7 withdrawn. 7 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Withdrawn 7 |
| Phase 2 | 2 | Withdrawn 2 |
Follow Hypoxia: new trials by email Literature Review of Hypoxia trials Research Report on Hypoxia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia Caffeine citrate - Acute Kidney Injury, Hypoxic-Ischemic Encephalopathy | Phase 1 | Withdrawn | University of Arkansas | 2024-05-08 | 2024-05-10 | |
| Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation L-NMMA, Ketorolac, Ascorbic Acid - Hypoxia, Hypercapnia | Phase 1 | Withdrawn | University of Wisconsin, Madison | 2020-12-01 | 2019-01-10 | |
| Frespaciguat (MK-5475) in Participants With Hypoxemia Due to COVID-19 Pneumonia (MK-5475-009) Frespaciguat, Placebo - Coronavirus Disease 2019 (COVID-19), Pneumonia | Phase 1 | Withdrawn | Merck Sharp & Dohme LLC | 2020-07-07 | 2025-05-15 | |
| Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy Autologous cord blood, Hypothermia - Hypoxic Ischemic Encephalopathy, Cerebral Infarction | Phase 1 / Phase 2 | Withdrawn | Children's Hospital of Fudan University | 2015-09-08 | 2023-12-29 | |
| Melatonin Treatment for Newborn Infants With Moderate to Severe Hypoxic Ischemic Encephalopathy Melatonin, placebo - Newborn Hypoxic Ischemic Encephalopathy | Phase 1 | Withdrawn | St. Louis University | 2014-04-01 | 2015-07-03 | |
| Clinical Study of the Efficacy and Safety of the Application of Allogeneic Mesenchymal (Stromal) Cells of Bone Marrow, Cultured Under the Hypoxia in the Treatment of Patients With Severe Pulmonary Emphysema Mesenchymal stem cells, Reference therapy: 400 mL of 0.9% NaCl solution - Pulmonary Emphysema | Phase 1 / Phase 2 | Withdrawn | Federal Research Clinical Center of Federal Medical & Biological Agency, Russia | 2014-03-01 | 2018-01-09 | |
| Effects of Iloprost on Hypoxic Pulmonary Vasoconstriction at Altitude iloprost - Hypoxic Pulmonary Vasoconstriction | Phase 1 | Withdrawn | Loma Linda University | 2008-07-01 | 2015-09-18 |
Hypoxia-Ischemia, Brain (3) · Acute Kidney Injury (1) · COVID-19 (1) · Cerebral Infarction (1) · Emphysema (1) · Hypercapnia (1) · Pneumonia (1) · Pulmonary Emphysema (1)
Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Signs and Symptoms, Respiratory (7) · Brain Diseases (3) · Brain Ischemia (3) · Cardiovascular Diseases (3) · Central Nervous System Diseases (3) · Cerebrovascular Disorders (3) · Hypoxia, Brain (3) · Nervous System Diseases (3) · Vascular Diseases (3) · Lung Diseases (2) · Pathologic Processes (2) · Respiratory Tract Diseases (2)
Ascorbic Acid (1) · High-Energy Shock Waves (1) · Iloprost (1) · Ketorolac (1) · Melatonin (1) · Ultrasonography, Doppler, Transcranial (1) · caffeine citrate (1) · omega-N-Methylarginine (1)
Children's Hospital of Fudan University (1) · Federal Research Clinical Center of Federal Medical & Biological Agency, Russia (1) · Loma Linda University (1) · Merck Sharp & Dohme LLC (1) · St. Louis University (1) · University of Arkansas (1) · University of Wisconsin, Madison (1)
United States (4) · China (1) · Russia (1)
Alexander V Averyanov, MD, PhD (1) · Farouk Sadiq, MD (1) · James Anholm, MD (1) · Jennifer Rumpel, MD (1) · Katja Ruh, MD (1) · Wenhao Zhou, Doctor (1) · William G Schrage, PhD (1)