21 completed, 8 unknown, 3 recruiting, 3 terminated. 7 Phase 4, 4 Phase 1, 4 Phase 2, 4 Phase 3, 3 Not applicable.
Follow Hyperprolactinemia: new trials by email Literature Review of Hyperprolactinemia trials Research Report on Hyperprolactinemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Potency of a High Cabergoline Dosage in Microprolactinomas Cabergoline - Prolactinoma, Prolactin Excess | Phase 3 | Recruiting | University of Sao Paulo General Hospital | 70 | 2026-03-04 | 2026-03-13 |
| Metabolic Outcomes in Patients With Prolactinomas Under Dopamine Agonist Treatment Cabergoline (Dopamine Agonist) - Prolactinoma | Phase 4 | Recruiting | University Hospital, Basel, Switzerland | 60 | 2025-09-16 | 2025-09-23 |
| A Phase III Clinical Study of Cabergoline Tablets Compared With Bromocriptine Mesylate Tablets Cabergoline tablets, Bromocriptine mesylate tablets - Hyperprolactinemia | Phase 3 | Recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 382 | 2025-09-12 | 2025-10-02 |
| A Study on Bioequivalence of Cabergoline Tablets in Human Body Cabergoline tablets test formulation, Cabergoline tablets reference formulation - Hyperprolactinemia | Phase 1 | Active not recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 72 | 2025-06-30 | 2025-11-17 |
| Impact of Helicobacter Pylori Infection on Prolactin Levels in Reproductive-Age Women to Determine Whether H. Pylori Infection is Associated with Elevated Prolactin Levels and Assess the Clinical Implications HELICOBACTER PYLORI INFECTIONS, Hyperprolactinaemia | Not yet recruiting | Assiut University | 75 | 2025-06-01 | 2025-03-11 | |
| Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients antipsychotic drugs inducing hyperprolactinemia - Schizophrenia Spectrum and Other Psychotic Disorders, Periodontal Diseases | Completed | Fayoum University | 64 | 2022-09-01 | 2023-09-18 | |
| PROSA: Prolactin, Sex Hormones, Growth and Metabolic Biomarkers in Children and Adolescents on Antipsychotics Hyperprolactinemia, Puberty Disorders | Completed | Ulla Schierup Nielsen | 90 | 2021-11-01 | 2026-04-30 | |
| Hyperprolactinemia and Adrenal Steroidogenesis Hyperprolactinemia | Terminated | Insel Gruppe AG, University Hospital Bern | 5 | 2021-06-24 | 2023-12-06 | |
| Prevalence of Hyperprolactinemia in Systemic Scleroderma blood test - Sclerosis, Systemic, Scleroderma | Completed | University Hospital, Lille | 71 | 2021-03-01 | 2025-12-23 | |
| Clinical Guidance for Proper Treatment of Unexplained Resistant Hyperprolactinemia. cabergoline 1.5-2 mg/week).orally daily for 1 month plus health education, cabergoline 1.5-2 mg/week).orally daily for 1 month without health education - Health Education | Phase 1 | Completed | Woman's Health University Hospital, Egypt | 120 | 2020-02-01 | 2023-05-25 |
| Prolactin Change in Chinese Patients With Schizophrenia After Antipsychotics Treatment Antipsychotic - Schizophrenia, Antipyretics Toxicity | Completed | Shanghai Mental Health Center | 10363 | 2019-06-06 | 2022-10-27 | |
| Effectiveness and Safety of Bushen Culuan Decoction for Anovulatory Infertility experimental group: Bushen Culuan Decoction and Clomiphene Citrate Tablets placebo, control group: Clomiphene Citrate Tablets and Bushen Culuan Decoction placebo - Anovulatory Infertility, Abnormal Uterine Bleeding-Ovulatory Disorders | Phase 2 | Unknown | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 528 | 2019-02-01 | 2019-01-10 |
| Effects of Hyperprolactinemia Induced by Antipsychotic Drugs on Bone Metabolism Schizophrenia | Unknown | Shanghai Mental Health Center | 120 | 2018-07-01 | 2019-09-19 | |
| Develop and Implement Methods for Diagnostic and Treatment of Hormonal Disorders in Patients With Chronic Kidney Disease Ultrasound, DXA, hormonal tests - Hyperprolactinemia, Thyroid Dysfunction | Unknown | Belarusian State Medical University | 400 | 2018-01-01 | 2020-06-23 | |
