14 terminated. 14 Phase 2, 5 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Terminated 14 |
| Phase 3 | 5 | Terminated 5 |
| Phase 1 | 3 | Terminated 3 |
Follow Hypoglycemia: new trials by email Literature Review of Hypoglycemia trials Research Report on Hypoglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Administration of Insulin Glargine in Patients With Diabetic Ketoacidosis Insulin Glargine - DKA | Phase 2 | Terminated | HealthPartners Institute | 8 | 2022-05-31 | 2024-06-18 |
| Dapagliflozin During Exercise for the PrevenTion of Hypoglycaemia Dapagliflozin 10 MG Oral Tablet - Diabetes Mellitus, Type 1 | Phase 2 | Terminated | University of Oxford | 9 | 2018-06-02 | 2022-05-18 |
| Propranolol in Treating Hypoglycemia Unawareness Propranolol 80 Mg Oral Capsule, Extended Release, Placebo oral capsule - Type 1 Diabetes Mellitus | Phase 2 | Terminated | Anu Sharma | 2 | 2017-10-19 | 2020-08-24 |
| Intra-nasal Naloxone for Treatment of Impaired Awareness of Hypoglycemia intra-nasal naloxone, Intra-nasal saline - Hypoglycemia Unawareness, Type 1 Diabetes | Phase 1 / Phase 2 | Terminated | University of Minnesota | 11 | 2016-06-01 | 2023-03-27 |
| Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia Exendin (9-39), Vehicle - Congenital Hyperinsulinism | Phase 1 / Phase 2 | Terminated | Diva De Leon | 14 | 2009-08-26 | 2020-06-01 |
| The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients Glucagon-Like Peptide-1, Saline - Critically Ill, Hypoglycemia | Phase 2 | Terminated | Johns Hopkins University | 19 | 2008-12-01 | 2017-07-02 |
| Mechanisms of Hypoglycemia Associated Autonomic Failure naloxone, fructose, exercise - Diabetes Mellitus, Hypoglycemia | Phase 2 | Terminated | Albert Einstein College of Medicine | 39 | 2008-03-01 | 2026-05-19 |
| Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes Allogeneic islets of Langerhans transplant, Raptiva, Sirolimus - Type 1 Diabetes Mellitus, Hypoglycemia | Phase 1 / Phase 2 | Terminated | University of Minnesota | 23 | 2007-11-01 | 2017-10-25 |
| B-Lymphocyte Immunotherapy in Islet Transplantation Allogeneic Pancreatic Islet Cells, Antithymocyte globulin, Daclizumab - Type 1 Diabetes Mellitus | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 2 | 2006-11-01 | 2016-03-21 |
| Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy in Patients With Types 1 and 2 Diabetes Mellitus Pulsatile IV Insulin, Effects of Pulsatile IV Insulin on Diabetic Retinopathy - Diabetes Mellitus, With Complications | Phase 2 / Phase 3 | Terminated | Florida Atlantic University | 150 | 2005-11-01 | 2016-08-10 |
| Effect of Pulsatile IV Insulin on Circulating Risk Markers of Vascular and Metabolic Complications in Pts With Diabetes Effect of Pulsatile IV insulin on diabetic pt blood markers, Effect of Pulsatile IV Insulin on blood markers - Diabetes Mellitus | Phase 2 / Phase 3 | Terminated | Florida Atlantic University | 105 | 2005-02-01 | 2016-08-09 |
| Effects of Pulsatile Insulin Delivery on Diabetic Neuropathy in Patients With Types 1 and 2 Diabetes Mellitus Effect of Pulsatile IV insulin on diabetic neuropathy, Effect of Pulsatile IV Insulin on diabetic neuropathy - Diabetes Mellitus, With Complications | Phase 2 / Phase 3 | Terminated | Florida Atlantic University | 152 | 2004-02-01 | 2016-08-10 |
| Clinical Effects of Pulsatile Insulin Delivery on Cognitive Function- Phase 1 Pulsatile IV insulin therapy, Effects of Pulsatile IV Insulin on Cognitive functions - Diabetes Mellitus | Phase 2 / Phase 3 | Terminated | Florida Atlantic University | 75 | 2003-06-01 | 2016-08-10 |
| Effect Pulsatile IV Insulin Therapy on the Quality of Life in Patients With Types 1 and 2 Diabetes Effects of Pulsatile IV insulin on Diabetic Quality of Life - Diabetes Mellitus | Phase 2 / Phase 3 | Terminated | Florida Atlantic University | 152 | 2003-03-01 | 2016-08-10 |
Diabetes Mellitus (6) · Diabetes Mellitus, Type 1 (6) · Diabetes Complications (5) · Congenital Hyperinsulinism (1) · Critical Illness (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Neuropathies (1) · Glucose Metabolism Disorders (1) · Hyperinsulinism (1) · Infant, Newborn, Diseases (1) · Metabolic Diseases (1) · Motor Activity (1) · Pancreatic Diseases (1) · Pure Autonomic Failure (1)
Nutritional and Metabolic Diseases (14) · Glucose Metabolism Disorders (13) · Metabolic Diseases (13) · Endocrine System Diseases (12) · Autoimmune Diseases (6) · Diabetes Mellitus (6) · Immune System Diseases (6) · Nervous System Diseases (2) · Autonomic Nervous System Diseases (1) · Behavior (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Diseases (1) · Disease Attributes (1) · Neuromuscular Diseases (1) · Pathologic Processes (1)
Insulin Aspart (5) · Insulin, Regular, Human (4) · Antilymphocyte Serum (2) · Naloxone (2) · Sirolimus (2) · Capsules (1) · Daclizumab (1) · Epinephrine (1) · Exercise (1) · Fructose (1) · Glucagon-Like Peptide 1 (1) · Insulin (1) · Insulin Glargine (1) · Morphine (1) · Propranolol (1)
Florida Atlantic University (5) · University of Minnesota (2) · Albert Einstein College of Medicine (1) · Anu Sharma (1) · Diva De Leon (1) · HealthPartners Institute (1) · Johns Hopkins University (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · University of Oxford (1)
United States (13) · United Kingdom (1)
Betty Tuller, Ph.D (3) · Adis Keric, PharmD (1) · Ali Naji, MD, PhD (1) · Amir Moheet, MD (1) · Anu Sharma, MD (1) · Bernhard J. Hering, M.D. (1) · Betty Tuller, Ph.D. (1) · Betty Tuller, PhD (1) · Dariush Elahi, PhD (1) · Diva D De Leon, MD MSCE (1) · Ioannis Spiliotis, MD (1) · Meredith Hawkins, M.D., M.S. (1)
2017 (1), R01DK079974 (1)