110 completed, 49 unknown, 16 recruiting, 16 terminated. 215 Phase 2, 57 Phase 3, 37 Phase 1.
Follow Infertility: new trials by email Literature Review of Infertility trials Research Report on Infertility
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PRECISION-E2: Teverelix in Women With Endometriosis - Pharmacodynamics, Safety and Precision Medicine Correlates Teverelix DP, Teverelix DP Placebo - Endometriosis Pelvic, Endometriosis Ovaries | Phase 2 | Not yet recruiting | Antev Ltd. | 84 | 2027-02-01 | 2026-11-03 |
| Opt-IVF for Personalized Medicine for Normal Responders Opt-IVF, control - Ivf | Phase 1 / Phase 2 | Active not recruiting | Urmila DIwekar | 100 | 2026-10-15 | 2026-11-03 |
| Uterine Transplant in Absolute Uterine Infertility (AUIF) Uterine Transplant - Female Infertility | Phase 2 / Phase 3 | Withdrawn | Brigham and Women's Hospital | 2026-09-01 | 2026-10-15 | |
| Drospirenone-Primed Ovarian Stimulation Versus GnRH Antagonist Protocol in Poor Ovarian Responders Undergoing Freeze-All IVF/ICSI Drospirenone drug, Cetrorelix 0.25 mg - Poor Ovarian Reserve, Infertility (IVF Patients) | Phase 1 / Phase 2 | Not yet recruiting | Ahmed Saad | 100 | 2026-08-01 | 2026-07-30 |
| Triggering Ovulation in Normo-responders Using a Modified Dual Trigger Protocol or HCG Trigger Modified dual trigger, HCG - Infertility (IVF Patients) | Phase 2 | Not yet recruiting | Bedaya Hospital | 196 | 2026-06-01 | 2026-05-06 |
| Triggering Oocyte Maturation in POSEIDON Group 3 and 4 Poor Responders Using Double Trigger or HCG Trigger Double trigger, HCG trigger - Infertility | Phase 2 | Not yet recruiting | Bedaya Hospital | 164 | 2026-06-01 | 2026-05-06 |
| Successive Doses of GnRH Agonist Versus Single Dose of GnRH Agonist to Trigger Ovulation in Hyper-responders Successive doses GnRH agonist, Single dose GnRH agonist - Infertility | Phase 2 | Not yet recruiting | Bedaya Hospital | 190 | 2026-06-01 | 2026-05-11 |
| Can Fat-Burning Shots Boost Fertility? Comparing Weight-Loss Injections vs. Healthy Habits for Obese Men With Low Sperm Health Semaglutide (Rybelsus®), Tirzepatide, Standardized Lifestyle Intervention - Obesity-related Male Infertility | Phase 2 | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 180 | 2026-05-01 | 2025-09-17 |
| A Novel Aromatase Inhibitor, Leflutrozole, for Treatment of Non-Obstructive Azoospermia Leflutrozole, Dose 2 - Infertility Due to Azoospermia, Infertility, Male | Phase 1 / Phase 2 | Active not recruiting | Martin Blomberg Jensen | 15 | 2026-04-21 | 2026-10-21 |
| Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm isotretinoin, Human chorionic gonadotrophin (hCG) - Oligospermia, Azoospermia, Nonobstructive | Phase 2 | Enrolling by invitation | University of Nebraska | 100 | 2026-04-13 | 2026-04-20 |
| A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea Mibavademab, Placebo - Functional Hypothalamic Amenorrhea, FHA | Phase 2 | Recruiting | Regeneron Pharmaceuticals | 34 | 2026-03-11 | 2026-11-04 |
| Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauterine Successful Experience (RISE) REKOVELLE (Follitropin Delta) - Infertility, Insemination | Phase 2 | Recruiting | Centre Hospitalier Intercommunal Creteil | 80 | 2025-12-17 | 2026-04-08 |
| PKB171 Against Placebo in Couples With Mild Male Factor Infertility Intravaginal gel, Vaginal Gel with Applicator - Infertility Due to Azoospermia | Phase 2 / Phase 3 | Recruiting | Prokrea BCN, S.L. | 732 | 2025-10-28 | 2026-06-25 |
| Growth Hormone and Dehydroepiandrosterone Role in Vitro Fertilization Somatropin (4IU for 1 month) plus, folic acid 400 mcg per day., DHEA plus folic acid 400mcg per day, control group - Infertility, Infertility (IVF Patients) | Phase 2 / Phase 3 | Recruiting | Beni-Suef University | 165 | 2025-10-10 | 2026-01-07 |
| An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera Opt-IVF, Control - Infertility (IVF Patients) | Phase 1 / Phase 2 | Recruiting | Urmila DIwekar | 200 | 2025-09-23 | 2025-09-29 |
| NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia Denosumab (Prolia), Letrozole (Aromatase Inhibitors) - Infertility, Male | Phase 1 / Phase 2 | Completed | Martin Blomberg Jensen | 16 | 2025-03-01 | 2026-10-21 |
| Convergent Mechanisms Underlying Reprometabolic Syndrome in Women Estradiol Patches - Infertility, Female, Obesity | Phase 2 | Recruiting | University of Colorado, Denver | 20 | 2025-02-25 | 2026-07-21 |
| Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study Mechanically Engineered Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes, Umbilical cord mesenchymal stem cell-derived exosomes, platelet-rich plasma - Thin Endometrial Lining, Female Infertility | Phase 1 / Phase 2 | Recruiting | Tang-Du Hospital | 90 | 2025-02-21 | 2025-03-26 |
| Supplementation for Male Subfertility Active multi-ingredient supplement (Fertility Enhancer, FE), Inactive placebo (Placebo; PLA) - Male Infertility | Phase 2 | Not yet recruiting | Hamilton Health Sciences Corporation | 64 | 2025-01-01 | 2024-10-10 |
| Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product MediReg® Medicinal product MediReg® (Human Mesenchymal Stromal Cell Secretome), lyophilizate for preparation of solution for injection in patients with severe spermatogenesis disorders, Clostilbegit (clomiphene) 50 mg 1 tablet x 1 p a day - 3 months, Triovit - 1 tablet x 1 p a day - 3 months, Folic acid - 1 tablet x 1 p a day - 3 months. - Azoospermia, Nonobstructive, Teratospermia | Phase 1 / Phase 2 | Recruiting | Lomonosov Moscow State University Medical Research and Educational Center | 80 | 2024-11-26 | 2025-03-11 |
Showing 20 of 215. Sign in to see all of them.