| Administration of Kisspeptin in Patients With Hyperprolactinemia Kisspeptin 112-121, GnRH - Hyperprolactinemia, Hypogonadism | Phase 2 | Completed | Massachusetts General Hospital | 36 | 2017-11-17 | 2024-10-01 |
| Hyperprolactinaemia Management in Reproductive Services at University Hospital of Coventry and Warwickshire MRI Pituitary - Hyperprolactinemia, Subfertility | Completed | University Hospitals Coventry and Warwickshire NHS Trust | 107 | 2017-09-25 | 2018-06-26 | |
| Treatment of Hyperprolactinemia With the Non-ergoline Dopamine Agonist Ropinirole Ropinirole - Hyperprolactinemia, Prolactinoma | Phase 1 / Phase 2 | Completed | Columbia University | 16 | 2016-09-16 | 2024-06-04 |
| Pituitary Function and Spontaneous Intracranial Hypotension Pituitary panel will be drawn pre-op and post-op for all patients. - Hyperprolactinemia, Spontaneous Intracranial Hypotension | Suspended | Cedars-Sinai Medical Center | 100 | 2015-07-01 | 2019-01-31 | |
| Pituitary Histopathology and Hyperprolactinaemia and Risk of Glucose Metabolic Disturbances in Acromegaly. Acromegaly, Surgery | Unknown | Copenhagen University Hospital, Rigshospitalet | 79 | 2013-09-01 | 2017-05-03 | |
| Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEON Fertility treatment - Polycystic Ovary Syndrome, Endometriosis | Completed | University of Zurich | 123 | 2013-09-01 | 2016-09-07 |
Showing 20 of 39. Sign in to see all of them.
Schizophrenia (10) · Polycystic Ovary Syndrome (4) · Prolactinoma (4) · Hypogonadism (3) · Infertility (3) · Endometriosis (2) · Insulin Resistance (2) · Parkinson Disease (2) · Acromegaly (1) · Bone Diseases, Metabolic (1) · Dyslipidemias (1) · Growth Disorders (1) · Health Education (1) · Heart Valve Diseases (1)
Brain Diseases (39) · Central Nervous System Diseases (39) · Endocrine System Diseases (39) · Hyperpituitarism (39) · Hypothalamic Diseases (39) · Nervous System Diseases (39) · Pituitary Diseases (39) · Mental Disorders (10) · Schizophrenia Spectrum and Other Psychotic Disorders (9) · Urogenital Diseases (9) · Genital Diseases (8) · Neoplasms (8) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Gonadal Disorders (6)
Cabergoline (6) · Aripiprazole (5) · Bromocriptine (2) · Gonadotropin-Releasing Hormone (2) · Absorptiometry, Photon (1) · Amantadine (1) · Antipsychotic Agents (1) · Calcium (1) · Clomiphene (1) · Dopamine Agonists (1) · Drug Evaluation (1) · Hematologic Tests (1) · High-Energy Shock Waves (1) · Luteinizing Hormone, beta Subunit (1) · Metformin (1)
Changchun GeneScience Pharmaceutical Co., Ltd. (2) · Massachusetts General Hospital (2) · Pfizer (2) · Shanghai Mental Health Center (2) · Assiut University (1) · Beijing HuiLongGuan Hospital (1) · Belarusian State Medical University (1) · Cedars-Sinai Medical Center (1) · Chadi A. Calarge (1) · Columbia University (1) · Copenhagen University Hospital, Rigshospitalet (1) · David C. Henderson, MD (1) · Fayoum University (1) · Genovate Biotechnology Co., Ltd., (1) · Insel Gruppe AG, University Hospital Bern (1)
United States (8) · China (7) · Denmark (3) · Switzerland (3) · Brazil (2) · Egypt (2) · Taiwan (2) · United Kingdom (2) · Belarus (1) · France (1) · Germany (1) · Japan (1) · Spain (1)
Atef M Darwish, Prof (1) · Brigitte Leeners, MD (1) · Chadi Calarge, M.D. (1) · Chen Chih-Ken, PhD (1) · Cihan Atila, Dr. (1) · David C. Henderson, M.D. (1) · David Launay, MD,PhD (1) · Deanna L Kelly, Pharm.D., BCPP (1) · Erika CO Naliato, MSc (1) · Gabrielle Page-Wilson, M.D. (1) · Guy M Goodwin, PhD (1) · Huafang Li, MD, PhD (1) · Kun Ma, Dr. (1)
PMID 1430082, PMID 15687336, PMID 16899562, PMID 20732372, PMID 21055747, PMID 25226293, PMID 27755159, PMID 29112461, PMID 31132118, PMID 31244718, PMID 35804385, PMID 37715962, PMID 39965102, PMID 40830714, PMID 41273106, PMID 9284753
2009 (1), 2025 (1), K23MH085005 (1), R21DK112093 (1)