltd. (2) · Center for Human Reproduction (2) · Glycotope GmbH (2) · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany (2) · National and Kapodistrian University of Athens (2) · Sclnow Biotechnology Co., Ltd. (2)
China (20) · United States (20) · Egypt (11) · Iran (5) · Canada (4) · Denmark (4) · Israel (4) · Belgium (3) · United Arab Emirates (3) · Greece (2) · Italy (2) · Netherlands (2) · Pakistan (2) · Russia (2) · Spain (2)
Barbara Lawrenz, PhD (2) · David H Barad, MD, MS (2) · Norbert Gleicher, MD (2) · Sayed Bakry, PhD (2) · Yoel Shufaro, MD PhD (2) · Abd-Elnasr M Ali, MD (1) · Ahmed Abbas, MD (1) · Ahmed Fata, MD (1) · Ahmed Kadeh, MSc (1) · Ahmed S Saad, MD (1) · Aimee Eyvazzadeh, MD, MS, MBA (1) · Anastasia Efimenko, doctor of sciences (1)
PMID 28591833, PMID 22459631, PMID 24406076, PMID 24424357, PMID 25398971, PMID 26303743, PMID 26664408, PMID 28508691, PMID 29375477, PMID 29486615, PMID 30796792, PMID 31029557, PMID 31616379, PMID 31710189, PMID 31900292, PMID 32181337, PMID 32195207, PMID 32720198, PMID 32898291, PMID 34532462, PMID 34711824, PMID 35137345, PMID 36089055, PMID 36273309, PMID 36369425, PMID 36478528, PMID 36537742, PMID 37013570, PMID 38588501, PMID 39152484, PMID 39165278, PMID 39280787, PMID 39643206, PMID 42457811
2023 (2), 2014 (1), 2025 (1), P50HD104224 (1)