Infertility, Female (37) · Infertility, Male (31) · Endometriosis (12) · Obesity (8) · Oligospermia (8) · Polycystic Ovary Syndrome (8) · Asthenozoospermia (6) · Azoospermia (6) · Hypogonadism (5) · Dysmenorrhea (4) · Dyspareunia (4) · Endometrial Hyperplasia (4) · Gynatresia (4) · Pelvic Pain (4)
Genital Diseases (215) · Urogenital Diseases (215) · Female Urogenital Diseases and Pregnancy Complications (66) · Female Urogenital Diseases (63) · Genital Diseases, Female (60) · Male Urogenital Diseases (47) · Genital Diseases, Male (45) · Pathological Conditions, Signs and Symptoms (20) · Endocrine System Diseases (16) · Signs and Symptoms (16) · Gonadal Disorders (15) · Neoplasms (12) · Nutritional and Metabolic Diseases (10) · Pathologic Processes (10)
Clomiphene (14) · Chorionic Gonadotropin (10) · Sodium Chloride (9) · Gonadotropin-Releasing Hormone (8) · follitropin alfa (8) · Cabergoline (7) · Letrozole (7) · Triptorelin Pamoate (6) · follicle stimulating hormone, human, with HCG C-terminal peptide (6) · Denosumab (5) · Folic Acid (5) · Glycoprotein Hormones, alpha Subunit (5) · Luteinizing Hormone, beta Subunit (5) · Metformin (5) · cetrorelix (5)
Benha University (8) · Ferring Pharmaceuticals (7) · Cairo University (6) · Martin Blomberg Jensen (6) · Merck KGaA, Darmstadt, Germany (6) · Royan Institute (6) · Bedaya Hospital (5) · Genesis Athens Clinic (5) · National and Kapodistrian University of Athens (5) · Ain Shams University (4) · Aljazeera Hospital (4) · Assiut University (4) · Riyadh Fertility and Reproductive Health center (4) · Abbott (3) · Al-Azhar University (3)
Egypt (46) · United States (37) · Spain (14) · Denmark (13) · China (11) · Greece (11) · Canada (10) · Iran (9) · Belgium (6) · Czechia (5) · United Kingdom (5) · Italy (4) · Poland (4) · Russia (4) · Iraq (3)
Usama M Fouda, Prof. (4) · Santiago Munne, PhD (3) · Usama M Fouda, M.D, PhD (3) · Agni Pantou, MD (2) · Ahmed M Sayed, M.D, PhD (2) · David H Barad, MD, MS (2) · Dina M Dakhly, MD (2) · Hamid Gourabi, PhD (2) · Nanette Santoro, MD (2)
PMID 33851429, PMID 34792133, PMID 37699851, PMID 10548619, PMID 11228933, PMID 12516764, PMID 14561807, PMID 15126522, PMID 15579793, PMID 17197592, PMID 18281242, PMID 18343810, PMID 18675974, PMID 18678368, PMID 18783876, PMID 19381855, PMID 19729414, PMID 19910321, PMID 20031032, PMID 20149360, PMID 20672903, PMID 21575849, PMID 21693030, PMID 21703683, PMID 21714697, PMID 21806579, PMID 21853931, PMID 22081410, PMID 22197127, PMID 22459631, PMID 22464760, PMID 22740496, PMID 22748101, PMID 22877941, PMID 22895856, PMID 23106834, PMID 23292545, PMID 23341491, PMID 23357459, PMID 23431372, PMID 23518033, PMID 23757979, PMID 23900207, PMID 24097378, PMID 24424357, PMID 24695882, PMID 24812310, PMID 25036713, PMID 25256937, PMID 25274200
2015 (2), 2016 (2), 2023 (2), 2008 (1), 2018 (1), 2025 (1), K24HD082231 (1), P30CA016672 (1), P50CA090270 (1), U10CA031946 (1), U54HD028138 (1)