Glycoprotein Hormones, alpha Subunit: Clinical Trials

47 trials of Glycoprotein Hormones, alpha Subunit, newest first

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33 completed, 7 terminated, 5 unknown, 2 recruiting. 17 Phase 4, 10 Phase 3, 7 Phase 2, 4 Not applicable, 3 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 417Completed 11, Terminated 3, Unknown 3
Phase 310Completed 10
Phase 27Completed 4, Terminated 2, Recruiting 1
Not applicable4Completed 2, Recruiting 1, Unknown 1
Phase 13Completed 3

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation
Biospecimen Collection, Cobimetinib, Computed Tomography - Thyroid Gland Follicular Carcinoma, Thyroid Gland Oncocytic Carcinoma
Phase 2RecruitingCity of Hope Medical Center212024-07-152026-02-02
Extra Luteinizing Hormone Improve Embryo Quality in IVF Patients With Low LH During Long GnRH-Agonist Treatment
Recombinant Luteinizing Hormone (rLH), Recombinant Follicle-Stimulating Hormone (rFSH), Gonadotropin-Releasing Hormone Agonist (GnRH-a) - Infertility, Female, Luteinizing Hormone (LH)
Not applicableRecruitingNanjing University5902024-02-012025-08-19
Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells
Follitropin beta injection 150 IU, Follitropin beta injection 300 IU - Ovarian Function Insufficiency, Fertility Issues
Phase 1CompletedART Fertility Clinics LLC62023-07-052025-01-09
Comparison of Recombinant Follicle Stimulating Hormone and the Combination of Recombinant Follicle Stimulating Hormone With Clomiphene Citrate in Stimulated Intrauterine Insemination Cycles
Recombinant Follicle Stimulating Hormone, Recombinant Follicle Stimulating Hormone and Clomiphene Citrate - Infertility Unexplained
Not applicableUnknownBezmialem Vakif University2542023-01-012024-02-02
Estradiol and Progesterone Levels Following Frozen Embryo Transfer
Estradiol Tablets, Progesterone, Follitropin Alfa - Infertility
Phase 4CompletedCopenhagen University Hospital at Herlev3052021-04-202025-01-03
Ovarian Response to Recombinant Follicle Stimulating Hormone in Women With PCOS
Recombinant Follicle Stimulating Hormone - Polycystic Ovary Syndrome, Healthy
Phase 4CompletedUniversity of California, San Diego332017-10-022021-09-08
Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI
Triptorelin, cetrorelix, Recombinant Follicle Stimulating Hormone - Invitro Fertilization
Phase 4CompletedCairo University2042017-04-212017-11-07
Hormone Evaluation in Artificial Reproductive Technology
Follitropin alpha, Menotropin - Female Infertility
Not applicableCompletedLund University8102016-09-012025-03-17
Efficacy of Urinary Vs Recombinant FSH in Oocyte Donors Based on Receptor N680S FSH Gene Polymorphism (Genodon Trial)
Urinary follicle-stimulating hormone, Recombinant follicle-stimulating hormone - Reproductive Techniques, Assisted
Phase 4UnknownInstituto Bernabeu1802015-12-012018-08-28
The Safety and Pharmacokinetics of Primapur and Gonal-f
Follitropin alfa (Primapur), Follitropin alfa (Gonal-F) - Area Under Curve, Pharmacokinetics
Phase 1CompletedIVFarma LLC282015-10-292019-08-13
Efficacy of Recombinant FSH/GnRH Antagonist Protocol With and Without LH Adjunct for Egg Bank Donation
Follistim, Ganirelix, Menotropins - Egg Donation
Phase 4CompletedMichigan Reproductive Medicine382014-04-012018-03-23
FSH in GnRH-AntagoniST Controlled Ovarian Hyperstimulation Cycles (FAST)
Urofollitrophin, Follitrophin alpha - Infertility
Phase 4CompletedIBSA Institut Biochimique SA7102014-01-012019-10-09
Phase III Study Comparing Efficacy and Safety of AFOLIA vs Gonal-f® RFF in Women (35 to 42) Undergoing IVF
AFOLIA, Gonal-f® RFF - Infertility
Phase 3CompletedFertility Biotech AG11002013-11-252017-12-05
Low-dose Gonal-f® in Ovulation Induction
Gonal-f® - Infertility, Monofollicular Development
Phase 4TerminatedMerck KGaA, Darmstadt, Germany242013-07-012016-08-11
Assessment of Implantation Potential of Embryos by Time-lapse Technology
recombinant Follicle Stimulating Hormone (rFSH) - Embryo/Fetus Death, Blastocyst Disintegration
Phase 4UnknownBloom IVF and Fertility Centre2002012-12-012013-01-04
Predicting Ovarian Response in Artificial Insemination With Low Stimulation
Follicle Stimulating Hormone - Subfertility
UnknownIsala5102012-12-012012-12-13
Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism
Lutropin alfa, Follitropin alfa and Lutropin alfa - Infertility
Phase 4UnknownRoyan Institute902012-11-012015-05-06
Efficacy of Pergoveris in Aged IVF Patients
Pergoveris (FSH and LH), Follitropin alpha (FSH) - Infertility
Not applicableCompletedVietnam National University2402012-10-012014-12-25
Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women
MSJ-0011, urinary hCG (u-hCG), Follitropin alpha - Anovulation, Oligo-ovulation
Phase 3CompletedMerck KGaA, Darmstadt, Germany812012-09-012016-01-07
A Dose-response Trial Using rFSH FE 999049 in Women Undergoing IVF/ICSI Treatment
FE 999049, Gonal - F - Infertility
Phase 2CompletedFerring Pharmaceuticals2652011-09-012020-11-17

