36 completed, 36 unknown, 14 recruiting, 5 active not recruiting. 63 Not applicable, 10 Phase 2, 9 Phase 1, 6 Phase 4, 2 Early Phase 1.
Follow Gynatresia: new trials by email Literature Review of Gynatresia trials Research Report on Gynatresia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intrauterine Stent Placement Following Hysteroscopic Septum Resection Intraoperative placement of an inflated intrauterine pediatric foley catheter, No Catheter placement, Hormonal Therapy Agent - Intrauterine Adhesion | Not applicable | Recruiting | Weill Medical College of Cornell University | 320 | 2026-05-14 | 2026-06-12 |
| Clinical Study of i-PRF Intrauterine Perfusion for Endometrial Regeneration and Repair in Moderate to Severe Intrauterine Adhesions Injectable Platelet-Rich Fibrin, Sodium Hyaluronate - Intrauterine Adhesions | Not applicable | Not yet recruiting | Beijing Obstetrics and Gynecology Hospital | 200 | 2026-05-01 | 2026-04-17 |
| Clinical Study on the Effect of Umbilical Cord Mesenchymal Stem Cell Exosomes on Endometrial Repair of Intrauterine Adhesions Exosmoes, HRT - Intrauterine Adhesions, Exosomes | Not applicable | Active not recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 60 | 2026-01-01 | 2026-02-18 |
| CURENDO (Cord-blood Uterine Regeneration Endometrium): Platelet-rich Plasma Therapy Derived From Umbilical Cord Blood for the Treatment of Endometrial Pathologies (Asherman Syndrome / Endometrial Atrophy / Thin Endometrium) Umbilical cord platelet-rich plasma (hUC-PRP) - Asherman Syndrome | Not applicable | Recruiting | Fundación IVI | 35 | 2025-12-18 | 2026-07-13 |
| Incidence of Intrauterine Adhesions After Myomectomy With Intrauterine Anti-Adhesion Gel Women will receive the application of an anti-adhesion gel at the end of the myomectomy procedure - Myoma;Uterus, Adhesion; Uterus, Internal | Not applicable | Not yet recruiting | Federico II University | 62 | 2025-12-09 | 2025-12-12 |
| AD-SVF Therapy for Refractory Endometrial Infertility AD-SVF - Endometrium; Atrophy, Intrauterine Synechiae | Phase 1 | Recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 10 | 2025-11-01 | 2025-11-18 |
| Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion Intrauterine Abnormalities in Infertility, Asherman Syndrome | Not yet recruiting | Semikal Technology | 80 | 2025-11-01 | 2025-09-08 | |
| hBMSC Uterine Artery Infusion for Severe IUA-Related Infertility Delivering human bone marrow mesenchymal stem cells via the uterine artery - Intrauterine Adhesions | Not applicable | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 60 | 2025-09-30 | 2025-09-16 |
| Comparison of Surgical Management of Early Pregnancy Loss by Suction Curettage Versus Hysteroscopy in Patients Undergoing In-vitro Fertilization (IVF) Operative hysteroscopy using tissue removal device, suction curettage - Early Abortion, Pregnancy Loss, Early | Not applicable | Recruiting | Assaf-Harofeh Medical Center | 50 | 2025-08-20 | 2026-01-27 |
| Use of Nitrous Oxide During Office Hysteroscopy Inhalation of Nitrous Oxide (N₂O) during Office Operative Hysteroscopy, inhalation of ambient air during office hysteroscopy - Abnormal Uterine Bleeding, Postmenopausal Bleeding | Not applicable | Active not recruiting | Maaynei Hayesha Medical Center | 400 | 2025-07-01 | 2025-07-20 |
| Study on the Effective Dose and Safety of Esketamine in Hysteroscopic Surgery Under Monitored Anesthesia Care Determine the ED50 and ED95 of esketamine, Intravenous the dose of esketamine ED95, Intravenous remifentanil 1μg∙kg-1 - Intrauterine Polyp, Intrauterine Synechiae | Phase 1 / Phase 2 | Active not recruiting | The First Affiliated Hospital of Xiamen University | 95 | 2025-06-26 | 2025-07-24 |
| Evaluation of the Uterine Cavity After Operative Hysteroscopy Infertility, Abnormal Uterine Bleeding (AUB) | Completed | Sohag University | 50 | 2025-03-31 | 2026-07-14 | |
| Investigating the Association Between Diagnostic and Therapeutic Management Models and Prognosis of Intrauterine Adhesions Based on a Large-Scale Prospective Cohort Study Transcervical resection of adhesion, Uterine cavity stent, Traditional Chinese medicine for tonifying the kidney - Intrauterine Adhesion | Not applicable | Recruiting | The Third Xiangya Hospital of Central South University | 5000 | 2025-03-01 | 2026-02-19 |
| Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study Mechanically Engineered Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes, Umbilical cord mesenchymal stem cell-derived exosomes, platelet-rich plasma - Thin Endometrial Lining, Female Infertility | Phase 1 / Phase 2 | Recruiting | Tang-Du Hospital | 90 | 2025-02-21 | 2025-03-26 |
| Application of Platelet-rich Plasma (PRP) in Reproductive Medicine Platelet-Rich Plasma (PRP) Injections - Premature Ovarian Insufficiency, Intrauterine Adhesion | Not applicable | Recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 300 | 2024-10-17 | 2025-02-18 |
| Senescent Endometrial Cells in Patients with Thin Endometrial Lining Endometrial Biopsy - Asherman's Syndrome, Thin Endometrial Lining | Recruiting | Trio Fertility | 100 | 2024-09-11 | 2024-11-21 | |
| Study on the Effect of Combined Estrogen and Progestogen Therapy on Endometrial Repair After Induced Abortion 17β-estradiol/dydrogesterone tablets - Pregnancy Complications | Phase 1 | Unknown | Women's Hospital School Of Medicine Zhejiang University | 200 | 2024-05-09 | 2025-08-28 |
| Operative Hysteroscopy Versus Suction Curettage for Surgical Termination of Early Pregnancy Loss (Miscarriage) Operative hysteroscopy (by tissue removal device), Suction curettage - Early Pregnancy Loss, Intrauterine Adhesion | Not applicable | Active not recruiting | Assaf-Harofeh Medical Center | 100 | 2024-04-01 | 2026-01-27 |
| Prospective Clinical Study of Nintedanib to Inhibit Endometrial Fibrosis to Prevent Recurrence of Uterine Adhesions Nintedanib 100 MG [Ofev], Nintedanib 150 MG [Ofev] - Uterine Adhesions | Phase 2 / Phase 3 | Unknown | Sixth Affiliated Hospital, Sun Yat-sen University | 90 | 2023-12-01 | 2022-12-02 |
| Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium Plerixafor - Asherman Syndrome, Atrophic Endometrium | Early Phase 1 | Recruiting | Hugh Taylor | 90 | 2023-11-01 | 2025-11-12 |
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Infertility (7) · Tissue Adhesions (7) · Abortion, Spontaneous (4) · Infertility, Female (4) · Septate Uterus (4) · Myofibroma (3) · Abortion, Missed (2) · Atrophy (2) · Cicatrix (2) · Leiomyoma (2) · Metrorrhagia (2) · Myoma (2) · Agnosia (1) · Anxiety Disorders (1)
Female Urogenital Diseases (98) · Female Urogenital Diseases and Pregnancy Complications (98) · Genital Diseases (98) · Genital Diseases, Female (98) · Urogenital Diseases (98) · Pathological Conditions, Signs and Symptoms (15) · Pathologic Processes (12) · Fibrosis (9) · Cicatrix (7) · Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms, Connective and Soft Tissue (6) · Pregnancy Complications (5) · Uterine Diseases (5) · Infertility (4)
Hysteroscopy (5) · Dydrogesterone (3) · Estradiol (3) · Saline Solution (3) · Filgrastim (2) · Granulocyte Colony-Stimulating Factor (2) · Hormone Replacement Therapy (2) · Hyaluronic Acid (2) · Sodium Chloride (2) · Vacuum Curettage (2) · femoston (2) · Anti-Bacterial Agents (1) · Aspirin (1) · Conization (1) · Dexmedetomidine (1)
Fu Xing Hospital, Capital Medical University (10) · Beijing Obstetrics and Gynecology Hospital (6) · First Affiliated Hospital, Sun Yat-Sen University (5) · Assaf-Harofeh Medical Center (4) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (4) · Fundación IVI (3) · Sixth Affiliated Hospital, Sun Yat-sen University (3) · Rejoni Inc. (2) · Sir Run Run Shaw Hospital (2) · The Fourth Affiliated Hospital of Zhejiang University School of Medicine (2) · The Third Xiangya Hospital of Central South University (2) · University Hospital, Ghent (2) · Weill Medical College of Cornell University (2) · Womed (2) · Women's Hospital School Of Medicine Zhejiang University (2)
China (44) · Israel (8) · United States (7) · Spain (6) · Belgium (4) · Egypt (4) · France (3) · Netherlands (3) · Czechia (2) · Italy (2) · Taiwan (2) · Turkey (Türkiye) (2) · Belarus (1) · Bulgaria (1) · Canada (1)
Tinchiu Li (4) · Duan Hua, PhD (3) · Limin Feng (2) · Noam Smorgick, MD (2) · Shuzhong Yao, professor (2) · Yali HU, MD,PhD (2) · Alexandr Gzgzyan, Prof, PhD (1) · Andrea Tinelli (1) · Byeongseok Lee, MD (1) · Carlos Simon, MD, PhD (1) · Chanyu Zhang (1) · Cindy Basinski, MD (1) · David H Barad, MD, MS (1)
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