21 completed, 4 unknown, 2 not yet recruiting, 2 recruiting. 20 Not applicable, 5 Phase 4, 2 Phase 1, 1 Phase 2, 1 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cl-Pharm-IBS-ML-2026 Questionnaire and Physical Exam - IBS | Not yet recruiting | Tanta University | 500 | 2026-09-20 | 2026-09-11 | |
| Effect of Multispecies Probiotic Supplementation on the Efficacy of Rifaximin α Therapy in Patients With Small Intestinal Bacterial Overgrowth (SIBO): a Randomized Placebo-controlled Trial Probiotic preparation, Placebo, Rifaximin (drug) - Small Intestinal Bacterial Overgrowth Syndrome (SIBO), IBS | Phase 4 | Not yet recruiting | Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji | 100 | 2026-02-15 | 2026-02-23 |
| Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD Experimental: Case Group - Tomato-free diet, Experimental: Case group - Diet enriched with tomatoes - NAFLD, IBS | Not applicable | Completed | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | 80 | 2024-05-14 | 2026-04-16 |
| Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters. Mediterranean diet and moderate intensity physical exercise (outdoor walking). - NAFLD, Obesity | Not applicable | Completed | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | 36 | 2024-03-19 | 2026-04-20 |
| Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation Tenapanor - IBS, IBS - Irritable Bowel Syndrome | Phase 4 | Completed | Kyle Staller, MD, MPH | 36 | 2024-02-06 | 2026-03-12 |
| The Living With a Long-Term Condition Study Living with LTC Questionnaire - Asthma, Atrial Fibrillation | Unknown | King's College London | 600 | 2023-06-28 | 2023-10-12 | |
| Comparison of the Atmo Motility Gas Capsule System to the Reference Standard Atmo Motility Gas Capsule System, SmartPill Monitoring System - Gastroparesis, Slow Transit Constipation | Not applicable | Unknown | Atmo Biosciences Pty Ltd | 209 | 2023-06-05 | 2024-01-10 |
| Ebastine Versus Mebeverine in IBS Patients Ebastine, Duspatalin - IBS - Irritable Bowel Syndrome, IBS | Phase 3 | Active not recruiting | Guy Boeckxstaens | 200 | 2023-03-30 | 2026-09-11 |
| Gabapral in Pediatric IBS Gabapral, Placebo - Bifidobacterium Adolescentis PRL2019, IBS | Not applicable | Unknown | Azienda Ospedaliera "Sant'Andrea" | 20 | 2023-03-01 | 2023-02-21 |
| Efficacy of a Low FODMAP Diet in IBS Children and Impact on Urinary and Faecal Metabolome LOW FODMAPs Diet - IBS, Functional Gastrointestinal Disorders | Not applicable | Completed | University of Bari | 70 | 2023-01-01 | 2026-02-09 |
| Systems Biology of Gastrointestinal and Related Diseases Ulcerative Colitis, Crohn Disease | Terminated | Viome | 17 | 2022-11-11 | 2023-12-15 | |
| Optimization of Transcutaneous Electrical Acustimulation (TEA) Modalities for Treatment of IBS-C Transcutaneous Electrical Acustimulation (TEA) - IBS, Constipation | Not applicable | Completed | University of Michigan | 23 | 2021-07-01 | 2024-02-16 |
| Health Effects of Different Types of Bread Intervention group - IBS | Not applicable | Completed | Oslo Metropolitan University | 20 | 2020-09-01 | 2021-05-12 |
| The Effect of Two Probiotic Products on the Intestinal Barrier Function in Patients With Irritable Bowel Syndrome Probiotics, Placebo - IBS | Not applicable | Completed | Örebro University, Sweden | 65 | 2019-03-26 | 2021-09-09 |
| A Study of Probiotics in IBS Subjects Probiotic 1, Probiotic 2, Placebo - IBS | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 336 | 2018-03-30 | 2019-07-05 |