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Conditions studied

Infertility (26)  ·  Helping Behavior (5)  ·  Polycystic Ovary Syndrome (4)  ·  Infertility, Female (3)  ·  Ovarian Hyperstimulation Syndrome (3)  ·  Anovulation (2)  ·  Congenital Abnormalities (2)  ·  Hypogonadism (2)  ·  Adenocarcinoma, Follicular (1)  ·  Aneuploidy (1)  ·  Embryo Loss (1)  ·  Hyperandrogenism (1)  ·  Infertility, Male (1)  ·  Stillbirth (1)  ·  Thyroid Cancer, Papillary (1)

Sponsors

Merck KGaA, Darmstadt, Germany (16)  ·  Organon and Co (5)  ·  Ferring Pharmaceuticals (3)  ·  EMD Serono (2)  ·  ART Fertility Clinics LLC (1)  ·  Azienda USL Modena (1)  ·  Bezmialem Vakif University (1)  ·  Bloom IVF and Fertility Centre (1)  ·  Cairo University (1)  ·  City of Hope Medical Center (1)  ·  Copenhagen University Hospital at Herlev (1)  ·  Copenhagen University Hospital, Rigshospitalet (1)  ·  Fertility Biotech AG (1)  ·  IBSA Institut Biochimique SA (1)  ·  IVFarma LLC (1)

Countries

Spain (8)  ·  United States (5)  ·  Belgium (4)  ·  Denmark (4)  ·  Germany (4)  ·  France (3)  ·  Turkey (Türkiye) (3)  ·  China (2)  ·  Czechia (2)  ·  Greece (2)  ·  Italy (2)  ·  Poland (2)  ·  Sweden (2)  ·  Switzerland (2)  ·  United Kingdom (2)

Top investigators

Ahmed Maged, MD (1)  ·  Anders N Andersen, professor (1)  ·  Barbara Lawrenz, PhD (1)  ·  Ben Cohlen, dr. (1)  ·  Christophe Blockeel, MD (1)  ·  Dr. Enrique Granados (1)  ·  Eduardo Kelly, MD, MBA (1)  ·  Hamid Gourabi, PhD (1)  ·  Hrishikesh D Pai, M.D. (1)  ·  Ivan G Gordeev, D.Sc., MD (1)

Results publications

PMID 22587997, PMID 26950065, PMID 26991902, PMID 18024487, PMID 18583332, PMID 18765009, PMID 19684043, PMID 20031032, PMID 20483664, PMID 20843746, PMID 21575849, PMID 21575853, PMID 22244781, PMID 23394782, PMID 23758821, PMID 24903202, PMID 24942155, PMID 25256937, PMID 25596910, PMID 25740882, PMID 27619773, PMID 28508691, PMID 32819842, PMID 35460412

NIH funding

2004 (1), 2005 (1), 2008 (1), 2015 (1), K12HD001259 (1), P30CA033572 (1), P50HD012303 (1)