| Mindfulness-Based Eating in Patients With Irritable Bowel Syndrome Dietary intervention, Irritable Bowel Syndrome eating awareness training - Abdominal Pain, Irritable Bowel Syndrome | Not applicable | Completed | University of Miami | 20 | 2017-07-01 | 2018-06-12 |
| Fecal Metabolome and the Intestinal Microbiota in Irritable Bowel Syndrome X-Ray - IBS | Completed | Indiana University | 100 | 2016-07-01 | 2024-04-29 | |
| Just in TIME - Intervention With Dance and Yoga for Girls With Recurrent Abdominal Pain Dance and yoga intervention - Functional Abdominal Pain, IBS | Not applicable | Completed | Anna Duberg | 121 | 2016-04-01 | 2025-04-06 |
| Analyzing IBS to Identify Biomarkers and Microbiome Signatures endoscopy for tissue biopsy, Blood Sample, Stool Sample - Diarrhoea Predominant Irritable Bowel Syndrome, IBS | Not applicable | Completed | Mayo Clinic | 26 | 2015-05-01 | 2017-07-07 |
| Integrative Approaches to Managing Irritable Bowel Syndrome (IBS) Nutrition/Mind-Body Coaching - Irritable Bowel Syndrome, IBS | Not applicable | Completed | Beth Israel Medical Center | 52 | 2015-04-01 | 2018-02-14 |
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Irritable Bowel Syndrome (6) · Non-alcoholic Fatty Liver Disease (3) · Obesity (3) · Abdominal Pain (2) · Celiac Disease (2) · Colitis, Ulcerative (2) · Constipation (2) · Crohn Disease (2) · Diarrhea (2) · Gastrointestinal Diseases (2) · Liver Diseases (2) · Motor Activity (2) · Acquired Immunodeficiency Syndrome (1) · Amyotrophic Lateral Sclerosis (1) · Anemia, Sickle Cell (1)
Digestive System Diseases (13) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (10) · Gastrointestinal Diseases (9) · Intestinal Diseases (9) · Colonic Diseases (8) · Colonic Diseases, Functional (6) · Signs and Symptoms, Digestive (6) · Behavior (4) · Neurologic Manifestations (4) · Body Weight (3) · Fatty Liver (3) · Immune System Diseases (3) · Nutrition Disorders (3) · Nutritional and Metabolic Diseases (3)
FODMAP Diet (3) · Probiotics (2) · Rifaximin (2) · maltodextrin (2) · Blood Specimen Collection (1) · Diet Therapy (1) · Diet, Mediterranean (1) · Drug Delivery Systems (1) · Endoscopy (1) · Fentanyl (1) · Lacteol (1) · Mexiletine (1) · Midazolam (1) · Pharmaceutical Preparations (1) · Propofol (1)
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis (2) · KU Leuven (2) · Mayo Clinic (2) · Tel-Aviv Sourasky Medical Center (2) · Anna Duberg (1) · Atmo Biosciences Pty Ltd (1) · Azienda Ospedaliera "Sant'Andrea" (1) · Beth Israel Deaconess Medical Center (1) · Beth Israel Medical Center (1) · Bezmialem Vakif University (1) · Guy Boeckxstaens (1) · Indiana University (1) · King's College London (1) · Kyle Staller, MD, MPH (1) · Medical University of Vienna (1)
United States (11) · Belgium (3) · Italy (3) · Germany (2) · Israel (2) · Sweden (2) · Austria (1) · Canada (1) · India (1) · Norway (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Guy Boeckxstaens, MD (2) · Ami Sperber, MD (1) · Amy Foxx-Orenstein, DO (1) · Anantha Padmanabhan, MD (1) · Andrea Shin, MD (1) · Anna Duberg, PhD (1) · Annette Fritscher-Ravens, MD, PhD (1) · Annie Jones, PhD (1) · Anthony Lembo, MD (1) · Braden Kuo, MD (1) · Daniel Sussman, MD (1) · Elizabeth McDonald, MS,RD,CSS (1) · Emma Jenkinson, MSc (1) · Gabriele Moser, MD, Prof (1) · Guy Boeckxstaens, prof. dr. (1)
PMID 15862938, PMID 16051399, PMID 18524691, PMID 20170751, PMID 24613995, PMID 25016597, PMID 26855665, PMID 27144632, PMID 28483500, PMID 28625832, PMID 29154390, PMID 30095672, PMID 33320103, PMID 34529293, PMID 36227781, PMID 36364888, PMID 36646863, PMID 37152307, PMID 39485760, PMID 39889900, PMID 41273450, PMID 42124549, PMID 42494249
1UG3NS115108-01A1 (1), R03DK067878 (1)